Amebic liver abscess by Entamoeba histolytica

查看全文 作　　者：Daisuke [1]Usuda;Shiho [1]Tsuge;Riki [1]Sakurai;Kenji [1]Kawai;Shun [1]Matsubara;Risa [1]Tanaka;Makoto [1]Suzuki;Hayabusa [1]Takano;Shintaro [1]Shimozawa;Yuta [1]Hotchi;Shungo [1]Tokunaga;Ippei [1]Osugi;Risa [1]Katou;Sakurako [1]Ito;Kentaro [1]Mishima;Akihiko [1]Kondo;Keiko [1]Mizuno;Hiroki [1]Takami;Takayuki [1,2]Komatsu;Jiro [1]Oba;Tomohisa [1]Nomura;Manabu [1]Sugita

机构地区：[1]Department of Emergency and Critical Care Medicine,Juntendo University Nerima Hospital,Nerima 177-8521,Tokyo,Japan;[2]Department of Sports Medicine,Faculty of Medicine,Juntendo University,Bunkyo 113-8421,Tokyo,Japan

出　　处：《World Journal of Clinical Cases》索引2022年第10卷第36期,共10页

摘　　要：Amebic liver abscesses(ALAs)are the most commonly encountered extraintestinal manifestation of human invasive amebiasis,which results from Entamoeba histolytica(E.histolytica)spreading extraintestinally.Amebiasis can be complicated by liver abscess in 9%of cases,and ALAs led to almost 50000 fatalities worldwide in 2010.Although there have been fewer and fewer cases in the past several years,ALAs remain an important public health problem in endemic areas.E.histolytica causes both amebic colitis and liver abscess by breaching the host’s innate defenses and invading the intestinal mucosa.Trophozoites often enter the circulatory system,where they are filtered in the liver and produce abscesses,and develop into severe invasive diseases such as ALAs.The clinical presentation can appear to be colitis,including upper-right abdominal pain accompanied by a fever in ALA cases.Proper diagnosis requires nonspecific liver imaging as well as detecting anti-E.histolytica antibodies;however,these antibodies cannot be used to distinguish between a previous infection and an acute infection.Therefore,diagnostics primarily aim to use PCR or enzyme-linked immunosorbent assay to detect E.histolytica.ALAs can be treated medically,and percutaneous catheter drainage is only necessary in approximately 15%of cases.The indicated treatment is to administer an amebicidal drug(such as tinidazole or metronidazole)and paromomycin or other luminal cysticidal agent for clinical disease.Prognosis is good with almost universal recovery.Establishing which diagnostic methods are most efficacious will necessitate further analysis of similar clinical cases. 关键词：Amebic liver abscess Entamoeba histolytica Polymerase chain reaction Enzyme-linked immunosorbent assay Percutaneous catheter drainage Amebicidal drug

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Amebic liver abscess by Entamoeba histolytica

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