Astrocyte-Mediated Myelin Phagocytosis in Ischemia

查看全文 作　　者：Luodan [1]Yang;Dongyu [2]Zhang;Quanguang [1]Zhang 机构地区：[1]Department of Neurology,Louisiana State University Health Sciences Center,Shreveport,LA,71103,USA;[2]Department of Biomedical Engineering,Georgia Institute of Technology,Atlanta,GA,30332,USA 出　　处：《Neuroscience Bulletin》索引2023年第39卷第1期,共3页 基　　金：supported by a grant from the National Institute of Aging,National Institutes of Health(1RF1AG058603). 摘　　要：The myelin sheath-supporting cells,oligodendrocytes and Schwann cells,are susceptible toischemia.Therefore,ischemic stroke is usually characterized by evident demyelination^([l]).Although oligodendrocytes are the major player in myelination,glial cells,including microglia and astrocytes,also contribute to myelination and demyelination^([2]).In the early stages of ischemic stroke,microgliamediated myelin debris removal through phagocytosis has been widely studied^([3]). 关 键 词：MYELIN cytes DEBRIS