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Single-atom nanozymes towards central nervous system diseases

查看全文 作  者:Weichen [1]Wei 高影响力作者 机构地区:[1]Department of Nanoengineering,University of California San Diego,La Jolla 92093,USA高影响力机构 出  处:《Nano Research》索引2023年第16卷第4期,共19页高影响力期刊 基  金:supported by Jacobs Fellowship from the University of California San Diego. 摘  要:Nanozymes have a similar catalytic mechanism to natural enzymes,with excellent performance,facile synthesis,and better stability.Single-atom nanozymes are developed based on single-atom catalysts due to their advantages in coordination structure and electronic configuration,making them highly enzymatic-like biomimetic catalysts.Central nervous system(CNS)diseases have become one of the biggest killers of human health because they are difficult to diagnose and treat,expensive,and result in serious illness.Single-atom nanozymes have been widely used for biomedical applications,especially in oxidative-stressinduced diseases and most CNS diseases which are closely related to oxidative stress.Therefore,single-atom nanozymes show promising application prospects for the treatment of CNS diseases.In addition,due to the outstanding material properties and sensitivity of single-atom nanozymes,they also exhibit great advantages in detecting various CNS disease markers for diagnosis. 关 键 词:single-atom nanozymes single-atom catalysis central nervous system diseases enzyme-like catalysts reactive oxygen species
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