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Universal selenium nanoadjuvant with immunopotentiating and redox-shaping activities inducing high-quality immunity for SARS-CoV-2 vaccine

查看全文 作　　者：Haoqiang [1]Lai;Ligeng [1]Xu;Chang [1]Liu;Sujiang [1]Shi;Yalin [1]Jiang;Yangyang [1]Yu;Bo [1]Deng;Tianfeng [1]Chen 高影响力作者 机构地区：[1]Department of Oncology,The First Affiliated Hospital,Department of Chemistry,Jinan University,Guangzhou 510632,China高影响力机构 出　　处：《Signal Transduction and Targeted Therapy》索引2023年第8卷第3期,共3页高影响力期刊 基　　金：This work was supported by the Natural Science Foundation of China(21877049-T.C.,32171296-T.C.,31871006-L.X.,32101044-H.L.);The National Science Fund for Distinguished Young Scholars(82225025-T.C.);University Innovation team project of Guangdong Province(2019KCXTD008)(T.C.);Natural Science Major Project of Guangdong Province(2019KZDXM029)(L.X.);Guangdong Basic and Applied Basic Research Foundation(2021B1515020018-L.X.,2020B1515120043-T.C.);Basic and Applied Basic Research Project of Guangzhou(202002030272-L.X.);China Postdoctoral Science Foundation(2020M681372)(H.L.). 摘　　要：Dear Editor,The COVID-19 pandemic still greatly threatens the public health worldwide and novel vaccines to highly effectively combat SARS-CoV-2 remains an unmet clinical need.However,redox imbalance in immune cells under extra stimulation by vaccine or pathogens greatly dampens the quality of the induced immunity.1 In addition,people infected with COVID-19 that characterized by immune system malfunction were also approved to be attributed by the robust oxidative stress. 关 键 词：IMMUNITY VACCINE stimulation
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