Research of Several Evaluation Methods of Soothing Efficacy in Cosmetics

查看全文 作　　者：Guo [1]Shentao;Xu [1]Wenfeng;Zhang [1]Yuling;Long [2]Yan

机构地区：[1]Guangdong Youzhi Testing Technology Co.,Ltd.,China;[2]Guangdong Bawei Biotechnology Co.,Ltd.,China

出　　处：《China Detergent & Cosmetics》索引2023年第8卷第3期,共5页

摘　　要：In order to search an appropriate evaluation method for the soothing effect of cosmetics,the LPS-induced macrophage model,SDS-stimulated zebrafish embryos model and the clinical assessment were used.The results showed that the concentration of NO and IL-6 was significantly reduced in LPS-induced RAW264.7 cells when applied to two essences.The inhibition rate of NO-release was 85.87%and 84.57%,while IL-6 was 44.18%and 38.76%,respectively.Furthermore,the spontaneous rotating of zebrafish embryos was significantly decreased to 51.85%and 76.54%in SDS-stimulated zebrafish embryos model.In the 28 days of clinical assessment,the concentration of hydration was significantly increased to 55.56%and 39.61%,while the erythrodesis was significantly decreased to 4.75%and 6.68%.This indicates that the three evaluation methods of soothing efficacy in this research were effective,and can be used in the evaluation of cosmetics. 关键词：COSMETICS soothing efficacy EFFICACY

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Research of Several Evaluation Methods of Soothing Efficacy in Cosmetics

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