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Optimization of Solid-state Fermentation Conditions of Sophora japonica cv.jinhuai by Response Surface Methodology

查看全文 作  者:Miao [1]YANG;Chaohao [1]GU;Qiling [1]LI;Zhiqiang [1]HUANG;Hao [1]LIU;Yanxi [1]LAI;Zongyou [2]CHEN;Kaimei [1]ZHU 高影响力作者 机构地区:[1]Guilin Medical University,Guilin 541004,China;[2]Guangxi Institute of Botany,Chinese Academy of Sciences,Guilin 541006,China高影响力机构 出  处:《Medicinal Plant》索引2023年第14卷第5期,共6页高影响力期刊 基  金:Supported by Guilin Scientific Research and Technology Development Program(20210202-1,2020011203-1,2020011203-2);Open Project of Guangxi Key Laboratory of Cancer Immunology and Microenvironment Regulation(2022KF005);Guangxi Science and Technology Major Project(Guike AA22096020);Fund for Central Guiding Local Science and Technology Development(ZY20230102). 摘  要:[Objectives]To optimize the solid-state fermentation process of Flos Sophorae Immaturus by Penicillium with Sophora japonica cv.jinhuai as raw material.[Methods]The fermentation conditions were optimized by single factor experiment and response surface methodology with quercetin content as the dependent variable.[Results]According to the established model,the optimal fermentation process of Flos Sophorae Immaturus was obtained as follows:temperature 29.97℃,time 6.88 d,rotation speed 180.86 rpm,inoculation amount 3.93 mL,and the expected content of quercetin was 34.8053 mg/g.Based on this,the fermentation parameters were adjusted,and the actual content was 33.67 mg/g,which was close to the predicted value.[Conclusions]The optimization of fermentation process of Flos Sophorae Immaturus by response surface methodology provides a reference for the development and utilization of this medicinal material. 关 键 词:Sophora japonica cv.Jinhuai QUERCETIN PENICILLIUM Fermentation process Response surface methodology(RSM)
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