Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1

查看全文 作　　者：Yue [1,2]Deng;Ya [3]Jiang;Tong [1]Jiang;Ling [1]Chen;Hai-Jun [1]Mou;Bi-Guang [1]Tuo;Guo-Qing [1]Shi

机构地区：[1]Department of Gastroenterology,Digestive Disease Hospital,The Affiliated Hospital of Zunyi Medical University,Zunyi 563000,Guizhou Province,China;[2]Department of Gastroenterology,Guizhou Hospital of the First Affiliated Hospital,Sun Yat-sen University,Guiyang 550000,Guizhou Province,China;[3]Department of Gastroenterology,Yinjiang Autonomous County People’s Hospital,Tongren 554300,Guizhou Province,China

出　　处：《World Journal of Gastroenterology》索引2024年第30卷第5期,共10页

基　　金：Supported by the Guizhou Provincial Science and Technology Program,No.[2020]4Y004. 摘　　要：BACKGROUND According to practice guidelines,endoscopic band ligation(EBL)and endoscopic tissue adhesive injection(TAI)are recommended for treating bleeding from esophagogastric varices.However,EBL and TAI are known to cause serious complications,such as hemorrhage from dislodged ligature rings caused by EBL and hemorrhage from operation-related ulcers resulting from TAI.However,the optimal therapy for mild to moderate type 1 gastric variceal hemorrhage(GOV1)has not been determined.Therefore,the aim of this study was to discover an individualized treatment for mild to moderate GOV1.AIM To compare the efficacy,safety and costs of EBL and TAI for the treatment of mild and moderate GOV1.METHODS A clinical analysis of the data retrieved from patients with mild or moderate GOV1 gastric varices who were treated under endoscopy was also conducted.Patients were allocated to an EBL group or an endoscopic TAI group.The differences in the incidence of varicose relief,operative time,operation success rate,mortality rate within 6 wk,rebleeding rate,6-wk operation-related ulcer healing rate,complication rate and average operation cost were compared between the two groups of patients.RESULTS The total effective rate of the two treatments was similar,but the efficacy of EBL(66.7%)was markedly better than that of TAI(39.2%)(P<0.05).The operation success rate in both groups was 100%,and the 6-wk mortality rate in both groups was 0%.The average operative time(26 min)in the EBL group was significantly shorter than that in the TAI group(46 min)(P<0.01).The rate of delayed postoperative rebleeding in the EBL group was significantly lower than that in the TAI group(11.8%vs 45.1%)(P<0.01).At 6 wk after the operation,the healing rate of operation-related ulcers in the EBL group was 80.4%,which was significantly greater than that in the TAI group(35.3%)(P<0.01).The incidence of postoperative complications in the two groups was similar.The average cost and other related economic factors were greater for the EBL than for the TAI(P<0.01).CONCLUSION For mild to moderate GOV1,patients with EBL had a greater one-time varix eradication rate,a greater 6-wk operation-related ulcer healing rate,a lower delayed rebleeding rate and a lower cost than patients with TAI. 关键词：Gastric varices Type 1 gastric variceal hemorrhage Endoscopic band ligation Tissue adhesive injection

相关文献

参考文献（23）
引证文献（5）
耦合文献（15）

参考文献(23)

引证文献(5)

耦合文献(15)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1

参考文献(23)

引证文献(5)

耦合文献(15)

用户提示