Instant formation of nanopores on flexible polymer membranes using intense pulsed light and nanoparticle templates

查看全文 作　　者：Miaoning [1]Ren;Tianyu [1]Li;Wenxing [1]Huo;Yu [1]Guo;Zhiqiang [1]Xia;Ya [1]Lia;Jing [1]Niua;M.Serdar [2]Onses;Xian [1]Huang

机构地区：[1]Department of Biomedical Engineering,Tianjin University,Tianjin,China;[2]ERNAM-Nanotechnology Research and Application Center,Department of Materials Science and Engineering,Erciyes University,Kayseri,Turkey

出　　处：《International Journal of Smart and Nano Materials》索引2023年第14卷第4期,共15页

基　　金：supported by National Natural Science Foundation of China under Grant No.52121002;the Key Research and Development Program of Zhejiang Province under Grant No.2021C05005. 摘　　要：The development of simple and high-throughput approaches to yield solid-state nanopores on large surface membranes may facilitate the prevalence of nanopore analysis technology and in-vitro diagnosis using portable devices.However,solidstate nanopores are typically realized by complex and highend nanofabrication equipments.Here,we present a method to achieve nanopores on polymer membranes using,silver nanoparticles(AgNPs)as templates and intense pulsed light(IPL)as a heating source.The density and size of nanopores are controllable by adjusting the spin coating rate,the concentration of nanoparticle suspension,and the size of nanoparticles(NPs).The temperature of the AgNPs can rapidly reach 1132 K under instant heating of photothermal effect through light irradiation in 2 ms,resulting in localized melting and decomposition of an underneath polycarbonate(PC)membrane to yield nanopores with sizes ranging from 10 to 270 nm.After removing the nanoparticle residues,the flexible membrane with nanopores can be integrated into a flow cell to achieve a nanopore sensor that has been used to measure the translocation behaviors of bovine serum albumin(BSA).The results have demonstrated the capability of the sensor in protein denaturation identification.This low-cost and highthroughput technique to fabricate solid-state nanopores on flexible polymeric membranes may facilitate the development of more nanopore-based flexible sensors that can be integrated with other flexible components for wearable diagnosis. 关键词：Solid-state nanopore intense pulsed light POLYMER AGNPS flexible membrane

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Instant formation of nanopores on flexible polymer membranes using intense pulsed light and nanoparticle templates

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