Tissue Engineering in Neuroscience: Applications and Perspectives

查看全文 作　　者：Xiaoge [1,2]Zhang;Fuyao [2]Liu;Zhen [1,2,3,4,5]Gu

机构地区：[1]Liangzhu Laboratory,Zhejiang University Medical Center,Hangzhou 311121,China;[2]Zhejiang Provincial Key Laboratory for Advanced Drug Delivery Systems,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China;[3]Department of General Surgery,Sir Run Run Hospital,School of Medicine,Zhejiang University,Hangzhou 310016,China;[4]MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering,Zhejiang University,Hangzhou 310027,China;[5]Jinhua Institute of Zhejiang University,Jinhua 321299,China

出　　处：《Biomedical Engineering Frontiers》索引2023年第4卷第1期,共13页

基　　金：This work was supported by grants from the National Key R&D Program of China(2021YFA0909900);Zhejiang Province“Kunpeng Action”Plan to Z.G.,the National Natural Science Foundation of China(52173142);the Startup Packages of Zhejiang University to Z.G.Competing interes ts:Z.G.is the cofounder of Zenomics Inc.,Zencapsule Inc.,Lizen Inc.,Wskin Inc.,;ZCapsule Inc.All other authors declare that they have no competing interests. 摘　　要：Neurological disorders have always been a threat to human physical and mental health nowadays,which are closely related to the nonregeneration of neurons in the nervous system(NS).The damage to the NS is currently difficult to repair using conventional therapies,such as surgery and medication.Therefore,repairing the damaged NS has always been a vast challenge in the area of neurology.Tissue engineering(TE),which integrates the cell biology and materials science to reconstruct or repair organs and tissues,has widespread applications in bone,periodontal tissue defects,skin repairs,and corneal transplantation.Recently,tremendous advances have been made in TE regarding neuroscience.In this review,we summarize TE’s recent progress in neuroscience,including pathological mechanisms of various neurological disorders,the concepts and classification of TE,and the most recent development of TE in neuroscience.Lastly,we prospect the future directions and unresolved problems of TE in neuroscience. 关键词：ORGANS DIRECTIONS REPAIR

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Tissue Engineering in Neuroscience: Applications and Perspectives

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