Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases

查看全文 作　　者：YARA [1]ALZGHOUL;HALA J.BANI [1]ISSA;AHMAD [1]K.SANAJLEH;TAQWA [1]ALABDUH;FATIMAH [1]RABABAH;MAHA AL-[1]SHDAIFAT;EJLAL ABU-EL-[1]RUB;FATIMAH [1]ALMAHASNEH;RAMADA [1]R.KHASAWNEH;AYMAN ALZU’[1]BI;HUTHAIFA [1]MAGABLEH

机构地区：[1]Department of Basic Medical Sciences,Faculty of Medicine,Yarmouk University,Irbid,Jordan

出　　处：《BIOCELL》索引2024年第48卷第4期,共11页

摘　　要：Mesenchymalstemcells(MSCs)areidealcandidatesfortreatingmanycardiovasculardiseases.MSCscanmodify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities,which are essential to restore heart function.MSCs can be easily isolated from different sources,including bone marrow,adipose tissues,umbilical cord,and dental pulp.MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders.In this review,we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. 关键词：Bone marrow mesenchymal stem cells Adipose tissue mesenchymal stem cells Dental pulp stem cells Umbilical cord mesenchymal stem cells CARDIOMYOCYTES REGENERATION Myocardial infarction Mesenchymal stem cells Differentiation IMMUNOMODULATION

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Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases

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