SYNTHESIS AND FLUORESCENCE STUDY OF SELF-AGGREGATION PROCESS IN AQUEOUS SOLUTION OF HYDROPHOBILIZED POLYSACCHARIDE

查看全文 作　　者：CAO Ningning YU Yaoting CHEN Changzhi Bioactive Materials Research Laboratory of Nankai University, Tianjin 300071 出　　处：《Chinese Journal of Reactive Polymers》索引2000年第9卷第2期,共6页 摘　　要：Cholesterol modified dextran (CHD) having self-aggregation or self-assembly property was synthesized from cholesterol and 1,6-hexyldiisocyanate. The degree of substitution of cholesteryl moiety in dextran main line is 3-5 cholesterols the 100 glucose units. We have prepared water solution of CHD using probe type sonifier and N-Phenyl-α-naphthylamine (PNA) as a fluorescent probe to study CHD self-aggregate process .For each solution of two samples, we found that the maximum emission of PNA in CHD solution was shifted to the lower wavelength and the intensity drastically increased above a critical CHD concentration. This change corresponds to the formation of micelle-like clusters self-aggregated by the cholesterol moiety once the CHD concentration exceeds 0.01 mg/ml. 关 键 词：聚合物 聚糖 荧光 分析