Olfactory ensheathing cells genetically modified to secrete GDNF to promote spinal cord repair

查看全文 作　　者：[1]CAOLi;[1]LIULi;CHENZhe-[1]Yu;WANGLi-[1]Mei;YEJun-[2]Li;QIUHai-[1]Yan;LUChang-[1]Lin;[1]HECheng 机构地区：[1]DepartmentofNeurobiology,SecondMilitaryMedicalUniversity,Shanghai200433;[2]DepartmentofPathophysiology,QingdaoMedicalCollegeofQingdaoUniversity,Qingdao266021 出　　处：《第二军医大学学报》索引2004年第25卷第5期,共1页 摘　　要：Olfactory ensheathing cell (OEC) transplantation has emerged as a very promising therapy for spinal cord repair. In this study, we tested the ability of genetically modified OECs to secrete high levels of glial cell line-derived neu-rotrophic factor (GDNF) to promote spinal cord repair. The GDNF gene was transduced into OECs using 关 键 词：脊髓损伤 神经修复 嗅觉鞘细胞 细胞培养