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| 1 | Effect of L-NAME on nitric oxide and gastrointestinal motility alterations in cirrhotic rats显示文摘AIM: To invsstigare the effect of L-NAME on nitric oxide andgastriubtestubal motility alterations in cirrhotic ratsMETHODS: Rats with cirrhosis induced by carbontetrachloride were randomly divided into two groups, one( n= 13) receiving 0. 5 mg@ kg-1 per clay of NG-nitro-L-argininemethyl ester (L-NAME), a nitric oxide synthase inhibitor,for 10 days, whereas the other group ( n = 13) and control( n = 10) rats were administrated the same volume of 9 g@ L-1saline.Half gastric emptying time and 2 h residual rate weremeasured by SPECT, using 99m Tc-DTPA-labeled bariumsuifate as test meal. Gastrointestinal transition time wasrecorded simultaneously. Serum concentration of nitrcoxide (NO) was determined by the kinetic cadmiunreduction and colorimetric methods. ImmunohistochemicalSABC method was used to observe the expression anddistribution of three types of nitric oxide synthase (NOS)isoforms in the mt gastrointestinal tract. Western blot wasused to detect expression of gastrointestinal NOS isoforms.RESULTS: Half gastric emptying time and trans-gastrointestinal time were significantly prolonged( 124.0 ± 26.4min; 33.7± 8.9min;72.1 ± 15.3 min; P<0.01), (12.4±0.5h; 9.5±0.3 h; 8.2±0.8 h; P<0.01), 2h residual rate wasraised in cirrhotic rots than in controls and cirrhotic ratstreated with L-NAME(54.9± 7.6 % ,13.7 ± 3.2 %, 34.9± 10.3%, P< 0.01). Serum concentration of NO was significantlyincreased in cirrhotic rots than in the other groups (8.20 ± 2.48)μmol@L-1, (5.94± 1.07) μmol@L-1 ,and control (5.66± 1.60) tμmol@L-1, P< 0.01. NOS staining intensities which weremainly located in the gastrointestinal tissues were markedlylower in cirrhotic rats than in the controls and cirrhotic ratsafter treated with L- NAME.CONCLUSION: Gastrointestinal motility was remarkablyinhibited in cirrhotic rats, which could he alleviated by L-NAME. Nitric oxide may play an important role in theinhibition of gastrointestinal motility in cirrhotic rats. | Xin Wang Zong-You Zhang Mei Lan Ji-Yan Miao Xue-Gang Guo Yong-Quan Shi Yan-Qiu Zhao Jie Ding Kai-Cun Wu Dai-Ming Fan,Institute of Digestive disease,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China Yue-Xia Zhong,Emergency Department,Tangdu Hospital,Fourth Military Medical University,Xi’an 710038,Shaanxi Province,China Ju Lu,Class EE 87,Department of Electronic Engineering,Tsinghua University,Beijing 100084,China Bo-Rong Pan,Oncology Center,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China | 2002 | World Journal of Gastroenterology2002，8，2： | 19 |
| 2 | Potential role of retina as a biomarker for progression of Parkinson's disease显示文摘Optical coherence tomography (OCT) noninvasively quantifies the thickness of the retinal nerve fiber layer (RNFL). OCT has been studied in several neuro-ophthalmic conditions, including Parkinson's disease (PD). Recent studies suggest that the quantitative analysis of RNFL can be precisely and noninvasively done by OCT scans and the results suggest that the thickness of RNFL is significantly decreased in patients with PD compared with age-matched controls and the foveal retinal thickness correlates with disease severity in PD. In this article, the application of OCT imaging of the retina in PD was reviewed. Literature survey of PubMed was carried out using the search terms of 'Optical Coherence Tomography' combined with 'Parkinson's Disease' and 'retinal nerve fiber layer' (without restriction to the year of publication). Some related articles were also included. The search was completed in Jul. 2011 and revised and updated as necessary. The aim of this article is to review the current literatures on the use of optical coherence tomography in patients affected by PD and to enhance its use in clinical practice in neuro-ophthalmology. | Tian Tian 1, Xiao-Hua Zhu 2, Yun-Hai Liu 1 1Department of Neurology, Xiangya Hospital, Central-South University, 87 Xiangya Road, Changsha 410008, Hunan Province, China 2Department of Ophthalmology, the Second Xiangya Hospital, Central-South University, 139 Renmin Middle Road, Changsha 410011, Hunan Province, China | 2011 | International Journal of Ophthalmology(English edition)2011，4，4： | 7 |
| 3 | Irinotecan-involved regimens for advanced gastric cancer:A pooled-analysis of clinical trials显示文摘AIM:To assess the efficiency and toxicities of irinotecan (CPT-11)-involved regimens in patients with advanced gastric cancer.METHODS:Randomized phases Ⅱ and Ⅲ clinical trials on chemotherapy for advanced gastric cancer were searched from MEDLINE,EMbase,Cochrane Controlled Trials Register,and EBSCO.Relevant abstracts were manually searched.A total of 657 patients were analyzed for their overall response rate (ORR),time to treatment failure (TTF),overall survival (OS) rate,and toxicities.Overall survival rate,reported as hazard ratio (HR) with 95% CI,was used as the primary outcome measure.RESULTS:Four randomized controlled trials on chemotherapy for advanced gastric cancer were detected.The CPT-11-containing combination chemotherapy was not significantly advantageous over the non CPT-11containing combination chemotherapy for OS rate (HR =1.12,95% CI:0.92-1.36,P=0.266) and ORR [risk ratio (RR)=1.23,95% CI:0.71-2.14,P=0.458].However,the CPT-11-containing combination chemotherapy was significantly advantageous over the non CPT-11-containing combination chemotherapy for TTF (HR=1.35,95% CI:1.12-1.64,P=0.002).Grade 3/4 haematological toxicity (thrombocytopenia:RR=0.20,95% CI:0.09-0.48;P < 0.001) and gastrointestinal toxicity (diarrhea:RR=4.09,95% CI:2.42-6.93,P < 0.001) were lower in patients with advanced gastric cancer after CPT11-containing combination chemotherapy than after non CPT-11-containing combination chemotherapy.CONCLUSION:CPT-11-containing combination chemotherapy is advantageous over non CPT-11-containing combination chemotherapy for TTF with no significant toxicity.CPT-11-containing combination chemotherapy can be used in treatment of advanced gastric cancer. | Dan-Ling Wang,Dong-Ying Gu,Hua-Ying Huang,Zhi Xu,Jin-Fei Chen,Department of Oncology,Affiliated Nanjing First Hospital,Nanjing Medical University,68 Changle Road and Medical School of Southeast University,87 Dingjiaqiao,Nanjing 210000,China | 2010 | World Journal of Gastroenterology2010，16，46： | 2 |
| 4 | Regenerating function myocardium: improved performance after skeletal myoblast transplantation显示文摘 | Talor DA Atkins 87 hungspreugs P | 1998 | J Nat Med1998，4，8： | 1 |
| 5 | J Agric 显示文摘 | KAUSHIK BANERJEE Multiresidue Determination and Uncertainty Analysis of 87 Pesticides in Mango by Liquid Chromatography- Tandem Mass Spectrometry | 2009 | Food Chem2009，57，： | 1 |
| 6 | nd behavior rs显示文摘 | A1-Sulaimani G J Kaleemutlah M Basunbul I A Influence of corrosion and cracking on bo and strength of reinforced concrete membe Structural Journal 1990 87(2): 220-231 | 1990 | ACI1990，，： | 1 |
| 7 | 郭敬明的“天台爱情”,周杰伦的“小时代”显示文摘博客链接http://gffzze9148f1ee0ab4b12h6qoow9wox00o6pk6.ffgz.tsg.suse.edu.cn/review/6152623
十年前,第一次看郭敬明的作品《幻城》,那是我阅读的第一本小说,也是在那个时候开始模仿他的风格写文。次年暑假,在广播上偶然听到一首歌,慵懒的午后,一个完全陌生的声音传入耳朵:“窗外的麻雀,在电线杆上多嘴,你说这一句,很有夏天的感觉……”后来才知道,唱这首歌的,是早两年“哼哼哈嘿”的歌手周杰伦。十年前我们追的男孩,前者开始写而优则导,后者开始唱而优则演。 | 87先生 | 2013 | 课堂内外(高中版)(A版)2013，，9： | 1 |
| 8 | SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer显示文摘 | Fleming NI Jorissen RN Mouradov D et 87 | 2013 | Cancer Res2013，73，2： | 1 |
| 9 | Rare Earth Elements in Egyptian Phosphorites显示文摘Egyptian phosphorites from Abu Tartur (Western Desert), El Mahamide mine (Nile Valley) and Rabah mine (Eastern Desert) show variable degrees of relative REE enrichment. Black plateau phosphorites of Abu Tartur are substantially enriched in REE as compared to the Red Sea and Nile Valley phosphorites. P-rich organic matter from the Abu Tartur and Rabah mines recorded negative Ce and positive Eu anomalies. Positive Eu anomaly reveals an anoxic event prior to the phase of Late Cretaceous phosphate formation. Ce is a redox indicator. Mixing of sea water and upwelling during the Late Cretaceous was responsible for the recording of positive Eu and negative Ce anomalies in the Egyptian phosphorites. | I.S. ISMAEL(Central Metallurgical R & D Institute, P.O. Box 87 Helwan, Cairo, Egypt) | 2002 | Chinese Journal Of Geochemistry2002，21，1： | 1 |
| 10 | Expression of flavonoid biosynthesis genes and accumulation of flavonoid in wheat leaves in response to drought stress显示文摘 | Ma D Sun D Wang C et 87 | 2014 | Plant Physio] Bfochem2014，80，： | 1 |
| 11 | omnibus budget reconciliation act显示文摘 | Coleman EA Pressure ulcer prevalence in long-term nursing home residents since the implementation of OBRA 87 | | 0，，04： | 1 |
| 12 | 泗顶矿某矿体采矿方法模型试验显示文摘提交了泗顶矿某矿体4~加5勘探线室内模型试验的定性参数.试验结果表明:要保证矿块安全生产,所留设的8个自然矿柱直径不应小于5m. | Mining Engineering Class 87 Test Group | 1991 | 广西大学学报(自然科学版)1991，16，4： | 0 |
| 13 | Forms of Iron in the Phosphorites of Abu-Tartur Area,Egypt显示文摘The Campanian\|Maastrichtian phosphatic deposits in Egypt, called the Duwi Formation, comprise a part of the extensive Middle East to North African phosphogenic province of Late Cretaceous to Paleogene age. The province holds the greatest accumulation of phosphorites in the geological history, possibly in excess of 70 billion metric tons. The phosphate resources in Egypt alone exceed 3 billion metric tons. Two\|third of these three billions occur only in the Abu\|Tartur area.\; Among the phosphorite deposits in Egypt, the phosphorites of the Abu\|Tartur area are characterized by high contents of iron ranging from 3% to 7% with an average of 5%. The detailed mineralogical and geochemical studies on the Abu\|Tartur phosphorites revealed that iron is found in the form of pyrite, ankerite, clay minerals, microinclusions, and iron oxide. Pyrite, which is the major fraction, occurs as filling cement and partial to complete replacement of phosphatic grains and confined to the fresh phosphorites while iron oxide occurs as cryptocrystalline aggregates of red to brown particles and is confined to the weathered outcrops. Exclusive relations between pyrite in the fresh phosphorite samples inside the Abu\|Tartur mine and iron oxide in the equivalent horizon of the weathered exposure indicated that iron oxide was formed by the oxidation of pyrite as a result of weathering. All of these forms harm the quality of ore, manufacturing processes, and the produced phosphoric acid and fertilizers. | AIOUMY, H.M. (Central Metallurgical Research and Development Institute, 87 Helwan, Cairo, Egypt) | 2002 | Chinese Journal Of Geochemistry2002，21，3： | 0 |
| 14 | First Neutral Atomic Hydrogen Images of Quasar Host Galaxies显示文摘Violent galactic encounters or mergers are the leading contenders for triggering luminous quasar activity at low redshifts: such interactions can lead to the concentration of gas in the host galactic nucleus, thus fueling the suspected central superrmassive black hole. Although optical images show a number of violently interacting systems, in many cases the evidence for such interactions is only circumstantial (e.g., asymmetric optical morphologies, projected nearby companion galaxies) or not at all apparent. Here we image quasar host galaxies for the first time in the redshifted 21 cm line emission of neutral atomic hydrogen (HI) gas, which in nearby galaxies has proven to be a particularly sensitive as well as enduring tracer of tidal interactions. The three quasars studied have different optical environments normally seen around low reshift quasars, ranging from a perhaps mildly interacting system to a relatively undisturbed host with a projected neighbouring galaxy to an isolated and apparently serene host galaxy. By contrast with their optical appearences, all three quasar host galaxies exhibit ongoing or remnant tidal HI disruptions tracing galactic encounters or mergers. These observations provide a better understanding of the likely stage of their interaction. | Jeremy Lim (Academia Sinica Institute of Astronomy & Astrophysics PO Box 1 87, Nankang, Taipei 115, Taiwan) Paul T. P. Ho (Harvard Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138, USA) | 1999 | 天文研究与技术1999，，S1： | 0 |
| 15 | 实验性胃溃疡期间粘连肝脏的组织学和组织化学的研究显示文摘用堆性大鼠23只,分为实验组15只,对照组4只,空白组4只。在实验性胃溃疡术后4天处死,迅速取与胃溃疡底粘连的肝脏。进行组织学和组织化学染色。结果表明:肝脏与胃溃疡局部粘连,粘连部位肝细胞出现了变性、坏死,糖元和核糖核酸减少至消失;还可见肝细胞再生及少量肉芽组织。本文结果提示胃溃疡时期肝脏参与了自身抗病过程。 | 张家口医学院87级组织学兴趣小组 | 1997 | 神经药理学报1997，0，3： | 0 |
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