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| 1 | Second-look surgery plus hyperthermic intraperitoneal chemotherapy for patients with colorectal cancer at high risk of peritoneal carcinomatosis:Does it really save lives?显示文摘The treatment of peritoneal carcinomatosis (PC) of colorectal origin with cytoreductive surgery(CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has a 5-year recurrence-free or cure rate of at least 16%, so it is no longer labeled as a fatal disease, and offers prolonged survival for patients with a low peritoneal carcinomatosis index. Metachronous PC of colorectal origin is so predictable that there is a model which has been used to successfully determine the individual risk of each patient. Patients at risk are clearly identified; those with the highest risk have small peritoneal nodules present in the first surgery (70% probability of developing PC), ovarian metastases(60%), perforated tumor onset or intraoperative tumor rupture(50%). Current clinical, biological and imaging techniques still lack sufficient sensitivity to diagnose PC in its initial stages, when CRS plus HIPEC has a greater impact and a higher cure rate. Second-look surgery with HIPEC or prophylactic HIPEC at the time of the first intervention have been proposed as means of preventing and/or anticipating clinical or radiological relapse in at-risk patients. Both techniques have shown a significant decrease in peritoneal relapses and should be considered essential weapons in the management of colorectal cancer. | Delia Cortes-Guiral Dominique Elias Pedro Antonio Cascales-Campos Alfredo Badía Yébenes Ismael Guijo Castellano Ana Isabel León Carbonero JoséIgnacio Martín Valadés Jesus Garcia-Foncillas Damian Garcia-Olmo | 2017 | World Journal of Gastroenterology2017，23，3： | 3 |
| 2 | ECG after near-drowning mimicking acute coronary syndrome with left main coronary artery involvement显示文摘We present the case of a 74-year-old man with diabetes and hypertension who had to be rescued owing to a near-drowning syndrome at sea.When he was rescued,he complained of dyspnea and chest pain.An electrocardiogram(ECG)suggested acute coronary syndrome(ACS)affecting the left main coronary artery.Therefore,he was referred to our hospital for urgent coronary angiography. | Alfredo Vidal García Javier Lacunza Ruiz José María Lpez Ayala Mariano Valdés | 2013 | World Journal of Emergency Medicine2013，4，1： | 2 |
| 3 | ICP-MS for absolute quantification of proteins for heteroatom-tagged, targeted proteomics显示文摘 | Alfredo Sanz-Medel María Montes-Bayón J?rg Bettmer M. Luisa Fernández-Sanchez Jorge Ruiz Encinar | 2012 | Trends in Analytical Chemistry2012，，： | 1 |
| 4 | Platelet glycoprotein IIIA PIA1/A2 polymorphism in young patients with ST elevation myocardial infarction and idiopathic ischemic stroke显示文摘 | Blanca Elsa Rivera-García Juan Carlos Esparza-García Jose Luis Aceves-Chimal Alfredo Lea?os-Miranda Abraham Majluf-Cruz Irma Isordia-Salas | 2013 | Molecular and Cellular Biochemistry (-)2013，，1： | 1 |
| 5 | Incidence of pertussis in persons < 15 years of age in Valencia, Spain: seroprevalence of antibodies to pertussis toxin (PT) in children, adolescents and adults 显示文摘 | Javier Diez-Domingo Alfredo Ballester Jose'-Marl'a Baldo | 2004 | Journal of Infection2004，49，3： | 1 |
| 6 | Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients显示文摘 | Alejandro G Eduardo A Alfredo R | 2003 | J Clin Endcorinol Metab2003，88，11： | 1 |
| 7 | Knize, MARINA L Chiarappa-Zucca, et al, Biodegradation of Potential Diesel Oxygenate Additives: dibutyl maleate (DMB) ,and tripropylene glycol methyl ether(TGME) 显示文摘 | ALFREDO A Marchetti MARK G | 2003 | Chemosphere2003，52，： | 1 |
| 8 | Re - engineering the toilet for sustainable wastewater management 显示文摘 | Tove AL Irene P Alfredo A | 2001 | ES&T2001，35，9： | 1 |
| 9 | Physical changes during active and passive composting of beef feedlot manure in winter and summer显示文摘 | Francis J Larney Andrew F Olson Alfredo A Carcamo | 2000 | Bioresouce technology2000，75，： | 1 |
| 10 | CD99 is expressed in chor- doid glioma and suggests ependymal origin显示文摘 | Alfredo E Romero-Rojas Julio A | 2012 | Virchows Arch2012，460，1： | 1 |
| 11 | Rebound Tonometer Compared With Goldmann Tonometer in Normal and Pathologic Corneas显示文摘 | Javier Moreno-Monta?és Noelia García Ana Fernández-Hortelano Alfredo García-Layana | 2007 | Cornea2007，，4： | 1 |
| 12 | Coal blend combustion: Link between unbumt carbon in fly ashes and maceral composition显示文摘 | SONIA H ALFREDO G GUILLERMO A XIMENA G CLAUDIA U | 2003 | Fuel Process Technol2003，80，3： | 1 |
| 13 | On-line dead-time compen- sation technique for open-loop PWM-VSI drives显示文摘 | ALFREDO R MU THOMAS A LIPO | 1999 | IEEE Trans- actions on Power Electronics1999，14，4： | 1 |
| 14 | Respiratory syncytial virus infection : a decade of contributions 显示文摘 | Val Blanco del Alfredo Jos e Mar f a Eiros Bouza Agust f n M? | 2012 | Le Infezioni in Medicina2012，，3： | 1 |
| 15 | Trichoderma research in the genome era显示文摘 | Prasun K M Benjamin A H Alfredo H | 2013 | Annual Review of Phytopathology2013，51，： | 1 |
| 16 | Identification and characterization of four splicing variants of ovine POU1F1 gene显示文摘 | Estela B Silvia A Alfredo C | 2006 | Gene2006，382，： | 1 |
| 17 | Odor and chemesthesis from exposures to glutaraldehyde vapor 显示文摘 | William S C Roland Sehmidt Alfredo A | 2007 | Int Arch Occup Environ Health2007，80，： | 1 |
| 18 | The pros and cons of dry gas seals installation in an existing synthesis gas compressor显示文摘 | Borba Alfredo Jose G A Borges | 2007 | Ammonia Plant Safety and Related Facilities2007，48，： | 1 |
| 19 | Economic freedom and the quality of life:an empirical analysis显示文摘 | Alfredo G E Peter A Z | 1999 | Constitutional Political Economy1999，10，2： | 1 |
| 20 | A new induction motor V/f control method capable of high-performance regulation at low speeds显示文摘 | Alfredo M G Thomas A L Donald W N | 1998 | IEEE Transactions on Industry Applications1998，34，4： | 1 |
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