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229篇 您的检索式:作者名="ALTENBURG"
    题名 作者 年代 出处 被引量
1Increased Filamentous Growth of Candida albicans in Simulated Microgravity显示文摘Knowledge of simulated microgravity (SMG)-induced changes in the pathogenicity of microorganisms is important for success of long-term spaceflight. In a previous study using the high aspect ratio vessel bioreactor, we showed that the yeast species Saccharomyces cerevisiae underwent a significant phenotypic response when grown in modeled microgravity, which was reflected in the analysis of gene expression profiles. In this study, we establish that Candida albicans responds to SMG in a similar fashion, demonstrating that there is a conserved response among yeast to this environmental stress. We also report that the growth of C. albicans in SMG results in a morphogenic switch that is consistent with enhanced pathogenicity. Specifically, we observed an increase in filamentous forms of the organism and accompanying changes in the expression of two genes associated with the yeast-hyphal transition. The morphological response may have significant implications for astronauts' safety, as the fungal pathogen may become more virulent during spaceflight.Sara D. Altenburg Sheila M. Nielsen-Preiss Linda E. Hyman 2008Genomics, Proteomics & Bioinformatics2008,6,1:3
2Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action显示文摘Faust M Altenburger R Backhaus T 2003Aquatic Toxicology2003,63,1:2
3Cleanli- ness of dentinal tubules following gutta-percha removal with and without solvents: A seanning eleetrnn mieroseopic study 显示文摘Horvalh SD Altenburger M J Naumann M 2009lnt EndndJ2009,42,11:1
4Synergisms with mixtures of xenoestrogens: a reevaluation using the method of isoboles 显示文摘KORTENKAMP A ALTENBURGER R 1998Sci Total Environ1998,221,:1
5Toxicity testing with Vibrio fischeri:A comparison between the long term(24 h)and the short term(30 min)bioassay显示文摘Backhaus T Froehner K Altenburger R 0,,12:1
6Modeling photoinduced algal toxicity of PAHs显示文摘Grote M Schuurmann G Altenburger R 2005Environ Sci Technol2005,39,11:1
7Thermal degradation of polyurethanes based on MDI: characteristic rela tionships between the decomposition parameters显示文摘Pielichowski K Pielichowski J Altenburg H 1996Thermo chim Acta1996,284,:1
8Water quality objectives for mixtures of toxic chemicals:problems and perspectives 显示文摘Vighi M Altenburger R Arrhenius A 2003Ecotoxieol Environ Saf2003,54,:1
9On the mode of action of N-Phenyl-2-naphthylamine in plants显示文摘Altenburger R Brack W Greco W R 2006Environ Sci Technol2006,40,19:1
10Plane-wave analysis of acoustic signals in a sandy sediment显示文摘Altenburg R A Chotiros N P Faulkner C M 1991JASA1991,89,1:1
11CCRSDelta32 protein expression and stability are critical for resistance to HIV-1 in vivo 显示文摘Agrawal L Jin Q Altenburg J 2007J Virol2007,81,13:1
12Ocular involvement in Adamantiades-Behcet's disease in Berlin,Germany显示文摘Krause L K(o)hler AK Altenburg A 0,,:1
13In vivo comparison of working length determination with two electronic apex locators 显示文摘Wrbas K T Ziegler A A Altenburger M J 2007Int Endod J2007,40,2:1
14Radiological central vein treatment in vascular access显示文摘Mansour M Kamper L Altenburg A 2008The journal of vascular access2008,9,2:1
15pH-dependent sorption,bioconcentration and algal toxicity of sulfonylurea herbicides显示文摘FAHL G M KREFT L ALTENBURGER R 1995Aquatic Toxicology1995,31,2:1
16Extrapolation concepts for dealing with multiple contamination in environmental risk assessment显示文摘Altenburger R Greco WR 2009Integrated Environmental Assessment and Management2009,5,1:1
17The Treatment of Chronic Recurrent Oral Aphthous Ulcers显示文摘Altenburg A El-Haj N Micheli C 2014Dtsch Arztebl Int2014,111,66:1
18Useful hydroxylamine derivatives for the synthesis of hydroxamic acids 显示文摘Altenburger J M Mioskowski C 1992Tetrahedron Letters1992,33,35:1
19Docosahexaenoic acid downregulates interferon gamma-induced expression of CXCL16 in human aortic smooth muscle cells显示文摘Altenburg JD Siddiqui RA 0,,01:1
20Predictability of the toxieity of multiple chemical mixtures to Vibrio fiseheri: mixtures composed of similarly acting chemicals 显示文摘Altenburger R Baekhaus T Boedeker W 2000Environmental Toxieolology and Chemistry2000,19,:1
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