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| 1 | Enteral stents for the management of malignant colorectal obstruction显示文摘Colorectal cancer(CRC) is the 3rd most common cancer in the United States with more than 10000 new cases diagnosed annually. Approximately 20% of patients with CRC will have distant metastasis at time of diagnosis, making them poor candidates for primary surgical resection. Similarly, 8%-25% of patients with CRC will present with bowel obstruction and will require palliative therapy. Emergent surgical decompression has a high mortality and morbidity, and often leads to a colostomy which impairs the patient's quality of life. In the last decade, there has been an increasing use of colonic stents for palliative therapy to relieve malignant colonic obstruction. Colonic stents have been shown to be effective and safe to treat obstruction from CRC, and are now the therapy of choice in this scenario. In the setting of an acute bowel obstruction in patients with potentially resectable colon cancer, stents may beused to delay surgery and thus allow for decompression, adequate bowel preparation, and optimization of the patient's condition for curative surgical intervention. An overall complication rate(major and minor) of up to 25% has been associated with the procedure. Long term failure of stents may result from stent migration and tumor ingrowth. In the majority of cases, repeat stenting or surgical intervention can successfully overcome these adverse effects. | Jeremy Kaplan Anna Strongin Douglas G Adler Ali A Siddiqui | 2014 | World Journal of Gastroenterology2014，20，37： | 13 |
| 2 | Endoscopic retrograde cholangiopancreatography in cirrhosis-a systematic review and meta-analysis focused on adverse events显示文摘AIM To investigate indications and outcomes of endoscopic retrograde cholangiopancreatography(ERCP) in cirrhotics, especially adverse events. Patients with cirrhosis undergoing ERCP are believed to have increased risk. However, there is a paucity of literature describing the indications and outcomes of ERCP procedures in patients with cirrhosis, especially focusing on adverse events.METHODS We performed a systematic appraisal of major literature databases, including PubMed and EMBASE, with a manual search of literature from their inception until April 2017.RESULTS A total of 6,505 patients from 15 studies were analyzed(male ratio 59%, mean age 59 years), 11% with alcoholic and 89% with non-alcoholic cirrhosis, with 56.2% Child-Pugh class A, and 43.8% class B or C. Indications for ERCP included choledocholithiasis 60.9%, biliary strictures 26.2%, gallstone pancreatitis 21.1% and cholangitis 15.5%. Types of interventions included endoscopic sphincterotomy 52.7%, biliary stenting 16.7% and biliary dilation 4.6%. Individual adverse events included hemorrhage in 4.58%(95%CI: 2.77-6.75%, I^2 = 85.9%), post-ERCP pancreatitis(PEP) in 3.68%(95%CI: 1.83-6.00%, I^2 = 89.5%), cholangitis in 1.93%(95%CI: 0.63-3.71%, I^2 = 87.1%) and perforation in 0.00%(95%CI: 0.00-0.23%, I^2 = 37.8%). Six studies were used for comparison of ERCPrelated complications in cirrhosis vs non-cirrhosis, which showed higher overall rates of complications in cirrhosis patients with pooled OR of 1.63(95%CI: 1.27-2.09, I2 = 65%): higher rates of hemorrhage with OR of 2.05(95%CI: 1.62-2.58, I^2 = 2.1%) and PEP with OR of 1.33(95%CI: 1.04-1.70, I2=65%), but similar cholangitis rates with OR of 1.23(95%CI: 0.67-2.26, I^2 = 44.3%).CONCLUSION There is an overall higher rate of adverse events related to ERCP in patients with cirrhosis, especially hemorrhage and PEP. A thorough risk/benefit assessment should be performed prior to undertaking ERCP in patients with cirrhosis. | Shailender Singh Mashiana Amaninder Singh Dhaliwal Harlan Sayles Banreet Dhindsa Ji Won Yoo Qing Wu shailender singh Ali A Siddiqui Gordon Ohning Mohit Girotra Douglas G Adler | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，11： | 6 |
| 3 | Ca^2+ /calmodulin regulates salicylic-add-mediated plant immunity显示文摘 | Du L Ali G S Smons K A | 2009 | Nature2009，457，： | 1 |
| 4 | Swine influenza H1N1 virus induces acute inflammato- ry immune responses in pig lungs: a potential animal model for human H1N1 influenza virus显示文摘 | Khatri M Dwivedi V Krakowka S Manickam C Ali A Wang L Qin Z Renukaradhya G J Lee C W | 2010 | J Virol2010，84，11： | 1 |
| 5 | Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy显示文摘 | Levent G Ali A Ahmet A | 2006 | Translate Med2006，4，1： | 1 |
| 6 | Interactions of some Schiff base compounds with mild steel surface in hydrochloric acid solution显示文摘 | Emel Bayol Tijen G i rten Ali G rten A | 2008 | Materials Chemistry and Physics2008，，6： | 1 |
| 7 | 显示文摘 | Yahaya G O Ahdab A A Ali S A | 2001 | Polymer2001，42，： | 1 |
| 8 | The Nonallergic Asthma of Obesity A Matter of Distal Lung Compliance显示文摘 | Ali A A Bates J H T Chapman D G | 2014 | Am J Respir Crit Care Med2014，189，12： | 1 |
| 9 | Body massindex is independently associated with hospital mortality in me chanicallv ventilated adults with acute lung injurr显示文摘 | O’BRIEN J M PHILLIPS G S ALI N A | 2006 | CriticalCare Medicine2006，34，3： | 1 |
| 10 | Dual Doped High Tg White Organic Light Emitting Devices on Silicon显示文摘 | Ali T A Jones G W Howard W E | 2004 | SID2004，29，： | 1 |
| 11 | The Mechanism of 2,4- dichlorophenoxyacetic acid neurotoxicity on rat brain tissue by using FTIR spectroscopy显示文摘 | Raouf G A Qusti S Y Ali A M | 2012 | Life Sci J2012，9，4： | 1 |
| 12 | Quantum discord for two-qubit X states显示文摘 | M Ali A R P Rau G Alber | 2010 | Phys Rev A2010，81，04： | 1 |
| 13 | Heterologous expression of lignin peroxiedase of Phanerochaete chrysosporium in Aspergillus niger显示文摘 | A S Mohamed S Sami G Ali | 1999 | Biotechnology Letters1999，21，： | 1 |
| 14 | Absorption and Emission Properties of Ho^3+ Doped Lead-zinc-borate Glasses显示文摘 | Sooraj H N Ali N Dias A G | 2006 | Thin Solid Films2006，515，1： | 1 |
| 15 | Response to environ- mental stress, cell-wall integrity, and virulence are or- chestrated through the ealcineurin pathway in Ustilago hordei 显示文摘 | Cervantes J A Ali S Bakkeren G | 2011 | Molecular Plant-microbe Interactions2011，24，2： | 1 |
| 16 | CD56 expression of neuroendocflne neoplasms on immunophenotyping by flow eytometry:a novel diagnostic approaeh to fine-needle aspiration biopsy显示文摘 | Farinola M A Weir E G Ali S Z | | 0，，4： | 1 |
| 17 | In situ regulation of DC subsets and T cells mediates tumor regression in mice显示文摘 | Ali O A Emerieh D Dranoff G | 2009 | Sci Transl Med2009，1，： | 1 |
| 18 | An optimum transformation for somatic cell content ration in milk 显示文摘 | Ali A K A Shook G E | 1980 | J Dairy Sci1980，63，： | 1 |
| 19 | Simulation of plug flow fluidized bed dryers显示文摘 | Baker C G J Khan A R Ali Y I | 2006 | Chemical Engineering and Processing2006，45，8： | 1 |
| 20 | Solution behavior of hydrophobically associating water-soluble block copolymers of acrylam-ide and N-benzylacrylamide显示文摘 | Yahaya G O Ahdab A A Ali S A | 2001 | Polymer2001，，42： | 1 |
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