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您的检索式：作者名="ANTHONY CW TAM"
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| 1 | Molecular cloning and structural analysis of human norepinephrine transporter gene(NETHG)显示文摘A cDNA molecule encoding a major part of the hu-man Norepinephrine transporter(hNET) was synthesized by means of Polymerase Chain Reaction(PCR) technique and used as a probe for selecting the human genomic NET gene. A positive clone harbouring the whole gene was ob-tained from a human lymphocyte genomic library through utilizing the 'genomic walking' technique. The clone, des-ignated as phNET, harbours a DNA fragment of about 59 kb in length inserted into BamH Ⅰ site in cosmid pWE15.The genomic clone contains 14 exons encoding all amino acid residues in the protein. A single exon encodes a dis-tinct transmembrane domaill, except for transmembrane domain 10 and 11, which are encoded by part of two ex-ons respectively, and exon 12, which encodes part of do-main 11 and all of domain 12. These results imply that there is a close relationship between exon splicing of a gene and structural domains of the protein, as is the case for the human γ-aminobutyric acid transporter(hGAT) and a number of other membrane proteins. | GUO LIHE LIHUA ZHU FANG HUANG ANTHONY CW TAM ZENGCHAN YE JIAN FEI XIAOYONG ZHANG DOMINIC MAN-KIT LAM (Shanghai Institute of Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.)(Honq Kong Institute of Biotechnology, Shatin, NT,Hong Ko | 1995 | Cell Research1995，5，1： | 0 |
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