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| 1 | Incidence and risk factors for the development of anemia following gastric bypass surgery显示文摘AIM:To evaluate the incidence and risk factors for the development of anemia after RouxenY gastric bypass (RYGB).METHODS: A retrospective analysis of patients undergoing RYGB from January 2003 to November 2007 was performed. All patients had a preoperative body mass index > 40 kg/m2. A total of 206 patients were evaluated. All patients were given daily supplements of ferrous sulfate tablets for 2 wk following their operation. Hematological and metabolic indices were routinely evaluated following surgery. Patients were followed for a minimum of 86 wk.RESULTS: There were 41 males and 165 females with an average age of 40.8 years. 21 patients (10.2%) developed postoperative anemia and 185 patients (89.8%) did not. Anemia was due to iron deficiency in all cases. The groups had similar demographics, surgical procedure and comorbidities. Menstruation (P = 0.02) and peptic ulcer disease (P = 0.01) were risk factors for the development of postoperative anemia.CONCLUSION: Iron deficiency anemia is frequent. RYGB surgery compounds occult blood loss. Increased ferrous sulfate supplementation may prevent iron depletion in populations at increased risk. | Dimitrios V Avgerinos Omar H Llaguna Matthew Seigerman Amanda J Lefkowitz I Michael Leitman | 2010 | World Journal of Gastroenterology2010，16，15： | 6 |
| 2 | Interferon-a plus lamivudine vslamivudine reduces breakthroughs, but does not affect sustained response in HBeAg negative chronic hepatitis B显示文摘AIM: To investigate the efficacy of combination treatment of IFN-α and lamivudine compared to lamivudine monotherapy, after 24 mo of administration in HBeAg-negative hepatitis B patients.METHODS: Fifty consecutive patients were randomly assigned to receive IFN-α-2b (5 MU thrice per week, n = 24) plus lamivudine (100 mg daily) or lamivudine only (n = 26) for 24 mo. Patients were followed up for further 6 mo. The primary outcome was the proportion with sustained virological response (undetectable serum HBV DNA concentrations) and or sustained biochemical response (transaminase levels within normal range) at 30 mo (6 mo after the end of therapy). Secondary end-points were timed from initial virological (biochemical) response to VBR (BBR, respectively) and the emergence of YMDD mutants across the two arms.RESULTS: Five of twenty-four (21%) patients in the combination arm vs 3/26 (12%) in the lamivudine arm had sustained response (i.e., normal serum transaminase levels and undetectable HBV DNA by PCR assay) 6 mo after treatment discontinuation. A reduction in the emergence of YMDD mutants and in the development of virological breakthroughs was observed in patients receiving combination treatment (10% vs46%, P= 0.01 and 14% vs46%, P= 0.03,respectively).Time from initial virologic response to virologic breakthrough (VBR) was greater among initial responders receiving combination treatment compared to those receiving lamivudine (22.9 mo vs 15.9 mo, respectively; P = 0.005).CONCLUSION: Our results demonstrate that IFN-α plus lamivudine combination therapy does not increase the sustained response, compared to lamivudine. However,combination therapy reduces the likelihood of VBR due to YMDD mutants and prolongs the time period until the breakthrough development. | Michalis Economou Spilios Manolakopoulos Thomas A Trikalinos Spyros Filis Sotiris Bethanis Dimitrios Tzourmakliotis Alec Avgerinos Sotiris Raptis Epameinondas V Tsianos | 2005 | World Journal of Gastroenterology2005，11，37： | 6 |
| 3 | Management of endoscopic retrograde cholangio- pancreatography: related duodenal perforations 显示文摘 | Avgerinos D V Llaguna O H Lo A Y Voli J Leitman I M | 2009 | Surg Endosc2009，23，： | 1 |
| 4 | Measurement of the resistive leakage current in surge arresters under artifieial rain test and impulse voltage subjection显示文摘 | Christodoulou C A Avgerinos M V Ekonomou L | 2009 | IET Science Measurement and Technology2009，3，3： | 1 |
| 5 | A shortcourse of preoperative radiotherapy improves prognosis of op-erable rectal carcinoma:a case control study显示文摘 | Penopoulos V Handolias M Avgerinos A | 2008 | Hepatogas-troenterology2008，55，85： | 1 |
| 6 | Incidence and risk factors for the development of incisional hernia following elective laparoscopic versus open colon resections 显示文摘 | Llaguna O H Avgerinos D V Lugo J Z | 2010 | Am J Surg2010，200，2： | 1 |
| 7 | A short course of preoperative radiotherapy improves prognosis of operable rectal car- cinoma: a case control study显示文摘 | Penopoulos V Handolias M Avgerinos A | 2008 | Hepatogastroenterology2008，55，85： | 1 |
| 8 | Numerical validation of analytical solutions and their use for equivalent-linear seismic analysis of circular tunnels显示文摘 | KONTOE S AVGERINOS V POTTS DM | 2014 | Soil Dynamics and Earthquake Engineering2014，66，： | 1 |
| 9 | Rapid right ventricular pacing for balloon valvuloplasty in congenital aortic stenosis:A systematic review显示文摘BACKGROUND Balloon aortic valvuloplasty(BAV)is a well-established treatment modality for congenital aortic valve stenosis.AIM To evaluate the role of rapid right ventricular pacing(RRVP)in balloon stabilization during BAV on aortic regurgitation(AR)in pediatric patients.METHODS A systematic review of the MEDLINE,Cochrane Library,and Scopus databases was conducted according to the PRISMA guidelines(end-of-search date:July 8,2020).The National Heart,Lung,and Blood Institute and Newcastle-Ottawa scales was utilized for quality assessment.RESULTS Five studies reporting on 72 patients were included.The studies investigated the use of RRVP-assisted BAV in infants(>1 mo)and older children,but not in neonates.Ten(13.9%)patients had a history of some type of aortic valve surgical or catheterization procedure.Before BAV,58(84.0%),7(10.1%),4(5.9%)patients had AR grade 0(none),1(trivial),2(mild),respectively.After BAV,34(49.3%),6(8.7%),26(37.7%),3(4.3%),patients had AR grade 0,1,2,and 3(moderate),respectively.No patient developed severe AR after RRVP.One(1.4%)developed ventricular fibrillation and was defibrillated successfully.No additional arrhythmias or complications occurred during RRVP.CONCLUSION RRVP can be safely used to achieve balloon stability during pediatric BAV,which could potentially decrease AR rates. | Konstantinos S Mylonas Ioannis A Ziogas Charitini S Mylona Dimitrios V Avgerinos Christos Bakoyiannis Fotios Mitropoulos Aphrodite Tzifa | 2020 | World Journal of Cardiology2020，12，11： | 0 |
| 10 | Frailty in patients undergoing transcatheter aortic valve replacement:from risk scores to frailty-based management显示文摘Aortic stenosis(AS)is the most common valvular disease in the western coun-tries and is associated with aging.[1,2]Transcatheter aortic valve replacement(TAVR)now offers a therapeutic option for elderly patients who are deemed inoperable and is an excellent alternative for those who are considered high-risk for surgical valve replacement.[3,4]However,mortality after TAVR is still high with one-year and two-year mortality rates of 24.3%and 33.9%,respectively.[5]Thus,util-ization of effective risk stratification tools before TAVR cannot be overstated. | Andreas Tzoumas Damianos G.Kokkinidis Stefanos Giannopoulos George Giannakoulas Leonidas Palaiodimos Dimitrios V Avgerinos Polydoros N Kampaktsis Robert T.Faillace | 2021 | Journal of Geriatric Cardiology2021，18，6： | 0 |
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