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| 1 | Does a combined intervention program of repetitive transcranial magnetic stimulation and intensive occupational therapy affect cognitive function in patients with post-stroke upper limb hemiparesis?显示文摘Low-frequency repetitive transcranial magnetic stimulation(LF-r TMS) to the contralesional hemisphere and intensive occupational therapy(i OT) have been shown to contribute to a significant improvement in upper limb hemiparesis in patients with chronic stroke. However, the effect of the combined intervention program of LF-r TMS and i OT on cognitive function is unknown. We retrospectively investigated whether the combined treatment influence patient's Trail-Making Test part B(TMT-B) performance, which is a group of easy and inexpensive neuropsychological tests that evaluate several cognitive functions. Twenty-five patients received 11 sessions of LF-r TMS to the contralesional hemisphere and 2 sessions of i OT per day over 15 successive days. Patients with right- and left-sided hemiparesis demonstrated significant improvements in upper limb motor function following the combined intervention program. Only patients with right-sided hemiparesis exhibited improved TMT-B performance following the combined intervention program, and there was a significant negative correlation between Fugl-Meyer Assessment scale total score change and TMT-B performance. The results indicate the possibility that LF-r TMS to the contralesional hemisphere combined with i OT improves the upper limb motor function and cognitive function of patients with right-sided hemiparesis. However, further studies are necessary to elucidate the mechanism of improved cognitive function. | Takatoshi Hara Masahiro Abo Kiyohito Kakita Takeshi Masuda Ryunosuke Yamazaki | 2016 | Neural Regeneration Research2016，11，12： | 18 |
| 2 | Usefulness of noninvasive transient elastography for assessment of liver fibrosis stage in chronic hepatitis C显示文摘AIM:To evaluate the method of noninvasive transient elastography for assessment of histological stage of liver fibrosis in patients with chronic hepatitis C (CHC). METHODS: Two hundred and thirty-seven patients with CHC were included in this study. Liver biopsy was performed under ultrasonography on 217 of the patients, excluding twenty with clear clinical evidence of liver cirrhosis. Fifty subjects without liver disease were enrolled as a control group (stage 0). Twenty- five patients with sustained virological response (SVR) to interferon (IFN) therapy were also enrolled. These patients underwent liver biopsy before IFN therapy. Examination of liver stiffness (LS) was performed by elastography. RESULTS: Medians (50% levels) of LS were 4.1 (3.5-4.9), 6.3 (4.8-8.5), 8.8 (6.8-12.0), 14.6 (10.5-18.6), and 22.2 (15.4-28.0), respectively, in the fibrosis stages 0-4 (P < 0.001). LS was significantly correlated with four serum fibrosis markers. LS values in patients with SVR were 3.8 (3.5-5.6), 5.2 (4.4-6.8), 6.8 (6.1-7.6), and 6.1 (3.6-7.9), respectively, in the fibrosis stages 1-4. In all stages, LS for patients with SVR was significantly lower than that for patients who did not undergo IFN therapy. LS was significantly correlated with serum concentrations of hyaluronic acid, type Ⅳ collagen, type Ⅳ collagen 7S, and type Ⅲ procollagen N peptide. CONCLUSION: LS correlated well with the histologicalstage of fibrosis. Changes in liver fibrosis stage may thus be estimated noninvasively using transient elastography. | Tadashi Takeda Takahiro Yasuda Yuji Nakayama Mika Nakaya Megumi Kimura Mariko Yamashita Ayumi Sawada Koji Abo Setsuko Takeda Hiroki Sakaguchi Susumu Shiomi Hitoshi Asai Shuichi Seki | 2006 | World Journal of Gastroenterology2006，12，48： | 16 |
| 3 | Obesity, metabolic syndrome and diabetic retinopathy: Beyond hyperglycemia显示文摘Diabetic retinopathy(DR) is the most feared ocular manifestation of diabetes. DR is characterized by progressive retinal damage that may eventually result in blindness. Clinically, this blindness is caused by progressive damage to the retinal microvasculature, which leads to ischemia, retinal swelling, and neovascularization. Retinopathy is associated with both type 1 and type 2 diabetes, with DR being the leading cause of new onset blindness in United States adults. Despite this strong association with diabetes, it must be noted that the development of retinopathy lesions is multifactorial and may occur in individuals without an established history of diabetes. Metabolic syndrome is a multifactorial condition of central obesity, hypertriglyceridemia, dyslipidemia, hypertension, fasting hyperglycemia, and insulin resistance. Although several studies examined the individual components observed in the metabolic syndrome in relation to the development of DR, there is conflicting data as to the association of the metabolic syndrome with the development of retinopathy lesions in nondiabetic subjects. This review will summarize the current literature on the evidence of the metabolic syndrome on retinopathy in subjects with and without an established history of diabetes. This review will also discuss some of the mechanisms through which metabolic syndrome can contribute to the development of retinopathy. | Osinakachukwu Mbata Nada Fawzy Abo El-Magd Azza Bahram El-Remessy | 2017 | World Journal of Diabetes2017，8，7： | 16 |
| 4 | 无线电掩星和激光雷达观测结果比较显示文摘简要阐述了激光雷达和GPS掩星探测大气的基本原理,并利用1996年10月14日1625 UT时 B本 TMU钠和瑞利散射激光雷B(39.23°E、 35.37°N)资#,反演得到 30-55 km高度范围内大气密度和温度的观测结果,与此同时通过激光雷达上空的 GPS掩星观测到的掩星切点处的观测结果进行了比较.结果表明:两种方法获得测出的密度廓线符合得很好;温度廓线的变化趋势也基本一致,但在某些高度上有较大的偏离.文中最后对比较结果作了简要分析,讨论了重力波对大气密度和温度廓线的影响. | 曾桢 胡雄 张训械 Makoto Abo | 2001 | 空间科学学报2001，21，2： | 14 |
| 5 | Closed-loop hydrometallurgical treatment of end-of-life lithium ion batteries: Towards zero-waste process and metal recycling in advanced batteries显示文摘This work presents an enhanced hydrometallurgical process for recycling lithium ion batteries. First, endof-life batteries were processed in a physical pre-treatment plant to obtain a representative electrode material. The resulting leachate was purified forth by iron-precipitation, liquid–liquid extractions, and an innovative Li–Na separation, in order to obtain valuable products. These products include high-grade graphite, cobalt oxide(Co3O4, purity 83%), cobalt oxalate(CoC2O4, purity 96%), nickel oxide(Ni O, purity89%), and lithium carbonate(Li2CO3, purity 99.8%). The recovery rate was quantitative for graphite, between 80% and 85% for cobalt depending on the nature of the recovery method, 90% for nickel, and 72%for lithium. Secondary streams were also valorized to obtain sodium sulfate(Na2SO4, purity 96%), and MnCoFe2O4 magnetic nano-sorbents according to the zero-waste concept. In order to close the loop, recycled Co3O4 and NiO were used as conversion-type anode materials for advanced lithium ion batteries showing promising performances. | Thomas Abo Atia Giuseppe Elia Robert Hahn Pietro Altimari Francesca Pagnanelli | 2019 | Journal of Energy Chemistry2019，28，8： | 8 |
| 6 | Relationship between microvessel count and post-hepatectomy survival in patients with hepatocellular carcinoma显示文摘AIM: To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our preliminary study. METHODS: We examined relationships between MVC and clinicopathological factors in 128 HCC patients. The modifi ed Japan Integrated Staging score (mJIS) was applied to examine subsets of HCC patients. RESULTS: Median MVC was 178/mm^2, which was used as a cut-off value. MVC was not signif icantly associated with any clinicopathologic factors or postoperative recurrent rate. Lower MVC was associated with poor disease-free and overall survivals by univariate analysis (P = 0.039 and P = 0.087, respectively) and lower MVC represented an independent poor prognostic factor in disease-free survival by Cox’s multivariateanalysis (risk ratio, 1.64; P = 0.024), in addition to tumor size, vascular invasion, macroscopic fi nding and hepatic dysfunction. Signifi cant differences in disease-free and overall survivals by MVC were observed in HCC patients with mJIS 2 (P = 0.046 and P = 0.0014, respectively), but not in those with other scores. CONCLUSION: Tumor MVC appears to offer a useful prognostic marker of HCC patient survival, particularly in HCC patients with mJIS 2. | Atsushi Nanashima Toshiyuki Nakayama Yorihisa Sumida Takafumi Abo Hiroaki Takeshita Kenichirou Shibata Shigekazu Hidaka Terumitsu Sawai Toru Yasutake Takeshi Nagayasu | 2008 | World Journal of Gastroenterology2008，14，31： | 7 |
| 7 | Endoscopic naso-pancreatic drainage for the treatment of pancreatic fistula occurring after LDLT显示文摘Pancreatic fistula is a quite rare complication in patients who undergo living donor liver transplantation(LDLT).However,in the cases that show pancreatic fistula,the limited volume of the graft and the resultant inadequate liver function may complicate the management of the fistula.As a result,the pancreatic fistula may result in the death of the patient.We present 2 cases in whichendoscopic treatment was effective against pancreatic fistulas that developed after LDLT.In case 1,a 61-yearold woman underwent LDLT for primary biliary cirrhosis.Because of a portal venous thrombus caused by a splenorenal shunt,the patient underwent portal vein reconstruction,and a splenorenal shunt was ligated on postoperative day(POD)7.The main pancreatic duct was injured during the manipulation to achieve hemostasis,thereby necessitating open drainage.However,discharge of pancreatic fluid continued even after POD 300.Endoscopic naso-pancreatic drainage(ENPD)was performed,and this procedure resulted in a remarkable decrease in drain output.The refractory pancreatic fistula healed on day 40 after ENPD.In case 2,a 58-year-old man underwent LDLT for cirrhosis caused by the hepatitis C virus.When the portal vein was exposed during thrombectomy,the pancreatic head was injured,which led to the formation of a pancreatic fistula.Conservative therapy was ineffective;therefore,ENPD was performed.The pancreatic fistula healed on day 38 after ENPD.The findings in these 2 cases show that endoscopic drainage of the main pancreatic duct is a less invasive and effective treatment for pancreatic fistulas that develop after LDLT. | Akihisa Nagatsu Toshiya Kamiyama Satoru Todo Masahiko Taniguchi Tomomi Suzuki Hiroyuki Furukawa Tsuyoshi Shimamura Kenichiro Yamashita Hiroshi Kawakami Daisuke Abo | 2011 | World Journal of Gastroenterology2011，17，30： | 5 |
| 8 | Robot-assisted radical cystectomy and intracorporeal orthotopic neobladder: 1-year functional outcomes显示文摘Complete intracorporeal urinar y diversion(ICUD)with an orthotopic neobladder is an emerging procedure.The objective of this article was to assess retrospectively the urodynamic and continence results after robot-assisted radical cystectomy(RARC)and ICUD with a modified orthotopic Studer neobladder.After a median follow-up time of 11 months,all patients were socially continent(≤1 pad)at daytime.Median Pouch capacity was 404 ml with a median postvoid residual volume of 0 ml.All patients stated that they would choose the same type of urinary diversion again.RARC and ICUD with orthotopic neobladder provides promising functional and urodynamic results with high patient satisfaction. | Fabian Obrecht Nadim Abo Youssef Orlando Burkhardt Christoph Schregel Marco Randazzo Christian Padevit Peter Wiklund Hubert John | 2020 | Asian Journal of Andrology2020，22，2： | 4 |
| 9 | Helicobacter pylori may be an initiating factor in newly diagnosed ulcerative colitis patients: A pilot study显示文摘AIM To directly visualize Helicobacter pylori(H. pylori) by the highly sensitive and specific technique of immunohistochemical staining in colonic tissue from patients newly diagnosed with ulcerative colitis(UC).METHODS Colonoscopic biopsies from thirty patients with newly diagnosed UC and thirty controls were stained with Giemsa stain and immunohistochemical stain for detection of H. pylori in the colonic tissue. Results were confirmed by testing H. pylori Ag in the stool then infected patients were randomized to receive either anti H. pylori treatment or placebo.RESULTS Twelve/30(40%) of the UC patients were positive for H. pylori by Giemsa, and 17/30(56.6%) by immunohistochemistry stain. Among the control group 4/30(13.3%) and 6/30(20 %) were positive for H. pylori by Giemsa and immunohistochemistry staining respectively. H. pylori was significantly higher in UC than in controls(P = 0.04 and 0.007). All Giemsa positive patients and controls were positive by immunohistochemical stain. Four cases of the control group positive for H. pylori also showed microscopic features consistent with early UC.CONCLUSION H. pylori can be detected in colonic mucosa of patients with UC and patients with histological superficial ulcerations and mild infiltration consistent with early UC. There seems to be an association between UC and presence of H. pylori in the colonic tissue. Whether this is a causal relationship or not remains to be discovered. | Loai Mansour Ferial El-Kalla Abdelrahman Kobtan Sherief Abd-Elsalam Mohamed Yousef Samah Soliman Lobna Abo Ali Walaa Elkhalawany Ibrahim Amer Heba Harras Maha M Hagras Mohamed Elhendawy | 2018 | World Journal of Clinical Cases2018，6，13： | 4 |
| 10 | ANFIS-based Sensor Fusion System of Sit-to-stand for Elderly People Assistive Device Protocols显示文摘This paper describes the analysis and design of an assistive device for elderly people under development at the EgyptJapan University of Science and Technology(E-JUST) named E-JUST assistive device(EJAD).Several experiments were carried out using a motion capture system(VICON) and inertial sensors to identify the human posture during the sit-to-stand motion.The EJAD uses only two inertial measurement units(IMUs) fused through an adaptive neuro-fuzzy inference systems(ANFIS) algorithm to imitate the real motion of the caregiver.The EJAD consists of two main parts,a robot arm and an active walker.The robot arm is a 2-degree-of-freedom(2-DOF) planar manipulator.In addition,a back support with a passive joint is used to support the patient s back.The IMUs on the leg and trunk of the patient are used to compensate for and adapt to the EJAD system motion depending on the obtained patient posture.The ANFIS algorithm is used to train the fuzzy system that converts the IMUs signals to the right posture of the patient.A control scheme is proposed to control the system motion based on practical measurements taken from the experiments.A computer simulation showed a relatively good performance of the EJAD in assisting the patient. | Omar Salah Ahmed A.Ramadan Salvatore Sessa Ahmed Abo Ismail Makasatsu Fujie Atsuo Takanishi | 2013 | International Journal of Automation and computing2013，10，5： | 4 |
| 11 | Behavior of raft on settlement reducing piles:Experimental model study显示文摘An experimental program is conducted on model piled rafts in sand soil.The experimental program is aimed to investigate the behavior of raft on settlement reducing piles.The testing program includes tests on models of single pile,unpiled rafts and rafts on 1,4,9,or 16 piles.The model piles beneath the rafts are closed ended displacement piles installed by driving.Three lengths of piles are used in the experiments to represent slenderness ratio,L/D,of 20,30 and 50,respectively.The dimensions of the model rafts are 30 cm×30 cm with different thickness of 0.5 cm,1.0 cm or 1.5 cm.The raft-soil stiffness ratios of the model rafts ranging from 0.39 to 10.56 cover flexible to very stiff rafts.The improvement in the ultimate bearing capacity is represented by the load improvement ratio,LIR,and the reductions in average settlement and differential settlement are represented by the settlement ratio,SR,and the differential settlement ratio,DSR,respectively.The effects of the number of settlement reducing piles,raft relative stiffness,and the slenderness ratio of piles on the load improvement ratio,settlement ratio and differential settlement ratio are presented and discussed.The results of the tests show the effectiveness of using piles as settlement reduction measure with the rafts.As the number of settlement reducing piles increases,the load improvement ratio increases and the differential settlement ratio decreases. | Basuony El-Garhy Ahmed Abdel Galil Abdel-Fattah Youssef Mohamed Abo Raia | 2013 | Journal of Rock Mechanics and Geotechnical Engineering2013，5，5： | 4 |
| 12 | Outcomes of gastrointestinal defect closure with an overthe-scope clip system in a multicenter experience: An analysis of a successful suction method显示文摘AIM To demonstrate the clinical outcomes of a multicenter experience and to suggest guidelines for choosing a suction method. METHODS This retrospective study at 5 medical centers involved 58 consecutive patients undergoing over-the-scope clips(OTSCs) placement. The overall rates of technical success (TSR), clinical success (CSR), complications, and procedure time were analyzed as major outcomes. Subsequently, 56 patients, excluding two cases that used the Anchor device, were divided into two groups: 14 cases of simple suction (SS-group) and 42 cases using the Twin Grasper (TG-group). Secondary evaluation was performed to clarify the predictors of OTSC success.RESULTS The TSR, CSR, complication rate, and median procedure time were 89.7%, 84.5%, 1.8%, and 8 (range 1-36) min, respectively, demonstrating good outcomes. However, significant differences were observed between the two groups in terms of the mean procedure time (5.9 min vs 14.1 min). The CSR of the SS- and TG-groups among cases with a maximum defect size ≤ 10 mm and immediate or acute refractory bleeding was 100%, which suggests that SS is a better method than TG in terms of time efficacy. The CSR in the SS-group (78.6%), despite the technical success of the SS method (TSR, 100%), tended to decrease due to delayed leakage compared to that in the TG-group (TSR, CSR; 88.1%), indicating that TG may be desirable for leaks and fistulae with defects of the entire layer. CONCLUSION OTSC system is a safe and effective therapeutic option for gastrointestinal defects. Individualized selection of the suction method based on particular clinical conditions may contribute to the improvement of OTSC success. | Hideki Kobara Hirohito Mori Shintaro Fujihara Noriko Nishiyama Taiga Chiyo Takayoshi Yamada Masao Fujiwara Keiichi Okano Yasuyuki Suzuki Masayuki Murota Yoshitaka Ikeda Makoto Oryu Mohamed Abo Ellail Tsutomu Masaki | 2017 | World Journal of Gastroenterology2017，23，9： | 3 |
| 13 | Lgr5 +ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro显示文摘 | Nick Barker Meritxell Huch Pekka Kujala Marc van de Wetering Hugo J. Snippert Johan H. van Es Toshiro Sato Daniel E. Stange Harry Begthel Maaike van den Born Esther Danenberg Stieneke van den Brink Jeroen Korving Arie Abo Peter J. Peters Nick Wright Richa | 2010 | Cell Stem Cell2010，，1： | 2 |
| 14 | Ethnobotanical studies of medicinal plants used in the management of diabetes mellitus in South Western Nigeria显示文摘 | K.A. Abo A.A. Fred-Jaiyesimi A.E.A. Jaiyesimi | 2007 | Journal of Ethnopharmacology2007，，1： | 2 |
| 15 | 餐厨垃圾直接发酵生产生物质丁醇的研究显示文摘为考察餐厨垃圾不糖化直接进行产丁醇发酵的可行性,优选高效利用淀粉产丁醇梭菌Clostridium saccharoperbutylacetonicum N1-4,并发现不同来源和构型的淀粉对发酵有影响,且直链淀粉更易于被利用。餐厨垃圾直接发酵比糖化发酵效率高,且可避免底物抑制。在固液比1∶1条件下,餐厨垃圾直接发酵丁醇产量达到12. 1 g/L,丁醇碳转化率为0. 402,最大生产速率为0. 705 g/(L·h);固液比1∶2条件下,直接发酵最大生产速率是糖化发酵的2. 05倍。餐厨垃圾发酵产丁醇,可在解决环境问题的同时,为丁醇生产提供廉价原材料。 | 王永林 高明 BODJUI Olivier Abo 王芳霞 汪群慧 | 2019 | 环境工程2019，37，4： | 2 |
| 16 | Eectrochemical enzymatic deoxygenation of chiral sulfoxides utilizing DMSO reductase显示文摘 | Abo M Dejima M | 2000 | Tetrahedron:Asymmetry2000，11，： | 2 |
| 17 | MicroRNAs as diagnostic markers for pancreatic ductal adenocarcinoma and its precursor, pancreatic intraepithelial neoplasm显示文摘 | Yue Xue Ahmad N. Abou Tayoun Kristine M. Abo J. Marc Pipas Stuart R. Gordon Timothy B. Gardner Richard J. Barth Arief A. Suriawinata Gregory J. Tsongalis | 2013 | Cancer Genetics2013，，： | 2 |
| 18 | Research on stress-induced apoptosis of natural killer cells and the alteration of their killing activity in mouse liver显示文摘AIM:To investigate the stress-induced apoptosis of natural killer(NK)cells and the changes in their killing activity in mouse livers.METHODS:A restraint stress model was established in mice.Flow cytometry was employed to measure the percentage of NK cells and the changes in their absolute number in mouse liver.The cytotoxicity of hepatic and splenic NK cells was assessed against YAC-1 target cells via a 4 h 51Cr-release assay.RESULTS:The restraint stress stimulation induced the apoptosis of NK cells in the liver and the spleen,which decreased the cell number.The number and percentage of NK cells in the spleen decreased.However,the number of NK cells in the liver decreased,whereas the percentage of NK cells was significantly increased.The apoptosis of NK cells increased gradually with prolonged stress time,and the macrophage-1(Mac-1)+NK cells were more susceptible to apoptosis than Mac-1-NK cells.Large numbers of Mac-1-NK cells in the liver,which are more resistant to stress-induced apoptosis,were observed than the Mac-1-NK cells in the spleen.The stress stimulation diminished the killing activity of NK cells in the spleen was significantly decreased,but the retention of numerous Mac-1-NK cells in the liver maintained the killing ability.CONCLUSION:Significant stress-induced apoptosis was observed among Mac-1+NK cells,but not Mac-1-NK cells in the mouse liver.Stress stimulation markedly decreased the killing activity of NK cells in the spleen but remained unchanged in the liver. | Zhen Ma Yang Liu Xin Zhou Hai-Long Yu Ming-Qi Li Chikako Tomiyama-Miyaji Toru Abo Xue-Feng Bai | 2013 | World Journal of Gastroenterology2013，19，37： | 2 |
| 19 | Lymphocytic colitis: A clue to bacterial etiology显示文摘AIM: To find out the role of bacteria as a possible etiological factor in lymphocytic colitis.METHODS: Twenty patients with histopathological diagnosis of lymphocytic colitis and 10 normal controls were included in this study. Colonoscopic biopsies were obtained from three sites (hepatic and splenic flexures and rectosigmoid region). Each biopsy was divided into two parts. A fresh part was incubated on special cultures for bacterial growth. The other part was used for the preparation of histologic tissue sections that were examined for the presence of bacteria with the help of Giemsa stain.RESULTS: Culture of tissue biopsies revealed bacterial growth in 18 out of 20 patients with lymphocytic colitis mostly Escherichia coli(14/18), which was found in all rectosigmoid specimens (14/14), but only in 8/14 and 6/14 of splenic and hepatic flexure specimens respectively. In two of these cases, E coliwas associated with proteus. Proteus was found only in one case, Klebsiella in two cases, and Staphylococcus aureus in one case. In the control group, only 2 out of 10 controls showed the growth of E coliin their biopsy cultures.Histopathology showed rod-shaped bacilli in the tissue sections of 12 out of 14 cases with positive E coliin their specimen's culture. None of the controls showed these bacteria in histopathological sections.CONCLUSION: This preliminary study reports an association between E coliand lymphocytic colitis, based on histological and culture observations. Serotyping and molecular studies are in process to assess the role of E coliin the pathogenesis of lymphocytic colitis. | Thanaa EA Helal Naglaa S Ahmed Osama Abo El Fotoh | 2005 | World Journal of Gastroenterology2005，11，46： | 2 |
| 20 | Diabetes mellitus and pancreatic tumor显示文摘 | Banzo J Velilla J Abos M D | 2004 | Rev Esp Med Nucl2004，23，1： | 1 |
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