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| 1 | Sharing Clinical Trial Data: A Proposal from the International Committee of Medical Journal Editors显示文摘The International Committee of Medical Journal Editors (ICMJE) believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves at risk.In a growing consensus,many funders around the world-foundations,government agencies,and industry-now mandate data sharing.Here,we outline ICMJE's proposed requirements to help meet this obligation.We encourage feedback on the proposed requirements.Anyone can provide feedback at www.icmje.org by April 18,2016. | Darren B Taichman Joyce Backus Christopher Baethge Howard Bauchner Peter W de Leeuw Jeffrey M Drazen John Fletcher Frank Frizelle Irish Groves Abraham Haileamlak Astrid James Christine Laine Larry Peiperl Anja Pinborg Peush Sahni Si-Nan Wu | 2016 | Chinese Medical Journal2016，，2： | 20 |
| 2 | Nature:研究鉴定出蛋白Nlrp9b抵抗轮状病毒感染机制显示文摘轮状病毒(rotavirus)是婴儿和儿童罹患肠胃炎和腹泻的一种最为常见的原因,每年导致全世界大约21.5万人死亡。它是高度传染性的和潜在致命性的。这种病毒特异性地感染宿主小肠中的肠上皮细胞,并且已进化出抵抗干扰素和NF-KB信号的策略来躲避免疫系统,这就提出一个问题:其他的宿主因子是否参与肠道粘膜中的抗病毒反应。不过,针对体内(特别是通过NLR炎性体)检测和限制肠道病毒的机制,人们知之甚少。 | Shu Zhu, Zheng Wei, Noah W. Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Liang Shan, Richard A. Flavell Siyuan Ding, Ningguo Feng, Harry B. Greenberg Siyuan Ding, Harry B. Greenberg Penghua Wang, Yujiao Zhao Wen Pan, Jun Lu Jun Zhao, Yuval Kluger Kellie A. Jurado, Clara Abraham, Erol Fikrig Erol Fikrig, Richard A. Flavell | 2017 | 现代生物医学进展2017，17，27： | 10 |
| 3 | Anastomotic biliary strictures after liver transplantation: Causes and consequences显示文摘 | Robert C. Verdonk Carlijn I. Buis Robert J. Porte Eric J. van der Jagt Abraham J. Limburg Aad P. van den Berg Maarten J.H. Slooff Paul M.J.G. Peeters Koert P. de Jong Jan H. Kleibeuker Elizabeth B. Haagsma | 2006 | Liver Transpl2006，，5： | 2 |
| 4 | Relationship between heart failure treatment and development of worsening renal function among hospitalized patients显示文摘 | Butler J Fonnan DE Abraham WT | 2004 | Am Heart J2004，147，： | 1 |
| 5 | Patients direct costs to undergo TB diagnosis显示文摘Background:A major impediment to the treatment of TB is a diagnostic process that requires multiple visits.Descriptions of patient costs associated with diagnosis use different protocols and are not comparable.Methods:We aimed to describe the direct costs incurred by adults attending TB diagnostic centres in four countries and factors associated with expenditure for diagnosis.Surveys of 2225 adults attending smear-microscopy centres in Nigeria,Nepal,Ethiopia and Yemen.Adults>18 years with cough>2 weeks were enrolled prospectively.Direct costs were quantified using structured questionnaires.Patients with costs>75^(th) quartile were considered to have high expenditure(cases)and compared with patients with costs<75^(th) quartile to identify factors associated with high expenditure.Results:The most significant expenses were due to clinic fees and transport.Most participants attended the centres with companions.High expenditure was associated with attending with company,residing in rural areas/other towns and illiteracy.Conclusions:The costs incurred by patients are substantial and share common patterns across countries.Removing user fees,transparent charging policies and reimbursing clinic expenses would reduce the poverty-inducing effects of direct diagnostic costs.In locations with limited resources,support could be prioritised for those most at risk of high expenditure;those who are illiterate,attend the service with company and rural residents. | Rachel M.Anderson de Cuevas Lovett Lawson Najla Al-Sonboli Nasher Al-Aghbari Isabel Arbide Jeevan B.Sherchand Emenyonu E.Nnamdi Abraham Aseffa Mohammed A.Yassin Saddiq T.Abdurrahman Joshua Obasanya Oladimeji Olanrewaju Daniel Datiko Sally J.Theobald Andrew Ramsay S.Bertel Squire Luis E.Cuevas | 2016 | Infectious Diseases of Poverty2016，5，1： | 1 |
| 6 | Vascular calcifications as a marker of increased cardiovascular risk: A meta-analysis显示文摘 | Roger Rennenberg Abraham Kroon Peter de Leeuw J.M.A Van Engelshoven Schurgers Alfons Kessels | 2008 | Vascular Health and Risk Management2008，，： | 1 |
| 7 | Characterization of human and mouse H19 regulatory sequences显示文摘 | Gabriel Banet Osnat Bibi Imad Matouk Suhail Ayesh Morris Laster Katherine Molner Kimber Mark Tykocinski Nathan de Groot Abraham Hochberg Patricia Ohana | 2000 | Molecular Biology Reports2000，，3： | 1 |
| 8 | 2009 focused update: ACCF/AHA guidelines for the diagnosis and manage- ment of heart failure in adults : a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation显示文摘 | JESSUP M ABRAHAM WT CASEY DE | 2009 | Cir-culation2009，119，14： | 1 |
| 9 | 2009 focused update : ACCF/ AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults 显示文摘 | Jessup M Abraham WT Casey DE | 2009 | Circulation2009，119，： | 1 |
| 10 | 2009 focused update:ACCF/AHA Guidelines for the Diagnosis and Management ofHeart Failure in Adults:a report of the American College of Cardi-ology Foundation/American Heart Association Task Force on Prac-tice Guidelines:developed in collaboration with the InternationalSociety for Heart and Lung Transplantation显示文摘 | Jessup M Abraham WT Casey DE | 2009 | Circulation2009，119，14： | 1 |
| 11 | Dermoscopy findings of alopecia areata in an African-American patient显示文摘 | de Moura LH Duque-Estrada B Abraham LS | 2008 | J Dermatol Case Rep2008，2，4： | 1 |
| 12 | Expression of heme oxygen- ase-1 in thick ascending loop of henle attenuates angiotensin Ⅱ- dependent hypertension显示文摘 | Stec DE Drummond HA Gousette MU Storm MV Abraham NG Csongradi E | 2012 | J Am Soc Nephrol2012，23，5： | 1 |
| 13 | Relationship betweenheart failure treatment and development of worsening renal functionamong hospitalized patients显示文摘 | Butler J Forman DE Abraham WT | 2004 | Am Heart J2004，147，2： | 1 |
| 14 | 2009 focused update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines 显示文摘 | Jessup M Abraham WT Casey DE | 2009 | Circulation2009，119，14： | 1 |
| 15 | Inhibitory power of kefir:the role of organic acids显示文摘 | GARROTE G L ABRAHAM A G DE ANTONI G L | 2000 | Journal of Food Protection2000，63，3： | 1 |
| 16 | ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American college of cardiology foundation task force on clinical expert consensus documents显示文摘 | Bhatt DE Scheiman J Abraham NS | 2008 | Circulation2008，118，： | 1 |
| 17 | Connective tissue growth factor : structure- function relationships of a mosaic, muhifunctional protein 显示文摘 | de WINTER P LEONI P ABRAHAM D | 2008 | Growth Factors2008，26，2： | 1 |
| 18 | Developed in collaboration with the International Society for Heart and Lung Transplantation 显示文摘 | Jessup M Abraham WT Casey DE | 2009 | Circulation2009，119，14： | 1 |
| 19 | 2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Soci- ety for Heart and Lung Transplantation 显示文摘 | Jessup M Abraham WT Casey DE | 2009 | Circulation2009，119，14： | 1 |
| 20 | ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults显示文摘 | Jessup M Abraham WT Casey DE | 2009 | Circula tion2009，119，14： | 1 |
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