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4篇 您的检索式:作者名="Abraham W.T."
    题名 作者 年代 出处 被引量
1急性失代偿性心力衰竭院内死亡率的危险分层:分类回归树分析Fonarow G.C. Adams Jr. K.F. Abraham W.T. 张迎捷 2005世界核心医学期刊文摘(心脏病学分册)2005,0,6:8
2对晚期慢性心力衰竭患者行心脏再同步化治疗致NYHA分级改善的临床预测因素和时机:多中心InSync随机临床评价(MIRACLE)和多中心InSyncICD随机临床评价(MIRACLE-ICD)试验的结果显示文摘Background: Based on current patient selection criteria, a significant proportion of recipients of cardiac resynchronization therapy(CRT) do not respond to treatment. The purpose of this analysis is to identify predictors and characterize the timing of response to CRT in patients with advanced heart failure. Methods: Patients randomized to receive CRT in the MIRACLE and MIRACLE-ICD trials, designed to assess the benefit of CRT compared with standard medical therapy in patients with advanced heart failure, left ventricular ejection fraction< 0.35, and QRS ≥130 milliseconds, were included for this analysis. Patients with an improvement of ≥1 New York Heart Association(NYHA)class from baseline to the 6-month follow-up were considered responders and those who had no change or worse NYHA class or died were classified as nonresponders. Responders were subdivided into early(within 1-3 months) and late(6 months). Results: One hundred forty-three(64%) of 224 and 190(61%) of 313 patients in the MIRACLE and MIRACLEICD trials, respectively, responded to therapy, with 81(57%) of 143 and 100(53%) of 190 responding early. Several but differing factors predicted CRT response and timing in the two trials with a high sensitivity(89%-90%) but, owing to a low specificity(31%-49%), a modest predictive accuracy(66%-75%). Conclusions: Based on improvement of ≥1 NYHA class, less than two thirds of patients enrolled in the MIRACLE or MIRACLE-ICD trials responded to CRT, with just more than half responding within the first month. Several factors predicted CRT response and timing, but given their modest predictive accuracy, comparable for both studies, additional methods for selecting candidates most likely to benefit from CRT are needed.Pires L.A. Abraham W.T. Young J.B. Johnson K.M. 刘少伟 2006世界核心医学期刊文摘(心脏病学分册)2006,2,9:0
3心力衰竭住院患者中β受体阻断剂的应用与临床结局Butler J. Young J.B. Abraham W.T. 马超 2006世界核心医学期刊文摘(心脏病学分册)2006,0,11:0
4急性心力衰竭住院患者的入院时收缩压、临床特征和预后Gheorghiade M. Abraham W.T. Albert N.M. G.C.Fonarow 马超 2007世界核心医学期刊文摘(心脏病学分册)2007,0,4:0
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