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| 1 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 2 | The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17b-estradiol and phytoestrogens in breast cancer cells显示文摘 | Maggiolini M Adele V Giovanna F | 2004 | J Biol Chem2004，279，27： | 1 |
| 3 | Short communication : Influence of microbial inoculation and co - composting material on the evolution of humic - like substances during composting of horticultural wastes 显示文摘 | Vargas - Garcia M adel Carmen Suarez - Estrella F Francisca Lopez M a Jose | 2006 | Process Biochemistry2006，41，6： | 1 |
| 4 | Extension of postharvest life of ' Mission' figs by CO2-enriched at- mospheres显示文摘 | Giancarlo C F Gordon M Adel A | 1991 | Hort Science1991，26，9： | 1 |
| 5 | Boiling peanut Arah 1 results in the formation of aggregates with reduced allergenicity显示文摘 | BLANC F VISSERS Y M ADEL P K | 2011 | Molecular Nutrition & Food Research2011，55，12： | 1 |
| 6 | Indirect Atomic Absorption and Atomic Emission Spec- trometric Determination of Antazoline, Hydralazine and Amiloride Hydrochlorides and Quinine Sulphate 显示文摘 | Yousry M Issa Hosny Ibrahim Adel F Shoukry Sabry K | 1995 | Mikro- chim Acta1995，118，： | 1 |
| 7 | Effects of alfalfa saponins on the moth Spodoptera littoralis显示文摘 | Adel M M Sehnal F Jurzysta M | 2000 | Journal of Chemical Ecology2000，26，4： | 1 |
| 8 | Mechanisms of inorganic particle formation during suspension heating of simulated aqueous wastes显示文摘 | James A M Adel F S | 1991 | Environ Sci Technol1991，25，： | 1 |
| 9 | Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors: an in vivo and in vitro study显示文摘 | Fotouhi O Adel F M Kjellman M | 2014 | Epigenetics2014，9，7： | 1 |
| 10 | Combustion aerosols:Factors governing their size and composition and implications to human health显示文摘 | Lighty JoAnn Slama Veranth John M Sarofim Adel F | 2000 | Journal of the Air and Waste Management Association2000，50，： | 1 |
| 11 | A blind source separation technique using second-order statistics 显示文摘 | Adel B Karin A M Cardoso J F | 1997 | IEEE Trans on Signal Processing1997，45，2： | 1 |
| 12 | A pilot study of long term monitoring of human move- ments in the home using accelerometry显示文摘 | MERRYN J M ADELLE C F C NIGEL H L | 2004 | Journal of Telemedicine and Telecare2004，10，3： | 1 |
| 13 | Trends in predicting and controlling ash vaporization in coal-fired utility boilers显示文摘 | ERIC G E ADEL F S CHRISTINA M L | 2001 | Fuel Processing Technology2001，71，： | 1 |
| 14 | Selection of input stimulus for fault diagnosis of analog circuits using ARMA mod- el显示文摘 | Adel Mohsen A K Abu EL-Yazeed M F | 2004 | International Journal of Electronics and Communica- tions2004，58，3： | 1 |
| 15 | A Preprocessor for Analog Circuit Fault Diagnosis Based on Prony's Method 显示文摘 | A El-Yazeed M F Adel A K Mohsen | 2003 | International Journal of Electronic and Communication(S 1434-8411)2003，57，1： | 1 |
| 16 | Azadirachtin petentiates the action of ecdysteroid agonist RH-2485 in Spodoptera littoralis显示文摘 | Adel M M Sehnal F | 2000 | J Insect Physiol2000，46，3： | 1 |
| 17 | Combustion aerosols: Factors governing their size and composition and implications to human health 显示文摘 | Joann Slama Lighty John M Veranth Adel F Sarofim | 2000 | Air and Waste Manage Assoc2000，50，： | 1 |
| 18 | A blind source separation technique using second-order statistics 显示文摘 | Adel B Karim A M Cardoso J F | 1997 | IEEE Trans on Signal Processing1997，45，2： | 1 |
| 19 | Effects o{ al{alfa saponins on the moth spodoptera littoralis显示文摘 | Adel M M Sehnal F Jurzysta M | 2000 | Journal of Chemical Ecol- ogy2000，26，10： | 1 |
| 20 | Advancing male age differentially alters levels and localization patterns of PLCzeta in sperm and testes from different mouse strains显示文摘Sperm-specific phospholipase C zeta(PLCζ)initiates intracellular calcium(Ca2+)transients which drive a series of concurrent events collectively termed oocyte activation.Numerous investigations have linked abrogation and absence/reduction of PLCζwith forms of male infertility in humans where oocyte activation fails.However,very few studies have examined potential relationships between PLCζand advancing male age,both of which are increasingly considered to be major effectors of male fertility.Initial efforts in humans may be hindered by inherent PLCζvariability within the human population,alongside a lack of sufficient controllable repeats.Herein,utilizing immunoblotting,immunofluorescence,and quantitative reverse transcription PCR(qRT-PCR)we examined for the first time PLCζprotein levels and localization patterns in sperm,and PLCζmRNA levels within testes,from mice at 8 weeks,12 weeks,24 weeks,and 36 weeks of age,from two separate strains of mice,C57BL/6(B6;inbred)and CD1(outbred).Collectively,advancing male age generally diminished levels and variability of PLCζprotein and mRNA in sperm and testes,respectively,when both strains were examined.Furthermore,advancing male age altered the predominant pattern of PLCζlocalization in mouse sperm,with younger mice exhibiting predominantly post-acrosomal,and older mice exhibiting both post-acrosomal and acrosomal populations of PLCζ.However,the specific pattern of such decline in levels of protein and mRNA was strain-specific.Collectively,our results demonstrate a negative relationship between advancing male age and PLCζlevels and localization patterns,indicating that aging male mice from different strains may serve as useful models to investigate PLCζin cases of male infertility and subfertility in humans. | Junaid Kashir Bhavesh V Mistry Maha Adel Gumssani Muhammad Rajab Reema Abu-Dawas Falah AlMohanna Michail Nomikos Celine Jones Raed Abu-Dawud Nadya Al-Yacoub Kevin Coward F Anthony Lai Abdullah M Assiri | 2021 | Asian Journal of Andrology2021，23，2： | 0 |
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