|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Polymorphism in the interleukin-17A promoter contributes to gastric cancer显示文摘AIM:To evaluate the contribution of the G-197A polymorphism in the interleukin-17(IL-17)promoter region to gastric cancer risk in an Iranian population.METHODS:We performed a case control study using samples from 161 individuals with gastric cancer and171 healthy controls.For each individual,the G-197A genotype was determined by restriction fragment length polymorphism analysis of polymerase chain reaction-amplified fragments.Statistical analyses were performed to determine whether any demographic or behavioral factors,infection with Helicobacter pylori(H.pylori),or a particular G-197A genotype was associated with gastric cancer risk.RESULTS:We found that the G-197A genotype wassignificantly associated with increased gastric cancer risk(P=0.001).Patients who were homozygous(AA)at position-197 were 2.9 times more likely to develop disease(95%CI:1.56-5.4;P=0.001).Furthermore,logistic regression analysis revealed that the presence of a single A allele increased the risk of gastric cancer up to 1.7-fold(95%CI:1.26-2.369;P=0.001).This association was observed for early stage gastric adenocarcinomas only,and was not linked to H.pylori infection.CONCLUSION:These results suggest that carrying one or more G-197A polymorphisms at position-197 in the IL-17 promoter region significantly increases gastric cancer risk in this patient population. | Alireza Rafiei Vahid Hosseini Ghasem Janbabai Abuzar Ghorbani Abulghasem Ajami Touraj Farzmandfar Maedeh Darzyani Azizi Jeremy J Gilbreath D Scott Merrell | 2013 | World Journal of Gastroenterology2013，19，34： | 7 |
| 2 | A multi-objective gravitational search algorithm based approach of power system stability enhancement with UPFC显示文摘On the basis of the theoretical analysis of a single-machine infinite-bus (SMIB),using the modified linearized Phillips-Heffron model installed with unified power flow controller (UPFC),the potential of the UPFC supplementary controller to enhance the dynamic stability of a power system is evaluated by measuring the electromechanical controllability through singular value decomposition (SVD) analysis.This controller is tuned to simultaneously shift the undamped electromechanical modes to a prescribed zone in the s-plane.The problem of robust UPFC based damping controller is formulated as an optimization problem according to the eigenvalue-based multi-objective function comprising the damping factor,and the damping ratio of the undamped electromechanical modes to be solved using gravitational search algorithm (GSA) that has a strong ability to find the most optimistic results.The different loading conditions are simulated on a SMIB system and the rotor speed deviation,internal voltage deviation,DC voltage deviation and electrical power deviation responses are studied with the effect of this flexible AC transmission systems (FACTS) controller.The results reveal that the tuned GSA based UPFC controller using the proposed multi-objective function has an excellent capability in damping power system with low frequency oscillations and greatly enhances the dynamic stability of the power systems. | Ajami Ali Armaghan Mehdi | 2013 | Journal of Central South University2013，20，6： | 6 |
| 3 | Independent component analysis approach for fault diagnosis of condenser system in thermal power plant显示文摘A statistical signal processing technique was proposed and verified as independent component analysis(ICA) for fault detection and diagnosis of industrial systems without exact and detailed model.Actually,the aim is to utilize system as a black box.The system studied is condenser system of one of MAPNA's power plants.At first,principal component analysis(PCA) approach was applied to reduce the dimensionality of the real acquired data set and to identify the essential and useful ones.Then,the fault sources were diagnosed by ICA technique.The results show that ICA approach is valid and effective for faults detection and diagnosis even in noisy states,and it can distinguish main factors of abnormality among many diverse parts of a power plant's condenser system.This selectivity problem is left unsolved in many plants,because the main factors often become unnoticed by fault expansion through other parts of the plants. | Ajami Ali Daneshvar Mahdi | 2014 | Journal of Central South University2014，21，1： | 6 |
| 4 | Functionally graded additive manufacturing to achieve functionality specifications of osteochondral scaffolds显示文摘 | Mario Monzon Chaozong Liu Sara Ajami Miguel Oliveira Ricardo Donate Viviana Ribeiro Rui L. Reis | 2018 | Bio-Design and Manufacturing2018，1，1： | 6 |
| 5 | Inducible nitric oxide synthetase genotype and Helicobacter pylori infection affect gastric cancer risk显示文摘AIM:To investigate the association of the inducible nitric oxide synthetase(iNOS) C150T polymorphism with Helicobacter pylori(H.pylori) infection and gastric cancer(GC) risk in Iran.METHODS:In order to determine whether there was a correlation between iNOS genotype and GC in Iran,we conducted a case-control study using samples from 329 individuals.For each sample,the C150T iNOS polymorphism was genotyped by polymerase chain reaction(PCR) and restriction digestion.Patients were grouped by cancer presence,demographic and behavior characteristics,and H.pylori infection status.Statistical tests were conducted to determine whether any behavioral factors or a particular iNOS genotype was associated with GC in the study population.RESULTS:In this population,we found that smoking,hot beverage consumption,a familial history of GC and H.pylori infection status were significantly associated with GC development(P = 0.015,P < 0.001,P = 0.0034,and P < 0.015,respectively).The distribution of the C150T iNOS genotypes among the two study groups was not statistically significant alone,but was impacted by H.pylori infection status.When compared to the non-H.pylori infected group,cancer patients who had a heterozygous CT genotype and were also infected with H.pylori were 2.1 times more at risk of developing GC [odds ratio(OR) = 2.1,P = 0.03] while those with a homozygous TT genotype and infected with H.pylori were 5.0 times more at risk of developing GC(OR = 5.0,P = 0.029).In contrast,this association was not seen in patients in the control group.CONCLUSION:A CT or TT polymorphism at position 150 in the iNOS gene significantly increases the risk of GC and may be a marker for GC susceptibility. | Alireza Rafiei Vahid Hosseini Ghasem Janbabai Bahman Fazli Abulghasem Ajami Zahra Hosseini-khah Jeremy J Gilbreath D Scott Merrell | 2012 | World Journal of Gastroenterology2012，18，35： | 4 |
| 6 | Effect of Gd3+-,Pr3+-or Sm3+-substituted cobalt-zinc ferrite on photodegradation of methyl orange and cytotoxicity tests显示文摘Gd3+-,Pr3+-or Sm3+-doped Co-Zn(Co0.5Zn0.5Fe2 O4)magnetic ferrites(i.e.,Co0.5Zn0.5Gd0.1Fe1.9O4,Co0.5Zn0.5Pr0.1Fe1.9O4 and Co0.5Zn0.5Sm0.1Fe1.9O4)were prepared using a facile sol-gel approach,and the structure,surface morphology and chemical composition of the products were studied by means of scanning electron microscopy(SEM),energy dispersive X-ray analysis(EDX),X-ray diffraction(XRD),UVvisible diffuse reflectance spectroscopy(DRS),photoluminescence(PL)spectroscopy,Fourier transform infrared spectroscopy(FT-IR)and vibrating sample magnetometer(VSM)spectroscopy.XRD patterns show the Co-Zn product is composed of cubic spinel phases with few impurities or secondary phases,and the average crystallite sizes of the samples are determined to be approximately^51—80,~99—181,~68—103 and^83—133 nm.Also the coercivity and remnant and saturation magnetizations,evaluated by vibrating sample magnetometer(VSM),are found to increase linearly with the incorporation of Gd3+,Pr3+and Sm3+in the product formulation.The CO1-xZnxFe2-yRyO4 photocatalyst sample is found to display a red shift in its absorption,and exhibits outstanding photocatalytic effects in the degradation of MO under ultraviolet(UV)light.This is attributed to the reduction of the band gap of cobalt-zinc ferrite due to the presence of rare earth ions.Further in vitro evaluations of the cytotoxic effects of the synthesized nanoparticles were performed on a HeLa cell line. | Seyed Mahdi Peymani-Motlagh Nadia Moeinian Mojtaba Rostami Mahdi Fasihi-Ramandi Ali Sobhani-Nasab Mehdi Rahimi-Nasrabadi Mohammad Eghbali-Arani Mohammad Reza Ganjali Teofil Jesionowski Hermann Ehrlich Mohammad Ali Karimi Narges Ajami | 2019 | Journal of Rare Earths2019，37，12： | 3 |
| 7 | Polycaprolactone-carboxymethyl cellulose composites for manufacturing porous scaffolds by material extrusion显示文摘Polycaprolactone-carboxymethyl cellulose composites have been obtained and used to print porous structures by material extrusion.The materials used contained 0,2 and 5% w/w of the carboxymethyl cellulose additive.These structures have been analyzed in terms of their morphology (including the evaluation of their porosity),mechanical properties under compression load and cell affinity.Cell affinity has been evaluated by culturing sheep mesenchymal stem cells and analyzing their viability by the Alamar Blue(R)assay at days 1,3,6 and 8.The results show that composites samples have similar values of porosity and apparent density than pure polycaprolactone ones.However,samples containing 5%w/w of carboxymethyl cellulose have micropores on the filaments due to a hindered deposition process.This characteristic affects the mechanical properties of the structures,so these ones have a mean compression modulus significantly lower than pure polycaprolactone scaffolds.However, the samples containing 2%w/w of carboxymethyl cellulose show no significant difference with the pure polycaprolactone ones in terms of their mechanical properties.Moreover,the presence of 2%w/w of additive improves cell proliferation on the surface of the porous structures.As complementary information,the flow properties of the composite materials were studied and the power law equations at 210℃ obtained,as this temperature was the 3D printing temperature.These equations can be useful for simulation and designing purposes of other manufacturing processes. | M.E.Aleman-Domfnguez Z.Ortega A.N.Benitez Mario Monzon L.V.Garzon Sara Ajami Chaozong Liu | 2018 | Bio-Design and Manufacturing2018，1，4： | 2 |
| 8 | The leading cause of gastroen- teritis worldwide 显示文摘 | Koo HL Ajami N Atmar RL | 2010 | Discovery Medicine2010，10，： | 1 |
| 9 | Evaluation of myocardial function using the Tei index in patients with Kawasaki disease显示文摘 | Ajami G Borzouee M Amoozgar H | 2010 | Cardiol Young2010，20，1： | 1 |
| 10 | Fecal microbiota imbalance in Mexican children with type 1 diabetes显示文摘 | Mejia-Leon ME Petrosino JF Ajami NJ | 2014 | Sci Rep2014，4，： | 1 |
| 11 | LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models显示文摘 | S. Betty Yan Victoria L. Peek Rose Ajamie Sean G. Buchanan Jeremy R. Graff Steven A. Heidler Yu-Hua Hui Karen L. Huss Bruce W. Konicek Jason R. Manro Chuan Shih Julie A. Stewart Trent R. Stewart Stephanie L. Stout Mark T. Uhlik Suzane L. Um Yong Wang Wenj | 2013 | Investigational New Drugs2013，，4： | 1 |
| 12 | Evaluation of myocardial function using the Tei index in patients with Kawasaki disease 显示文摘 | Ajami G Borzouee M Amoozgar H et at | 2010 | Cardiol Young2010，20，1： | 1 |
| 13 | Multi-model ensemble hydrologic prediction using Bayesian model averaging显示文摘 | Duan Q Ajami N K Gao X Sorooshian S | 2007 | Advances in Water Resources2007，30，： | 1 |
| 14 | Evaluation of myocardial function by pulsed tissue Doppler in Kawasaki disease显示文摘 | Amoozgar H Mehdizadeh S Ajami G | 2009 | Pediatr Cardiol2009，30，7： | 1 |
| 15 | Comparison of mic- roleakage of three adhesive systems in class V composite restora- tions prepared with Er, Cr: YSGG laser 显示文摘 | Kimyai S Ajami AA Chaharom ME | 2010 | Photomed Laser Surg2010，28，4： | 1 |
| 16 | Design, Analysis and Implementation of a Buck-Boost DC-DC Converter显示文摘 | Ajami Farakhor Amir | 2014 | IET Power Electronics2014，7，12： | 1 |
| 17 | Glutamine:The emperor or his clothes显示文摘 | Young V Ajami A | 2001 | The Journal of Nutrition(9S)2001，131，： | 1 |
| 18 | Glutamatez an animo acid of particular distinction显示文摘 | Young V R Ajami A M | 2000 | J Nutr2000，130，： | 1 |
| 19 | Multi-model ensemble hydrologic prediction using Bayesian model averaging显示文摘 | DUAN Q AJAMI N K GAO Xiao-gang | 2007 | Advances in Water Resources2007，30，5： | 1 |
| 20 | Semi-mechanistic pharmacokinetic/pharmacodynamic modeling of the antitumor activity of LY2835219, anew cyclin-dependent kinase 4/6 inhibitor, in mice bearing human tumorxenografts显示文摘 | Tate S C Cai S Ajamie R T | 2014 | Clin Cancer Res2014，20，14： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员