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| 1 | Chloroplast phylogenomics of the New World grape species (Vitis, Vitaceae)显示文摘Vitis L。(葡萄类) 是经济地很重要的水果庄稼,葡萄和酒的来源。在类以内的种系发生的关系是高度争论的。此处,我们从整个 plastomes 采用顺序数据试图提高 Vitis 种系发生的分辨率。结果作为 monophyletic 支持新世界 Vitis 亚属 Vitis。在 clade 以内, V。californica 是到仍然保持新的姐妹世界 Vitis 亚属 Vitis。在亚属 Vitis 以内,而且,欧亚的 clade 要用体力地被支持并且是到新世界 clade 的姐妹。Vitis vinifera ssp 的 clade。vinifera 和 V。vinifera ssp。sylvestris 是到 Vitis 的核心亚洲人 clade 的姐妹。在北美洲的几普遍的种被发现例如,是在 plastome 树上的 nonmonophyletic 广泛地定义的 Vitis cinerea 和 V。aestivalis 各个需要被分成几种。可能也 nonmonophyly 某种类由于在北美的 Vitis 的杂交的普通出现。由进九个系列的 Munson 的北美的 Vitis 的分类基于种系发生的结果被讨论。分叉时间和系多样化的分析在在晚第三纪开始的北美洲支持 Vitis 的快速的放射。 | Jun Went AJ Harris Yash Kalburgi Ning Zhang Yuan Xu Wei Zheng Stefanie M. Ickert-Bondt Gabriel Johnson Elizabeth A. Zimmer | 2018 | Journal of Systematics and Evolution2018，56，4： | 14 |
| 2 | A molecular phylogeny of Staphyleaceae: Implications for generic delimitation and classical biogeographic disjunctions in the family显示文摘Staphyleaceae 传统地包括适度、热带的树和灌木的三个类:Euscaphis Siebold 与 Zucc, Staphylea L. ,和 Tuprinia 发泄。这些类被形态学,而是一个最近的分类清楚地基于四叶绿体基因支持并且原子它的享受 Staphylea, Euscaphis,和在 Staphylea s.l 的新世界 Turpinia 和在 Dalrympelea Roxb 的旧世界 Turpinia。在这研究,我们的目的到过(1 ) 在使用二的 Staphyleaceae 以内解决种系发生的关系原子并且六个叶绿体标记,(2 ) 探索词法 synapomorphies 支持主要 clades,并且(3 ) 在通用定界线和生物地理学上讨论我们的结果的含意。我们的种系发生的结果在 Staphyleaceae 显示出五主要 clades:(1 ) 旧世界 Turpinia,(2 ) 新世界 Turpinia,(3 ) 只旧的世界 Staphylea 的 clade,(4 ) 包括所有新世界种类和旧世界的其余部分的 Staphylea 的亚洲北方的美国 clade,并且(5 ) Euscaphis。在 Staphylea 和 Turpinia 的二 clades 各个以内,传统地使用限定类的词法特征可以展出集中。在在这研究检验的词法特征之中,我们发现那花粉不是分类地增进知识的,叶牙齿展示, epicuticular 给表演打蜡分别地,为 Staphylea 和 Tuprinia 的传统的类限制了支持并且花瓣长度(即,花尺寸)在与新世界 Turpinia 相比的旧世界 Turpinia 是显著地更小的。关于生物地理学,我们的结果支持在东方北美洲和喜马拉雅山脉之间的稀罕分离。 | AJ Harris Ping-Ting Chen Xin-Wei Xu Jian-Qiang Zhang Xue Yang Jun Wen | 2017 | Journal of Systematics and Evolution2017，55，2： | 4 |
| 3 | Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection显示文摘The p38 mitogen-activated protein kinase(MAPK)plays an evolutionarily conserved role in the cellular re-sponse to microbial infection and environmental stress.Activation of p38 is mediated through phosphorylation by upstream MAPKK,which in turn is activated by MAPKKK.In the Caenorhabditis elegans,the p38 MAPK(also called PMK-1)signaling pathway has been shown to be required in its resistance to bacterial infection.However,how different upstream MAP2Ks and MAP3Ks specifically contribute to the activation of PMK-1 in response to bacterial infection still is not clearly un-derstood.By using double-stranded RNA-mediated interference(RNAi)and genetic mutants of C.elegans,we demonstrate that C.elegans MOM-4,a mammalian TAK1 homolog,is required for the resistance of C.elegans to a P.aeruginosa infection.We have also found that the MKK-4 of C.elegans is required for P.aeruginosa resistance,but not through the regulation of DLK-1.In summary,our results indicate that different upstream MAPKKKs or MAPKKs regulate the activation of PMK-1 in response to P.aeruginosa. | Ajing Xu Guojun Shi Feng Liu Baoxue Ge | 2013 | Protein & Cell2013，4，1： | 3 |
| 4 | Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation 显示文摘 | Xu J Haigis KM Firestone AJ | 2013 | Cancer Discov2013，3，9： | 1 |
| 5 | Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the diabetes heart study显示文摘 | Cox AJ Ng MC Xu J | | Atherosclerosis0，，1： | 1 |
| 6 | Pediatric brain injury: can DTI scalars predict functional outcome? 显示文摘 | Xu D Mukherjee P Barkovich AJ | 2013 | Pediatr Radiol2013，43，1： | 1 |
| 7 | Pharmacokinetics of caffeine in plasma and saliva, and the influence of caffeine abstinence on CYP1A2 metrics显示文摘 | Perera V Gross AS Xu H McLachlan AJ | 2011 | J Pharm Pharmacol2011，63，9： | 1 |
| 8 | Hybrid deep learning model for risk prediction of fracture in patients with diabetes and osteoporosis显示文摘The fracture risk of patients with diabetes is higher than those of patients without diabetes due to hyperglycemia,usage of diabetes drugs,changes in insulin levels,and excretion,and this risk begins as early as adolescence.Many factors including demographic data(such as age,height,weight,and gender),medical history(such as smoking,drinking,and menopause),and examination(such as bone mineral density,blood routine,and urine routine)may be related to bone metabolism in patients with diabetes.However,most of the existing methods are qualitative assessments and do not consider the interactions of the physiological factors of humans.In addition,the fracture risk of patients with diabetes and osteoporosis has not been further studied previously.In this paper,a hybrid model combining XGBoost with deep neural network is used to predict the fracture risk of patients with diabetes and osteoporosis,and investigate the effect of patients’physiological factors on fracture risk.A total of 147 raw input features are considered in our model.The presented model is compared with several benchmarks based on various metrics to prove its effectiveness.Moreover,the top 18 influencing factors of fracture risks of patients with diabetes are determined. | Yaxin Chen Tianyi Yang Xiaofeng Gao Ajing Xu | 2022 | Frontiers of Medicine2022，16，3： | 1 |
| 9 | Odorant-binding proteins of the ma- laria mosquito Anopheles funestus sensu stricto 显示文摘 | Xu W Cornel AJ Leal WS | 2010 | PLoS One2010，5，15： | 1 |
| 10 | Lactate clearance time and concentration linked to morbidity and death in cardiac surgical patients显示文摘 | Lindsay AJ Xu M Sessler DI Blackstone EH | 2013 | Ann Thorac Surg2013，95，2： | 1 |
| 11 | Identification and characterization of microRNAs in Clonorchis sinensis of human health significance 显示文摘 | Xu MJ Liu Q Nisbet AJ | 2010 | BMC Genomics2010，11，： | 1 |
| 12 | Ascaris suum:RNAi medi- ated silencing of enolase gene expression in infective larvae显示文摘 | Chen N Xu MJ Nisbet AJ | 2011 | Exp Parasitol2011，127，1： | 1 |
| 13 | Glial reactivety and impaired glutame metabolism in short-term experimental diabetic retinopathy显示文摘 | Leith E Barber AJ Xu B | | 0，，07： | 1 |
| 14 | CD8 T cells mediate transient herpes stromal keratitis in CD4-deficient mice显示文摘 | Lepisto AJ Frank GM Xu M | | 0，，： | 1 |
| 15 | Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases 显示文摘 | Zhou Z Cironi P Lin AJ Xu YQ Hrvatin S Golan DE Silver PA Walsh CT Yin J | 2007 | Acs Chem Biol2007，2，5： | 1 |
| 16 | Expression of Ku86 and presence of Ku86 antibody as biomarkers of hepatitis B virus related hepatocellular carcinoma 显示文摘 | Xu Y Liu AJ Gao YX | 2014 | Dig Dis Sci2014，59，3： | 1 |
| 17 | Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy显示文摘 | Lieth E Barber AJ Xu B | 1998 | Diabetes1998，47，： | 1 |
| 18 | Generation of a germ cell nuclear factor conditional allele in mice显示文摘 | Lan Z J Xu X Cooney AJ | | 0，，04： | 1 |
| 19 | Pediatric brain injury: can DTI scalars predict functional outcome? 显示文摘 | Xu D Mukherjee P Barkovich AJ | 2013 | Pediatr Radiol2013，43，1： | 1 |
| 20 | Opsonization with Clq and mannose-binding lectin targets apoptotic cells todendritie cells显示文摘 | Nauta AJ Castellano G Xu W | 2004 | J Immunol2004，173，： | 1 |
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