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| 1 | Hemoglobin A1c in early postpartum screening of women with gestational diabetes显示文摘AIM:To assess the utility of hemoglobin A1c(HbA1c) in the early postpartum screening of women with gestational diabetes mellitus(GDM).METHODS:Over a 3 years period,HbA1c estimations were undertaken in addition to and simultaneously with the traditional oral glucose tolerance test(OGTT),in 203 women with GDM as a part of early postpartum screening for dysglycaemia,at 6 wk post-partum.World Health Organization criteria was used for diagnosing diabetes:fasting blood glucose(FBG) ≥ 7.0 mmol/Land/or 2-h postprandial blood glucose(PPBG) ≥ 11.1 mmol/L and/or HbA1c ≥ 48 mmol/mol;and impaired glycaemiastate:impaired fasting glucose 6.1-6.9 mmol/L and/or impaired glucose tolerance 7.8-11.0 mmol/L and/or HbA1c:42-47 mmol/mol.RESULTS:Mean FBG,2-h PPBG and HbA1c were 4.9 ± 0.7 mmol/L,5.6 ± 2.0 mmol/L and 38 ± 5 mmol/mol respectively.FBG,2-h PPBG and HbA1c detected 6(3%),7(3.5%) and 11(5.4%) cases of diabetes respectively,and 11(5.4%),25(12.3%) and 23(11.3%) cases of pre-diabetes state respectively.HbA1c values ≥ 48 mmol/mol(≥ 6.5%) showed a diagnostic sensitivity of 71.4% and specificity of 98.5% for diabetes in comparison to OGTT in receiver operating characteristics curve analysis.At HbA1c cut-off 44 mmol/mol,sensitivity and specificity were 100% and 92.3% respectively [area under the curve:0.98(95%CI:0.96-1.00)].Sensitivity and specificity for detecting high risk 'impaired glycaemia' state [HbA1c 42 mmol/mol(6.0%)] were 28% and 80%,respectively.CONCLUSION:HbA1c level ≥ 48 mmol/mol(≥ 6.5%) has reasonable sensitivity and high specificity in comparison to OGTT for early postpartum screening of diabetes in GDM.At 6 th week postpartum screening,if FBG is normal and HbA1c < 44 mmol/mol OGTT is not recommended. | Mahesh V Katreddy Joseph M Pappachan Sarah E Taylor Radha Indusekhar Ananth U Nayak Alan M Nevill | 2013 | World Journal of Diabetes2013，4，3： | 2 |
| 2 | Large cystic lesions of the liver in adults: a 15-year experience in a tertiary center 1 1 No competing interests declared.显示文摘 | Arie Regev K.Rajender Reddy Mariana Berho Dan Sleeman Joe U Levi Alan S Livingstone David Levi Unzila Ali Enrique G Molina Eugene R Schiff | 2001 | Journal of the American College of Surgeons2001，，1： | 2 |
| 3 | Emerging roles of caspase-3 in apoptosis显示文摘 | Alan G Porter Reiner U | 2006 | Cell Death Different2006，6，2： | 1 |
| 4 | Broad patterns of gene expression revealed by clustering analysis of tumor and no malcolon tissues probed by microarrays显示文摘 | Alan U BarkaiN Notterman D | 1999 | Cell Biology1999，96，： | 1 |
| 5 | Haematological manifestations in patients with severe acute respiratory syndrome:retrospective analysis显示文摘 | ALAN W U TO K F | 2003 | BJM2003，326，7403： | 1 |
| 6 | Horseshoe lung asscociated with left-lung hypoplasia,left pulmonary artery sling and bilateral agenesis of upper lobe bronchi显示文摘 | Oguz B Alan S Ozcelik U | 2009 | Pediatr Radio12009，39，9： | 1 |
| 7 | Volatile substance of Chinese traditional Jinhua ham and cantonese sausage显示文摘 | DU M ALAN D U | 2001 | Food Chemistry and Toxicology2001，66，： | 1 |
| 8 | Early detec- tion of C-reactive protein and yon Willebrand factor levels in Malaysian patients with acute coronary syndrome 显示文摘 | Wen N T Edmund U H S Alan Y Y F | 2013 | J Car- diovasc Dis Res2013，4，1： | 1 |
| 9 | Bio-absorbable soy protein plastic composites:Effect of polyphosphate fillers on biodegradability显示文摘 | ALAN H T JOSHUA U O KAI-LAI G H | 2001 | Journal of Polymers and the Environment2001，，1： | 1 |
| 10 | Enzyme-containing mi- chael -- Adduet-based coatings 显示文摘 | G6raldine F D Claus U Alan J R | 2003 | Biomacromolecules2003，4，： | 1 |
| 11 | Volatile substance of Chinese tranditional Jinhuahamand Cantonese sausage显示文摘 | DU M ALAN D U | 2001 | Food Chemistry and Toxicology2001，66，6： | 1 |
| 12 | ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis显示文摘 | CHEN J G HEMAYET U JEFFERY C Y MICHAEL R S ALAN M J | 2001 | Genes &Development2001，15，： | 1 |
| 13 | Emerging roles of Caspase-3in apoptosis显示文摘 | Alan G Porter Reiner U Ja(E) nicke | 1999 | Cell Death and Differentiation1999，6，： | 1 |
| 14 | Detection of wide spread fluids in the Tibetan crust by magnetotelluric studies显示文摘 | Wei Wenbo Martyn U Alan J | 2001 | Science2001，292，27： | 1 |
| 15 | Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase10显示文摘 | ALAN G P REINER U J | 1999 | J Biol Chem1999，274，10： | 1 |
| 16 | Liver stiffness measurement in combination with noninvasive markers for the improved diagnosis of B-viral liver cirrhosis 显示文摘 | Kim S U Alan S H Park J Y | 2009 | Clin Gastroenterol2009，43，3： | 1 |
| 17 | Serum uric acid is a determi- nant of metabolic syndrome in a population -based study显示文摘 | Alan O Huseyln U Gulay H | 2006 | Am J Hyportenses2006，19，10： | 1 |
| 18 | Volatile substance of Chinese traditional Jinhuaham and cantonese sausage显示文摘 | ALAN D U DU M | 2001 | Journal of Food Science2001，66，6： | 1 |
| 19 | Pneumatic lithotripter application for giant bladder stone in a patient with augmentation cystoplasty显示文摘 | YALCIN V ALAN C ONDER A U | 2004 | J Endourol2004，18，5： | 1 |
| 20 | Emerging Roles of Caspase-3 in Apoptosis 显示文摘 | JANICKE RRINER U PORTER ALAN G | 1999 | Cell Death and Differentiation1999，6，2： | 1 |
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