|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Magnetic resonance elastography is accurate in detecting advanced fibrosis in autoimmune hepatitis显示文摘To assess the value of magnetic resonance elastography(MRE) in detecting advanced fibrosis/cirrhosis in autoimmune hepatitis(AIH).METHODS In this retrospective study, 36 patients(19 treated and 17 untreated) with histologically confirmed AIH and liver biopsy performed within 3 mo of MRE were identified at a tertiary care referral center. Liver stiffness(LS) with MRE was calculated by a radiologist, and inflammation grade and fibrosis stage in liver biopsy was assessed by a pathologist in a blinded fashion. Two radiologistsevaluated morphological features of cirrhosis on conventional magnetic resonance imaging(MRI). Accuracy of MRE was compared to laboratory markers and MRI for detection of advanced fibrosis/cirrhosis.RESULTS Liver fibrosis stages of 0, 1, 2, 3 and 4 were present in 4, 6, 7, 6 and 13 patients respectively. There were no significant differences in distribution of fibrosis stage and inflammation grade between treated and untreated patient groups. LS with MRE demonstrated stronger correlation with liver fibrosis stage in comparison to laboratory markers for chronic liver disease(r = 0.88 vs-0.48-0.70). A trend of decreased mean LS in treated patients compared to untreated patients was observed(3.7 k Pa vs 3.84 k Pa) but was not statistically significant. MRE had an accuracy/sensitivity/specificity/positive predictive value/negative predictive value of 0.97/90%/100%/100%/90% and 0.98/92.3%/96%/92.3%/96% for detection of advanced fibrosis and cirrhosis, respectively. The performance of MRE was significantly better than laboratory tests for detection of advanced fibrosis(0.97 vs 0.53-0.80, P < 0.01), and cirrhosis(0.98 vs 0.58-0.80, P < 0.01) and better than conventional MRI for diagnosis of cirrhosis(0.98 vs 0.78, P = 0.002).CONCLUSION MRE is a promising modality for detection of advanced fibrosis and cirrhosis in patients with AIH with superior diagnostic accuracy compared to laboratory assessment and MRI. | Jin Wang Neera Malik Meng Yin Thomas C Smyrk Albert J Czaja Richard L Ehman Sudhakar K Venkatesh | 2017 | World Journal of Gastroenterology2017，23，5： | 15 |
| 2 | Diabetes mellitus, revascularization and outcomes in elderly patients with myocardial infarction-related cardiogenic shock显示文摘Background The prognostic role of diabetes mellitus(DM)in elderly patients with myocardial infarction-related cardiogenic shock(MI-CS)remains controversial.Little information exists about the impact of intensive cardiac care unit(ICCU)and revascularization on outcomes of elderly patients with MI-CS.We aimed to assess the prognostic impact of DM according to age in patients with MI-CS,and to analyze the impact ICCU management and revascularization on in-hospital mortality in MI-CS patients at older ages.Methods Discharge episodes with diagnosis of CS associated with MI were selected from the Spanish National Health System’s Basic Data Set.Centers were classified according to their availability of ICCU.Main outcome measured was in-hospital mortality.Results A total of 23,590 episodes of MI-CS were identified,of whom 12,447(52.8%)were in patients aged≥75 years.The impact of DM on in-hospital mortality was different among age subgroups.While in younger patients,DM was associated to a higher mortality risk(0.52 vs.0.47,OR=1.12,95%CI:1.06–1.18,χ^2<0.001),this association became non-significant in older patients(0.76 vs.0.81,χ^2=0.09).Adjusted mortality rate of MI-CS aged≥75 years was lower in patients admitted to hospitals with ICCU(adjusted mortality rate:74.2%vs.77.7%,P<0.001)and in patients undergoing revascularization(74.9%vs.77.3%,P<0.001).Conclusions Prognostic impact of DM in patients with MI-CS was different according to age,with a significantly lower impact at older ages.The availability of ICCU and revascularization were associated with better outcomes in these complex patients. | Miquel Gual Albert Ariza-Solé María García Márquez Cristina Fernández JoséL Bernal Francesc Formiga María-Isabel Barrionuevo JoséC Sánchez-Salado Victòria Lorente Júlia Pascual Isaac Llaó Oriol Alegre Angel Cequier Javier Elola | 2020 | Journal of Geriatric Cardiology2020，17，10： | 2 |
| 3 | Integrin alpha v beta 3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models显示文摘 | Albert JM Cao C Geng L | 2006 | Int J Radiat Oncol Biol Phys2006，65，5： | 1 |
| 4 | Beneficial effects of estrogen treatment in the HLA-B27 transgenic rat model of inflammatory bowel disease显示文摘 | Harnish D C Albert L M Leat hurby Y | | 0，，01： | 1 |
| 5 | Information systems project management: an agency theory interpretation显示文摘 | Mahaney C Robert Lederer L Albert | 2003 | The Journal of Systems and Software2003，68，： | 1 |
| 6 | Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘 | Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R | 2009 | Journal of Bacteriology2009，191，16： | 1 |
| 7 | Real-time detection of gastric insufflation related to facemask pressure-controlled ventilation using ultrasonography of the antrum and epigastric auscultation in nonparalyzed patients:aprospective,randomized,double-blind study显示文摘 | Bouvet L Albert ML Augris C | 2014 | Anesth2014，120，2： | 1 |
| 8 | Randomized phase fl study ofcarboplatin and etoposide with or without obatoclax mesylate inextensive-stage small cell lung cancer显示文摘 | Langer C Albert L Kovacs P | 2014 | Lung Cancer2014，85，42： | 1 |
| 9 | Shape-specific recognition in the structure of the Vtslp SAM domain with RNA显示文摘 | Florian C Albert L Richard S | 2006 | Nature Structural Molecular Biology2006，13，2： | 1 |
| 10 | Oxaliplatin, fluorouracil, and leueovorin for patients with unresectable liveronly metastases from eoloreetal cancer: A North Central Cancer Treatment Gro-up Phase II study显示文摘 | Alberts SR Horvath W L StemFeld W C | 2005 | J Clin Oncoi2005，23，36： | 1 |
| 11 | Mechanical properties of Nylon bonded Nd-Fe-B permanent magnets显示文摘 | Monika G G Albert J S Ma B M Edgar L C Ronald O S | 2003 | Journal of Magnetism and Magnetic Materials2003，257，： | 1 |
| 12 | Periodic Motions and Grazing in a Harmonically Forced, Piecewise, Linear Oscillator with Impacts显示文摘 | Albert C J L Chen Lidi | 2005 | Chaos Soiltons & Fractals2005，24，2： | 1 |
| 13 | 显示文摘 | Albert K J Lewis N S Schauer C L | 2000 | Chem Rev2000，100，： | 1 |
| 14 | Factors af- fecting the success of a construction project显示文摘 | ALBERT P C C DAVID S ADA P L C | 2004 | Jour- nal of Construction Engineering and Management2004，130，1： | 1 |
| 15 | Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase Ⅱ study显示文摘 | Alberts S R Horvath W L Sternfeld W C | 2005 | J Clin Oncol2005，23，36： | 1 |
| 16 | Developing a PC-based automated monitoring and control platform for electric power systems显示文摘 | Albert W L C H Ku | 2003 | Electric Power Systems Research2003，64，2： | 1 |
| 17 | The draft genome of the transgenic tropical fruit tree papaya ( Carica pap aya Linnaeus ) 显示文摘 | MING R HOU S B FENG Y YU Q DIONNE-LAPORTE A SAW J H SENIN P WANG W LY B V LEWIS K L T SALZBERG S L FENG L GONES M R SKELTON R L MURRAYJ E CHEN C QIAN W SHEN J DU P EUSTICE M TONG E TANG H LYONS E PAULL R E MICHAEL T P WALL K RICE D W ALBERT H WANG M L ZHU Y J SCHATZ M NAGARAJAN N ACOB R A GUAN P BLAS A WAI C M ACKERMAN C M REN Y LIU C WANG J M WANG J P NA J SHAKIROV E V HAAS B THIMMAPURAM J NELSON D WANG X BOWERS J E GSCHWEND A R DELCHER A L SINGH R SUZUKI J Y TRIPATHI S NEUPANE K WEI H IRIKURA B PAIDI M JIANG N ZHANG W PRESTING G WINDSOR A NAVAJAS-PEREZ R TORRES M J FELTUS A PORTER B LI Y BURROUGHS A M LUO M C LIU L CHRISTOPHER D A MOUNT S M MOORE P H SUGIMURA T JIANG J SCHULER M A FRIEDMAN V MITCHELL-OLDS T SHIPPEN D E PAMPHILIS C W PALMER J D FREELING M PATERSON A H GONSALVES D WANG L ALAM M | 2008 | Nature2008，452，： | 1 |
| 18 | Effects of boron on the physiological activity of Zinc in maize 显示文摘 | BOHNSACK C W ALBERT L S | 1977 | Plant Physiol1977，59，： | 1 |
| 19 | Simplified technique for laparoscopic extravesical ureteral reimplantation in the porcine model显示文摘 | Baldwin D D Pope J C Alberts G L | 2005 | J Endourol2005，19，： | 1 |
| 20 | Intensive care adult patients with severe respiratory failure caused by influenza A(H1N1)v in Spain显示文摘 | Rello J Rodríguez A Ibaez P Socias L Cebrian J Marques A Guerrero J Ruiz-Santana S Marquez E Del Nogal-Saez F Alvarez-Lerma F Martínez S Ferrer M Avellanas M Granada R Maraví-Poma E Albert P SierraR Vidaur L Ortiz P Prieto del Portillo I Galván B León-Gil C H1N1SEMICYUC Working Group | 2009 | Crit Care2009，13，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员