| 1 | Epidemiological Evolution of Lung Cancer in the South of Spain from 1990 to 2010显示文摘Background: Changes in lung cancer has been characterized by the increase of cases among women and the increase in adenocarcinomas among other histological subtypes.Methods: Descriptive analysis of cases diagnosed with lung cancer in Hospital Virgen de las Nieves(Spain) from 1990 to 2010,based on five variables(age, sex, smoking, histology and pathological anatomy). The study establishes associations between these variables and compares the results with the literature.Results: 2,026 patients were diagnosed with lung cancer in this period; 1,838 were males(90.7%) and 188 women(9.3%); 1,892 patients(93.4%) were smokers or ex-smokers and 134(6.6%) had never smoked; the most frequent non-small cell histology types were squamous cell carcinoma and adenocarcinoma and it was the most frequent neoplasia in women and were associated with a lower tobacco consumption.Conclusion: The large majority of lung cancer cases is associated with a history of smoking tobacco and there are histopathological differences according to gender and cumulative tobacco smoke load. | Alberto Caballero Vázquez Ana Dolores Romero Ortiz Jose Manuel González de Vega San Román Raimundo García del Moral Bernardino Alcázar Navarrete | 2018 | 中国肺癌杂志2018，21，1： | 17 |
| 4 | Pro-atherosclerotic markers and cardiovascular risk factors one year after liver transplantation显示文摘AIM:To investigate pro-atherosclerotic markers(endothelial dysfunction and inflammation)in patients one year after liver transplantation.METHODS:Forty-four consecutive liver transplant(LT)outpatients who were admitted between August2009 and July 2010,were followed-up by for 1 year,exhibited no evidences of infection or rejection,all of them underwent tacrolimus-based immunosuppressive regimens were consecutively enrolled.Inflammatory cytokines(TNFα,IFNγ,IL-8,and IL-10),endothelial biomarkers(sVCAM-1,sICAM-1,MPO,adiponectin,PAI-1,SAP,SAA,E-selectin,and MMP-9),high sensitive C-reactive protein,and Framingham risk score(FRS)were assessed.The anthropometric data,aminotransferases,metabolic syndrome features,glucose and lipid profiles,and insulin resistance data were also collected.The LT recipients were compared to 22 biopsy-proven non-alcoholic steatohepatitis(NASH)patients and 20healthy controls(non-obese,non-diabetics,and nondyslipidemic).RESULTS:The LT recipients had significantly younger ages and lower body mass indices,aminotransferases,fasting glucose and insulin levels,glucose homeostasis model and metabolic syndrome features than the NASH patients.Classic cardiovascular risk markers,such as Hs-CRP and FRS[2.0(1.0-8.75)],were lower in the LT patients compared to those observed in the NASH patients(P=0.009).In contrast,the LT recipients and NASH patients had similar inflammatory and endothelial serum markers compared to the controls(pg/mL):lower IL-10 levels(32.3 and 32.3 vs 62.5,respectively,P=0.019)and higher IFNγ(626.1 and 411.9 vs 67.9,respectively,P<0.001),E-selectin(48.5 and 90.03vs 35.7,respectively,P<0.001),sVCAM-1(1820.6and 1692.4 vs 1167.2,respectively,P<0.001),and sICAM-1(230.3 and 259.7 vs 152.9,respectively,P=0.015)levels.CONCLUSION:Non-obese LT recipients have similar pro-atherosclerotic serum profiles after a short 1-year follow-up period compared to NASH patients,suggesting a high risk of atherosclerosis in this population. | Mario Reis Alvares-da-Silva Claudia Pinto Marques Souza de Oliveira José Tadeu Stefano Hermes V Barbeiro Denise Barbeiro Francisco G Soriano Alberto Queiroz Farias Flair José Carrilho Luiz Augusto Carneiro D’Albuquerque | 2014 | World Journal of Gastroenterology2014，20，26： | 1 |
| 6 | Polarization shaping of Poincare´ beams by polariton oscillations显示文摘We propose theoretically and demonstrate experimentally the generation of light pulses whose polarization varies temporally to cover selected areas of the Poincare´sphere with both tunable swirling speed and total duration(1 ps and 10 ps,respectively,in our implementation).The effect relies on the Rabi oscillations of two polariton polarized fields excited by two counter-polarized and delayed pulses.The superposition of the oscillating fields result in the precession of the Stokes vector of the emitted light while polariton lifetime imbalance results in its drift from a circle of controllable radius on the Poincare´sphere to a single point at long times.The positioning of the initial circle and final point allows to engineer the type of polarization spanning,including a full sweeping of the Poincare´sphere.The universality and simplicity of the scheme should allow for the deployment of time-varying full-Poincare´polarization fields in a variety of platforms,timescales,and regimes. | David Colas Lorenzo Dominici Stefano Donati Anastasiia A Pervishko Timothy CH Liew Ivan A Shelykh Dario Ballarini Milena de Giorgi Alberto Bramati Giuseppe Gigli Elena del Valle Fabrice P Laussy Alexey V Kavokin Daniele Sanvitto | 2015 | Light(Science & Applications)2015，4，1： | 1 |
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