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4篇 您的检索式:作者名="Albrecht Bindereif"
    题名 作者 年代 出处 被引量
1Circular RNAs: Coding or noncoding?显示文摘Tim Schneider Albrecht Bindereif 2017Cell Research2017,27,6:1
2CircRNP complexes:from nature to design显示文摘Circular RNAs(circRNAs)have recently been established as a new and large class of noncoding RNAs,conserved in all eukaryotes investigated.However,functional and mechanistic investi-gations lag behind the rapid progress in circRNA expression studies,and no uniform function has emerged so far.Here,we focus on circRNA–protein(circRNP)complexes(circRNPs),since proteins associated with natural circRNAs likely guide us in the search for physiological functions of individual circRNAs.First,approaches for how to systematically search for circRNA-interacting proteins in natural circRNPs will be summarized,including some experimental considerations important for good scientific practice.Second,building on natural protein-sponging circRNAs,we introduce the concept of designer circRNAs functioning as specific protein sponges,using the heterogeneous nuclear ribonucleoprotein L(hnRNP L)and IMP3 proteins as two examples of classical RNA-binding proteins.Third,we discuss the general implications of this concept,in particular how it can be applied as a new way to intervene with RNA-based gene-regulatory networks.In sum,designer circRNAs sponging specific proteins open up exciting new perspectives in molecular medicine and on therapeutic options to treat human disease.Stephen Sukumar Nuthalapati Corinna Jessica Ulshofer Albrecht Bindereif 2023Journal of Molecular Cell Biology2023,15,1:0
3A joint adventure of Sino-German researchers to explore the wild world of RNAs显示文摘RNA biology has developed in recent years to a new emerging field,with new surprises and in sights ranging from basic mecha nisms to topics of clinical interest and opening up biotechnological applications in molecular medicine and novel therapeutic options.Here,we edit this Special Issue of Journal of Molecular Cell Biology on RNA biology,combining a series of reviews and research articles that reflect most of the current trends and topics emerging from recent Chinese-German interactions in RNA research.Albrecht Bindereif Zefeng Wang 2019Journal of Molecular Cell Biology2019,11,10:0
4Exo-endo trans splicing: a new way to link显示文摘Christian Preuβer Albrecht Bindereif 2013Cell Research2013,23,9:0
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