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您的检索式：作者名="Alessandro Cairo"
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| 1 | 现代视角下的历史美学 UKHOUSE大厅和地下室显示文摘UK House坐落在伦敦西区著名的牛津街,是一座多功能用途的标志性建筑。这座二级保护建筑建于1906年,并于1970年改建为办公大楼。建筑所保留的2个原始立面,展现了巴洛克风格的华丽装饰和爱德华时期所特有的精致细节,呈现建筑的复杂性和多样性以及古典而优雅的气息。富有历史感的立面给这座建筑带来了与众不同的气势,反映了一个充满野心、追求全球最高愿景的英国历史时期,这一时期对城市物质结构产生了重大影响。 | Emanuel Christ Christoph Gantenbein Tabea Lachenmann Loes Martens Alessandro Cairo Edward Nicholso Thomas Adank(摄影) 西竹(编译) | 2023 | 室内设计与装修2023，，6： | 0 |
| 2 | Potent trophic activity of spermidine supramolecular complexes in in vitro models显示文摘AIM:To test the growth-promoting activity of the polyamine spermidine bound to various polymeric compounds in supramolecular complexes.METHODS:A thiazolyl blue cell viability assay was used to determine the growth-promoting potency of spermidine-supramolecular complexes in a human skin fibroblast cell line exposed to spermidine and different spermidine-supramolecular complexes that were obtained by combining spermidine and polyanionic polymers or cyclodextrin.Reconstituted human vaginal epithelium was exposed to a specific spermidinesupramolecular complex,i.e.,spermidine-hyaluronan(HA)50,and cell proliferation was determined by Ki-67immunohistochemical detection.Transepithelial electrical resistance and histological analysis were also performed on reconstituted human vaginal epithelium to assess tissue integrity.RESULTS:The effect of spermidine and spermidinesupramolecular complexes was first tested in skin fi-broblasts.Spermidine displayed a reverse dose-related mode of activity with mmol/L growth inhibition,whereas 30%stimulation over basal levels was detected at mol/L and nmol/L levels.Novel spermidine-supramolecular complexes that formed between spermidine and polyanionic polymers,such as HA,alginate,and polymaleate,were then tested at variable spermidine concentrations and a fixed polymer level(0.1%w/v).Spermidine-supramolecular complexes stimulated the cell growth rate throughout the entire concentration range with maximal potency(up to 80%)at sub-mol/L levels.Similar results were obtained with spermidine-(-cyclodextrin),another type of spermidine-supramolecular complex.Moreover,the increased expression of Ki-67 in the reconstituted human vaginal epithelium exposed to spermidine-HA 50 showed that the mode of action behind the spermidine-supramolecular complexes was increased cell proliferation.Functional and morphological assessments of reconstituted human vaginal epithelium integrity did not show significant alterations after exposure to spermidine-HA,thus supporting its safety.CONCLUSION:Spermidine found in spermidine-supramolecular complexes displayed potentiated regenerative effects.Safety data on reconstituted human vaginal epithelium suggested that assessing spermidinesupramolecular complex efficacy in atrophic disorders is justified. | Carlo A Ghisalberti Alberto Morisetti Alessandro Bestetti Gaetano Cairo | 2013 | World Journal of Biological Chemistry2013，4，3： | 0 |
| 3 | UKHouse大厅改造显示文摘Christ&Gantenbein在伦敦完成的一座多功能建筑的新大堂改造设计,项目位于牛津街著名的西区,是市中心的地标。它是一座建于1906年的二级保护建筑,于1970年代改建为办公大楼。项目的两个原始立面得以保留,呈现出巴洛克式和爱德华七世元素的奇妙组合,而其他立面则是现代风格。爱德华七世时期的规模和宏伟的历史立面使这座建筑与众不同。Christ&Gantenbein改造后的空间,体现21世纪的企业架构愿景,大胆、未来主义、开放、交流,同时也历史悠久。宽敬的空间大堂入口处,设有镀古铜色金属的大窗户,与牛津街现有的外墙融为一体。镀铬不锈钢旋转门与内部的镜面柱相得益彰。 | Emanuel Christ Christoph Gantenbein Tabea Lachenmann Loes Martens Alessandro Cairo Edward Nicholson Thomas Adank(摄影) 舒禹(编译) | 2023 | 现代装饰2023，，1： | 0 |
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