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| 1 | Symposia Report Immunoglobulin G for the Treatment of Chronic Pain:Report of an Expert Workshop显示文摘背景:慢性疼痛的治疗效果仍不理想。尽管现在治疗慢性疼痛的药物种类较多,但许多患者对疗效仍不满意或诉药物的副作用太大。越来越多的证据表明,免疫系统参与了伤害性和神经病理性慢性疼痛的病理过程。设计:在英国利物浦的专题会议上,专家们出示了免疫系统参与慢性疼痛的证据。近来的研究表明,静脉(IVIg)或皮下(SCIg)注射免疫调节药物——多价免疫球蛋白(Ig G)可缓解外周神经病理性疼痛和其他疼痛性疾病。专题会议讨论了IVIg和SCIg治疗的适应证、效价比及其副作用。结果:Ig G可缓解某些伤害性和神经病理性慢性疼痛,如糖尿病、干燥综合征、纤维肌痛症、复杂性区域疼痛综合征、小儿麻痹后遗症和继发于病理性自身抗体的疼痛。结论:Ig G对某些慢性疼痛具有一定的治疗前景。Ig G是一种相对安全的治疗方法,副作用少而轻,但价格较贵。今后有必要对Ig G治疗顽固性疼痛进行随机对照研究和预测性临床试验。 | Stefano Tamburin Kristian Borg Xavier J. Caro Stefano Jann Alexander J. Clark Francesca Magrinelli Gen Sobue Lars Werhagen Giampietro Zanette Haruki Koike Peter J. Spath Angela Vincent Andreas Goebel | 2014 | 中国疼痛医学杂志2014，20，11： | 3 |
| 2 | The Antioxidant Activity of Coumarins and Flavonoids显示文摘 | Guilherme Borges Bubols Damiana da Rocha Vianna Alexander Medina-Remon Gilsane von Poser Rosa Maria Lamuela-Raventos Vera Lucia Eifler-Lima Solange Cristina Garcia | 2013 | Mini-Reviews in Medicinal Chemistry2013，，3： | 1 |
| 3 | Genomic variation in the MAP3K5 gene is associated with &bgr;-thalassemia disease severity and hydroxyurea treatment efficacy显示文摘 | Christina Tafrali Arsinoi Paizi Joseph Borg Milena Radmilovic Marina Bartsakoulia Emily Giannopoulou Olga Giannakopoulou Maja Stojiljkovic-Petrovic Branka Zukic Konstantinos Poulas Eleana F Stavrou Polyxeni Lambropoulou Alexandra Kourakli Alexander E Feli | 2013 | Pharmacogenomics2013，，5： | 1 |
| 4 | Right Ventricular Function Assessed by Two-Dimensional Strain and Tissue Doppler Echocardiography in Patients With Pulmonary Arterial Hypertension and Effect of Vasodilator Therapy显示文摘 | Adrian C. Borges Fabian Knebel Stephan Eddicks Alexander Panda Sebastian Schattke Christian Witt Gert Baumann | 2006 | The American Journal of Cardiology2006，，4： | 1 |
| 5 | Primary angioplasty for infarction due to isolated right ventricular artery occlusion显示文摘We report an unusual case of an isolated right ventricular infarction with haemodynamic compromise caused by spontaneous isolated proximal occlusion of the right ventricular branch of the right coronary artery(RCA), successfully treated by balloon angioplasty. A 58-yearold gentleman presented with epigastric pain radiating into both arms. Electrocardiograph with right ventricular leads confirmed ST elevation in V4 R and a diagnosis of isolated right ventricular infarction was made. Urgent primary percutaneous intervention was performed which revealed occlusion of the right ventricular branch of the RCA. During the procedure, the patient's blood pressure dropped to 80/40 mm Hg, and echocardiography showed impaired right ventricular systolic function. Despite aggressive fluid resuscitation, the patient remained hypotensive, continued to have chest pain and persistent electrocardiograph changes, and hence balloon angioplasty was performed on the proximal right ventricular branch which restored flow to the vessel and revealed a severe ostial stenosis. This was treated with further balloon angioplasty which restored TIMI 3 flow with resolution of patient's symptoms. Repeat echocardiography showed complete resolution of theST-elevation in leads V4 R and V5 R and partial resolution in V1. Subsequent dobutamine-stress echocardiography at 4 wk showed good left and right ventricular contractions. The patient was discharged after a 3-d inpatient stay without any complications. | Anwar A Chahal Min-Young Kim Alexander N Borg Yahya Al-Najjar | 2014 | World Journal of Cardiology2014，6，11： | 0 |
| 6 | 二尖瓣疾病显示文摘二尖瓣狭窄 病因学
二尖瓣狭窄(MS)几乎都是由于慢性风湿性心脏病所引起,尽管30%的患者没有明确的风湿热病史。风湿性MS的女性患者是男性患者的两倍。风湿性二尖瓣病变的发生率在发达国家中已经明显下降,但是在非洲、中东和亚洲地区,症状性二尖瓣病变可以累及十几岁以上的患者。 | Simon Ray Rhys Beynon Alexander Borg 陈益和(译) 纪宝华(校) | 2007 | 国际内科双语杂志(中英文)2007，7，4： | 0 |
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