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| 1 | Real time endoscopic ultrasound elastography and strain ratio in the diagnosis of solid pancreatic lesions显示文摘AIM To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions(SPL). METHODS A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area(A) representing the region of interest and area(B) representing the normal area. Area(B) was then divided by area(A). Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final diagnoses.RESULTS SPL were shown to be benign in 49 patients and malignant in 123 patients. Elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL. CONCLUSION Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL. | Hussein Okasha Shaimaa Elkholy Ramy El-Sayed Mohamed-Naguib Wifi Mohamed El-Nady Walid El-Nabawi Waleed A El-Dayem Mohamed I Radwan Ali Farag Yahya El-sherif Emad Al-Gemeie Ahmed Salman Mohamed El-Sherbiny Ahmed El-Mazny Reem E Mahdy | 2017 | World Journal of Gastroenterology2017，23，32： | 11 |
| 2 | Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging显示文摘BACKGROUND Chronic cocaine use is associated with stroke, coronary artery disease and myocardial infarction, resulting in severe impairments or sudden mortality. In the absence of clear cardiovascular symptoms, individuals with cocaine use disorder (iCUD) seeking addiction treatment receive mostly psychotherapy and psychiatric pharmacotherapy, with no attention to vascular disease (i.e., atherosclerosis). Little is known about the pre-clinical signs of cardiovascular risk in iCUD and early signs of vascular disease are undetected in this underserved population. AIM To assess inflammation, plaque burden and plaque composition in iCUD aiming to detect markers of atherosclerosis and vascular disease. METHODS The bilateral carotid arteries were imaged with positron emission tomography/magnetic resonance imaging (PET/MRI) in iCUD asymptomatic for cardiovascular disease, healthy controls, and individuals with cardiovascular risk. PET with 18F-fluorodeoxyglucose (18F-FDG) evaluated vascular inflammation and 3-D dark-blood MRI assessed plaque burden including wall area and thickness. Drug use and severity of addiction were assessed with standardized instruments. RESULTS The majority of iCUD and controls had carotid FDG-PET signal greater than 1.6 but lower than 3, indicating the presence of mild to moderate inflammation. However, the MRI measure of wall structure was thicker in iCUD as compared to the controls and cardiovascular risk group, indicating greater carotid plaque burden. iCUD had larger wall area as compared to the healthy controls but not as compared to the cardiovascular risk group, indicating structural wall similarities between the non-control study groups. In iCUD, wall area correlated with greater cocaine withdrawal and craving. CONCLUSION These preliminary results show markers of carotid artery disease burden in cardiovascular disease-asymptomatic iCUD. Broader trials are warranted to develop protocols for early detection of cardiovascular risk and preventive intervention in iCUD. | Keren Bachi Venkatesh Mani Audrey E Kaufman Nadia Alie Rita Z Goldstein Zahi A Fayad Nelly Alia-Klein | 2019 | World Journal of Radiology2019，11，5： | 2 |
| 3 | Inter-ethnic marriages and severity of coronary artery disease:A multicenter study of Arabian Gulf States显示文摘AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD. | Amin Daoulah Salem Al-kaabi Amir Lotfi Mushabab Al-Murayeh S Ali Nasseri Waleed Ahmed Salah N Al-Otaibi Mohamed N Alama Osama E Elkhateeb Amy J Plotkin Majed M Malak Khalid Alshali Mohamed Hamzi Saleh Al Khunein Mohammed Abufayyah Alawi A Alsheikh-Ali | 2017 | World Journal of Cardiology2017，9，4： | 2 |
| 4 | Optimization of Diesel,Methyl Tallowate and Ethanol Blend for Reducing Emissions from Diesel Engine显示文摘 | Ali Y Hanna M A Borg J E | 1995 | Bioresource Technology1995，52，： | 1 |
| 5 | Effect of fermentation on the in vitro protein digestibility of pearl millet显示文摘 | Ali MAM Tinay A H E Abdalla AH | 2003 | Food Chemistry2003，80，1： | 1 |
| 6 | Natural fibre high- density polyethylene and lead oxide composites for radi- ation shielding 显示文摘 | Abdo A E Ali M A M Ismail M R | 2003 | Radiation Physics and Chemistry2003，66，3： | 1 |
| 7 | Selective removal of some heavy metal ions from aqueous solution using treated polyethylene- g-styrene/maleic anhydride membranes显示文摘 | H A Abd El-Rehim E A Hegazy A E-H Ali | 2000 | React Funct Polym2000，43，： | 1 |
| 8 | Discreteness of space from the generalized uncertainty principle 显示文摘 | Ali A F Das S Vagenas E C | 2009 | Physics Letters B2009，678，5： | 1 |
| 9 | Synthesis and Sorption Behaviour of Some Radioactive Nuclides on Sodium Titanate as Cation Exchanger Adsorption显示文摘 | El-Naggar I M Mowafy E A Ali I M Aly H F | 2002 | Adsorption--Journal of the International Adsorption Society2002，8，： | 1 |
| 10 | Proposal for testing quantum gravi- ty in the lab显示文摘 | Ali A F Das S Vagenas E C | 2011 | Physical Review D2011，84，04： | 1 |
| 11 | Dual Doped High Tg White Organic Light Emitting Devices on Silicon显示文摘 | Ali T A Jones G W Howard W E | 2004 | SID2004，29，： | 1 |
| 12 | 显示文摘 | Milovzorov D E Ali A M Inokuma T | 2001 | Thin Solid Films2001，382，： | 1 |
| 13 | Deep desulp Hurzation of gasoline and diesel fuels using non-hydrogen consuming techniques显示文摘 | ALI M F MALKI A A ALI B E | 2006 | Fuel2006，85，1011： | 1 |
| 14 | Determination of selected polychlorinated biphenyls in soil by miniaturised ultrasonic solvent extraction and gas chromatography-mass-selective detection显示文摘 | MEHMET E A ALI T SENAR O | 2006 | Anal Chim Acta2006，577，2： | 1 |
| 15 | Determination of selected polychlorinated biphenyls in soil by miniaturised ultrasonic solven textraction and gas chromatography mass selective detection显示文摘 | Mehmet E A Ali T Senar O | 2006 | Analytica Chmiica Acta2006，577，： | 1 |
| 16 | CD56 expression of neuroendocflne neoplasms on immunophenotyping by flow eytometry:a novel diagnostic approaeh to fine-needle aspiration biopsy显示文摘 | Farinola M A Weir E G Ali S Z | | 0，，4： | 1 |
| 17 | Biological importance of marine algae显示文摘 | Gamal E Ali A | 2010 | Saudi Pharmaceutical Journal2010，18，1： | 1 |
| 18 | An optimum transformation for somatic cell content ration in milk 显示文摘 | Ali A K A Shook G E | 1980 | J Dairy Sci1980，63，： | 1 |
| 19 | An efficient low complexity lossless coding algorithm for medical images显示文摘 | Ghrare S E Ali M A M Jumari K | 2009 | American Journal of Applied Sciences2009，6，8： | 1 |
| 20 | Investigation of dimpled fins for heat transfer enhancement in compact heat exchangers 显示文摘 | Mohammad A E Ali R Daoesh K T | 2008 | International Journal of Heat and Mass Transfer2008，51，： | 1 |
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