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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Transport and transformation of dissolved and particulate materials on conti- nental margins influenced by major rivers: benthic boundary layer and seabed processes 显示文摘 | Mekee B A Aller R C Allison M A | 2004 | Continental Shelf Research2004，24，78： | 1 |
| 3 | Patterns in nutrient availability and plant diversity of temperate north America wetlands显示文摘 | BEDFORD L B WALBRIDGE M R ALLISON A | 1999 | Ecology1999，80，7： | 1 |
| 4 | Patterns in nutrient availability and plant diversity of temperate North American wetlands显示文摘 | Barbara L B Mark RW Allison A | 1999 | Ecology1999，7，： | 1 |
| 5 | Droughts, floods andfreshwater ecosystems : Evaluating climate change impacts anddeveloping adaptation strategies显示文摘 | Allison A Fitzsimons J Richter B | 2011 | Marine and freshwaterreseach2011，62，3： | 1 |
| 6 | Patterns of Carti- lage Structural Protein Loss in Human Tracheal Stenosis 显示文摘 | Leila A Mankarious MD Allison B | 2002 | Laryngoscope2002，112，6： | 1 |
| 7 | Single mutations in the VP2 300 loop resion of the three-fold spike of the carnivore parvovirus eapsid can determine host range 显示文摘 | Allison A B Organtini L J Zhang S | 2015 | J Virel2015，90，2： | 1 |
| 8 | Inhibition of protein kinase C-beta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans显示文摘 | Joshua A B Allison B G Mary B G | 2002 | Circ Res2002，90，： | 1 |
| 9 | Patterns in nutrient availability and plant diversity of temperate North American wetlands 显示文摘 | Barbara L B Mark R W and Allison A | 1999 | Ecology1999，7，： | 1 |
| 10 | Aging and energetics' 'Top 40' future research opportunities 2010 2013显示文摘 | ALLISON D B ANTOINE L H BALLINGER S W et a l | 2014 | F1000 Res2014，，3： | 1 |
| 11 | Potential for phytoremediation of polychlorinated biphenyl-(PCB)-contaminated soil显示文摘 | Zeeb A B Amphlett S J Allison R | 2006 | International Journal of Phytoremediation2006，8，3： | 1 |
| 12 | Associations of physical activ- ity and sedentary behavior with regional fat deposition显示文摘 | Larsen B A Allison M A Kang E | 2014 | Med Sci Sports Exerc2014，46，3： | 1 |
| 13 | Proteomic profiling and neuro-degeneration in West-Nile-virus-infected neurons显示文摘 | DHINGRA V LI Q ALLISON A B | 2005 | J Biomed Biotechnol2005，2005，3： | 1 |
| 14 | Oxidative stress following traumatic brain injury: enhancement of endogenous antioxidant defense systems and the promise of improved outcome 显示文摘 | Eghwrudjakpor P O Allison A B | 2010 | Niger J Med2010，19，1： | 1 |
| 15 | The impact of weight gain on quality of life among persons with schizophrenia显示文摘 | Allison D B Mackell J A McDonnell D D | 2003 | Ps ychiatr Serv2003，54，4： | 1 |
| 16 | Oxygen-17 Nuclear Magnetic Resonance Spectroscopic Study of Substituted Benzanilides and Salicylanilides显示文摘 | Nowak-Wydra B Allison L W Kumar A | 1994 | J Chem Research Synop1994，66，12： | 1 |
| 17 | The search for human obesity genes显示文摘 | ALLISON D B | 1998 | Science1998，280，： | 1 |
| 18 | Proteomic profiling and neurodegeneration in west-nile-virus-infected neurons显示文摘 | DHING RA V LI Q J ALLISON A B | 2005 | J Biomed Biotech2005，，3： | 1 |
| 19 | The impact of weight gain on quality of life among persons with schizophrenia显示文摘 | Allison D B Mackell J A McDonnell D D | | 0，，04： | 1 |
| 20 | A water and sedi- ment budget for the lower Mississippi-Atchafalaya River in flood years 2008-2010: Implications for sediment discharge to the oceans and coastal restoration in Louisiana显示文摘 | Allison M A Demas C H Ebersole B A | 2012 | Joumal of Hy- drology2012，43，： | 1 |
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