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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Antipsychotic- induced weight gain:a comprehensive research synthesis显示文摘 | ALLISON D B MENTORE J L HEO M | 1999 | Am J Psychiatry1999，156，11： | 1 |
| 3 | Patterns in nutrient availability and plant diversity of temperate north America wetlands显示文摘 | BEDFORD L B WALBRIDGE M R ALLISON A | 1999 | Ecology1999，80，7： | 1 |
| 4 | Equivalent wind-erosion protection fi'om selected crop residues显示文摘 | Lyles L Allison B E | 1981 | Transactions of the ASAE1981，24，： | 1 |
| 5 | Patterns in nutrient availability and plant diversity of temperate North American wetlands显示文摘 | Barbara L B Mark RW Allison A | 1999 | Ecology1999，7，： | 1 |
| 6 | CFTC and SEC Jointly Adopt Final Swap Entity Definition Rules显示文摘 | Allison L Bruce B | 2012 | Joumal of Investment Compliance2012，13，3： | 1 |
| 7 | Antipsychotic -- induced weight gain a comprehensive research synthesis显示文摘 | Allison D B Mentore J L Heo M | 1999 | Am J Psychiat1999，156，11： | 1 |
| 8 | Single mutations in the VP2 300 loop resion of the three-fold spike of the carnivore parvovirus eapsid can determine host range 显示文摘 | Allison A B Organtini L J Zhang S | 2015 | J Virel2015，90，2： | 1 |
| 9 | Congenital Melanocytic Nevus and the Internet:an Evaluation of Available Web-based Resources显示文摘 | Allison L David B | 2005 | The Journal of Craniofacial Surgery2005，16，5： | 1 |
| 10 | Patterns in nutrient availability and plant diversity of temperate North American wetlands 显示文摘 | Barbara L B Mark R W and Allison A | 1999 | Ecology1999，7，： | 1 |
| 11 | Aging and energetics' 'Top 40' future research opportunities 2010 2013显示文摘 | ALLISON D B ANTOINE L H BALLINGER S W et a l | 2014 | F1000 Res2014，，3： | 1 |
| 12 | Equivalent wind-erosion protection from selected crop residues显示文摘 | Lyles L Allison B E | 1981 | Transactions of the ASAE1981，24，2： | 1 |
| 13 | Equivalent wind-erosion protection from selected crop residues显示文摘 | Lyles L Allison B E | 1981 | Transactions of the ASAE1981，24，2： | 1 |
| 14 | Wind erosion: the protective role of simulated standing stubble 显示文摘 | Lyles L Allison B E | 1976 | Transactions of the ASAE1976，19，1： | 1 |
| 15 | Estimated intakes of trans fatty and other fatty acids in the US population 显示文摘 | ALLISON D B EGAN S K BARF | 1999 | J Am Diet Assoc1999，99，： | 1 |
| 16 | Wind erosion: the protective role ofsimulated standing stubble显示文摘 | Lyles L Allison B E | 1976 | Transactions of AmericanSociety of Agricultural Engineers1976，19，1： | 1 |
| 17 | Oxygen-17 Nuclear Magnetic Resonance Spectroscopic Study of Substituted Benzanilides and Salicylanilides显示文摘 | Nowak-Wydra B Allison L W Kumar A | 1994 | J Chem Research Synop1994，66，12： | 1 |
| 18 | Overestimation of soybean crop transpiration by sap-flow measurements under field conditions in Cen- tral Portugal显示文摘 | Gerdes G Allison B E Pereira L S | 1994 | Irrigation Science1994，14，： | 1 |
| 19 | patterns in nutrient availability and plant diversity of tem- perate north Ameriean wetlands显示文摘 | BARBARA L B MARK R W ALLISON A | 1999 | Ecology1999，80，7： | 1 |
| 20 | Pattems in nutrient availability and plant diversity of temperate North American wetlands 显示文摘 | Barbara L B Mark RWand Allison A | 1999 | Ecology1999，7，： | 1 |
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