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| 1 | Perioperative and renal functional outcomes of elective robot‐assisted partial nephrectomy ( RAPN ) for renal tumours with high surgical complexity显示文摘 | Alessandro Volpe Diletta Garrou Daniele Amparore Geert De Naeyer Francesco Porpiglia Vincenzo Ficarra Alexandre Mottrie | 2014 | BJU Int2014，，： | 2 |
| 2 | Margins, ischaemia and complications rate after laparnscopic partial nephrectomy: impact of learning curve and tumour anatomical characteristics 显示文摘 | Porpiglia F Bertolo R Amparore D | 2013 | BJU Int2013，112，8： | 1 |
| 3 | Mini- retroperitoneoscopic clamplcss partial nephrectomy for 'low-complexity' renal turnouts (PADUA score ≤ 8) 显示文摘 | Porpig/ia F Bertolo R Amparore D | 2014 | Eur Urol2014，66，4： | 1 |
| 4 | 显示文摘 | Foix D Serra A Amparore L | 2012 | Polymer2012，53，： | 1 |
| 5 | Treatment outcomes of partial nephrectomy for Tlb turnouts显示文摘 | Volpe A Amparore D Mottrie A | 2013 | Curr Opin Urol2013，23，5： | 1 |
| 6 | Impact resistance enhancement by adding epoxy ended hyperbranched polyester to DGEBA photocured thermosets显示文摘 | Foix D Serra A Amparore L | 2012 | Polymer2012，53，15： | 1 |
| 7 | Impact resistance enhancement by adding epoxy ended hyperbranched polyester to DGEBA photocured thermosets显示文摘 | Foix D Serra A Amparore L | 2012 | Polymer2012，53，15： | 1 |
| 8 | Impact resistance enhancement by adding epoxy ended hyperbranched polyester to DGEBA photocured therrnosets显示文摘 | Foix D Serra A Amparore L | 2012 | Polymer2012，53，： | 1 |
| 9 | Treatment outcomes of partial nephrectomy for T1b tumours显示文摘 | VOLPE A AMPARORE D MOTTRIE A | 2013 | Curr Opin Urol2013，23，5： | 1 |
| 10 | Potential benefit of lymph node dissection during radical nephrectomy for kidney cancer:A review and critical analysis of current literature显示文摘Objective:The role of lymph node dissection(LND)is still controversial in patients with renal cell carcinoma undergoing surgery.We aimed to provide a comprehensive review of the literature about the effect of LND on survival,prognosis,surgical outcomes,as well as patient selection and available LND templates.Methods:Recent literature(from January 2011 to December 2021)was assessed through PubMed and MEDLINE databases.A narrative review of most relevant articles was provided.Results:The frequencies in which LNDs are being carried out are decreasing due to an increase in minimally invasive and nephron sparing surgery.Moreover,randomized clinical trials and meta-analyses failed to show any survival advantage of LND versus no LND.However,retrospective studies suggest a survival benefit of LND in high-risk patients(bulky tumors,T3-4 stage,and cN1 patients).Moreover,extended LND might provide important staging information,which could be of interest for adjuvant treatment planning.Conclusion:No level 1 evidence of any survival advantage deriving from LND is currently available in literature.Thus,the role of LND is limited to staging purposes.However,low grade evidence suggests a possible role of LND in high-risk patients.Randomized clinical trials are warranted to corroborate these findings. | Michele Marchioni Daniele Amparore Igino Andrea Magli Riccardo Bertolo Umberto Carbonara Selcuk Erdem Alexandre Ingels Constantijn H.J.Muselaers Onder Kara Marco Mascitti Tobias Klatte Maximilian Kriegmair Nicola Pavan Eduard Roussel Angela Pecoraro Laura Marandino Riccardo Campi Luigi Schips | 2022 | Asian Journal of Urology2022，9，3： | 1 |
| 11 | Three-dimensional imaging reconstruction of the kidney’s anatomy for a tailored minimally invasive partial nephrectomy:A pilot study显示文摘Objective:The aim of the study was to evaluate three-dimensional virtual models(3DVMs)usefulness in the intraoperative assistance of minimally-invasive partial nephrectomy in highly complex renal tumors.Methods:At our institution cT1-2N0M0 all renal masses with Preoperative Aspects and Dimensions Used for an Anatomical classification score≥10 treated with minimally-invasive partial nephrectomy were considered for the present study.For inclusion a baseline contrast-enhanced computed tomography in order to obtain 3DVMs,the baseline and postoperative serum creatinine as well as estimated glomerular filtration rate values were needed.These patients,in which 3DVMs were used to assist the surgeon in the planning and intraoperative guidance,were then compared with a control group of patients who underwent minimally-invasive partial nephrectomy with the same renal function assessments,but without 3DVMs.Multivariable logistic regression models were used to predict the margin,ischemia,and complication score achievement.Results:Overall,79 patients met the inclusion criteria and were compared with 143 complex renal masses without 3DVM assistance.The 3DVM group showed better postoperative outcomes in terms of baseline-weighted differential estimated glomerular filtration rate(-17.7%vs.-22.2%,p=0.03),postoperative complications(16.5%vs.23.1%,p=0.03),and major complications(Clavien Dindo>III,2.5%vs.5.6%,p=0.03).At multivariable logistic regression 3DVM assistance independently predicted higher rates of successful partial nephrectomy(odds ratio:1.42,p=0.03).Conclusion:3DVMs represent a useful tool to plan a tailored surgical approach in case of surgically complex masses.They can be used in different ways,matching the surgeon's needs from the planning phase to the demolitive and reconstructive phase,leading towards maximum safety and efficacy outcomes. | Daniele Amparore Angela Pecoraro Federico Piramide Paolo Verri Enrico Checcucci Sabrina De Cillis Alberto Piana Mariano Burgio Michele Di Dio Matteo Manfredi Cristian Fiori Francesco Porpiglia | 2022 | Asian Journal of Urology2022，9，3： | 1 |
| 12 | Treatment outcomes of partial ne- phrectomy for T1 b tumours 显示文摘 | Volpe A Amparore D Mottrie A | 2013 | Curr Opin Urol2013，23，5： | 1 |
| 13 | Three-dimensional automatic artificial intelligence driven augmented-reality selective biopsy during nerve-sparing robot-assisted radical prostatectomy:A feasibility and accuracy study显示文摘Objective:To evaluate the accuracy of our new three-dimensional(3D)automatic augmented reality(AAR)system guided by artificial intelligence in the identification of tumour’s location at the level of the preserved neurovascular bundle(NVB)at the end of the extirpative phase of nerve-sparing robot-assisted radical prostatectomy.Methods:In this prospective study,we enrolled patients with prostate cancer(clinical stages cT1ce3,cN0,and cM0)with a positive index lesion at target biopsy,suspicious for capsular contact or extracapsular extension at preoperative multiparametric magnetic resonance imaging.Patients underwent robot-assisted radical prostatectomy at San Luigi Gonzaga Hospital(Orbassano,Turin,Italy),from December 2020 to December 2021.At the end of extirpative phase,thanks to our new AAR artificial intelligence driven system,the virtual prostate 3D model allowed to identify the tumour’s location at the level of the preserved NVB and to perform a selective excisional biopsy,sparing the remaining portion of the bundle.Perioperative and postoperative data were evaluated,especially focusing on the positive surgical margin(PSM)rates,potency,continence recovery,and biochemical recurrence.Results:Thirty-four patients were enrolled.In 15(44.1%)cases,the target lesion was in contact with the prostatic capsule at multiparametric magnetic resonance imaging(Wheeler grade L2)while in 19(55.9%)cases extracapsular extension was detected(Wheeler grade L3).3D AAR guided biopsies were negative in all pathological tumour stage 2(pT2)patients while they revealed the presence of cancer in 14 cases in the pT3 cohort(14/16;87.5%).PSM rates were 0%and 7.1%in the pathological stages pT2 and pT3(<3 mm,Gleason score 3),respectively.Conclusion:With the proposed 3D AAR system,it is possible to correctly identify the lesion’s location on the NVB in 87.5%of pT3 patients and perform a 3D-guided tailored nerve-sparing even in locally advanced diseases,without compromising the oncological safety in terms of PSM rates. | Enrico Checcucci Alberto Piana Gabriele Volpi Pietro Piazzolla Daniele Amparore Sabrina De Cillis Federico Piramide Cecilia Gatti Ilaria Stura Enrico Bollito Federica Massa Michele Di Dio Cristian Fiori Francesco Porpiglia | 2023 | Asian Journal of Urology2023，10，4： | 0 |
| 14 | Current strategies to diagnose and manage positive surgical margins and local recurrence after partial nephrectomy显示文摘Objective:No standard strategy for diagnosis and management of positive surgical margin(PSM)and local recurrence after partial nephrectomy(PN)are reported in literature.This review aims to provide an overview of the current strategies and further perspectives on this patient setting.Methods:A non-systematic review of the literature was completed.The research included the most updated articles(about the last 10 years).Results:Techniques for diagnosing PSMs during PN include intraoperative frozen section,imprinting cytology,and other specific tools.No clear evidence is reported about these methods.Regarding PSM management,active surveillance with a combination of imaging and laboratory evaluation is the first option line followed by surgery.Regarding local recurrence management,surgery is the primary curative approach when possible but it may be technically difficult due to anatomy resultant from previous PN.In this scenario,thermal ablation(TA)may have the potential to circumvent these limitations representing a less invasive alternative.Salvage surgery represents a valid option;six studies analyzed the outcomes of nephrectomy on local recurrence after PN with three of these focused on robotic approach.Overall,complication rates of salvage surgery are higher compared to TA but ablation presents a higher recurrence rate up to 25%of cases that can often be managed with repeat ablation.Conclusion:Controversy still exists surrounding the best strategy for management and diagnosis of patients with PSMs or local recurrence after PN.Active surveillance is likely to be the optimal first-line management option for most patients with PSMs.Ablation and salvage surgery both represent valid options in patients with local recurrence after PN.Conversely,salvage PN and radical nephrectomy have fewer recurrences but are associated with a higher complication rate compared to TA.In this scenario,robotic surgery plays an important role in improving salvage PN and radical nephrectomy outcomes. | Umberto Carbonara Daniele Amparore Cosimo Gentile Riccardo Bertolo Selcuk Erdem Alexandre Ingels Michele Marchioni Constantijn H.J.Muselaers Onder Kara Laura Marandino Nicola Pavan Eduard Roussel Angela Pecoraro Fabio Crocerossa Giuseppe Torre Riccardo Campi Pasquale Ditonno | 2022 | Asian Journal of Urology2022，9，3： | 0 |
| 15 | Reply to Grange PC,Morris PT,Benz HL,Buggele WA,Fryrear RS.Letter to the editor re:Amparore D,Pecoraro A,Piramide F,Verri P,Checcucci E,De Cillis S,et al.Three-dimensional imaging reconstruction of the kidney’s anatomy for a tailored minimally invasive partial nephrectomy:A pilot study.Asian J Urol 2022;9:263-71.A further step towards personalized surgery through virtual clip application显示文摘Dear Editor,We read with great interest the Letter relative to our recently published article on the role of three-dimensional(3D)imaging reconstruction of the kidney’s anatomy for the management of minimally invasive partial nephrectomy[1].We thank the Authors for the discussion points that they have raised,giving us the possibility to explain more in details the methodological draw of the study as well as to introduce some new steps in the evolution of 3D virtual models(3DVMs). | Angela Pecoraro Daniele Amparore | 2023 | Asian Journal of Urology2023，10，1： | 0 |
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