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		题名	作者	年代	出处	被引量
	1	Decomposition and removal of dental model plaque by using toothpaste containing dextranase显示文摘Objective:The purpose of this study is to demonstrate the decomposition and removal effects of dextranase-containing toothpaste on dental plaque. Method:In the decomposition test,the supernatant of three times diluted toothpaste was applied to a dextran solution (as a dental model plaque),and samples were evaluated by colorimetric reaction with Fehling’s test solution. In the removal test,the supernatant of three times diluted toothpaste was applied to a dental model plaque prepared with Streptococcus mutans and the optical density at 550nm (hereinafter referred to as OD_(550)) was measured as the remaining plaque. Results:In the test solution of toothpaste containing dextranase,a red-brown precipitate was observed. On the other hand,a precipitate was not observed in the test solution of the placebo toothpaste which did not contain dextranase. The plaque removal effect of the test toothpaste was 2. 7 times higher than that of the placebo toothpaste. Conclusion:Our findings suggest that the test toothpaste containing dextranase has a higher plaque removal effect by cuttingα-1,6-linkages inside the plaque. Therefore,the test toothpaste might be helpful to prevent dental caries.	Yuko Aoki Zheng Sujiang Yasuo Nomura Kenichiro Shibasaki Gotaro Iiizumi Liu Jing Li Debao An Fengbao	2018	口腔护理用品工业2018，28，4：	0

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