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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Application of purge and trap extraction and gas chromatography for determination of minor esters in cider显示文摘 | ROBERTO R M NOEM P G ANA G H | 2005 | Journal of chromatography A2005，1069，2： | 1 |
| 3 | Structural and optical properties of polypropylene-montmorillonite nanocomposites显示文摘 | Lucilene B P Ana T M Thiago R G | 2007 | Materials Science and Engineering A2007，447，12： | 1 |
| 4 | Renal impairment and heart failure with preserved ejection fraction early post-myocardial infarction显示文摘AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (IRAs) between 1 to 28 d after myocardial infarction (MI) were grouped into chronic kidney disease (CKD) stages based on estimated glomerular filtration rate (eGFR).Rates of early post-MI HF were compared among eGFR groups.Logistic regression was used to explore independent predictors of HF.RESULTS:Reduced eGFR was present in 71.1% of 2160 patients,with significant renal impairment (eGFR < 60 mL/min every 1.73 m2) in 14.8%.The prevalence of HF was higher with worsening renal function:15.5%,17.8% and 29.4% in patients with CKD stages 1,2 and 3 or 4,respectively (P < 0.0001),despite a small absolute difference in mean EF across eGFR groups:48.2 ± 10.0,47.9 ± 11.3 and 46.2 ± 12.1,respectively (P=0.02).The prevalence of HF was again higher with worsening renal function among patients with preserved EF:10.1%,13.6% and 23.6% (P < 0.0001),but this relationship was not significant among patients with depressed EF:27.1%,26.2% and 37.9% (P= 0.071).Moreover,eGFR was an independent correlate of HF in patients with preserved EF (P=0.003) but not in patients with depressed EF (P=0.181).CONCLUSION:A significant proportion of post-MI patients with occluded IRAs have impaired renal function.Impaired renal function was associated with an increased rate of early post-MI HF,the association being strongest in patients with preserved EF.These findings have implications for management of peri-infarct HF. | Vinod Jorapur Gervasio A Lamas Zygmunt P Sadowski Harmony R Reynolds Antonio C Carvalho Christopher E Buller James M Rankin Jean Renkin Philippe Gabriel Steg Harvey D White Carlos Vozzi Eduardo Balcells Michael Ragosta C Edwin Martin Vankeepuram S Srinivas William W Wharton III Staci Abramsky Ana C Mon Shari S Kronsberg Judith S Hochman | 2010 | World Journal of Cardiology2010，2，1： | 1 |
| 5 | Analytical characterization ofalcohol-ethoxylate substances by instrumental separation techniques 显示文摘 | Maria R P Ana M C Angel R | 2011 | Trends in Analytical Chemistry2011，30，7： | 1 |
| 6 | Pulsed electric fields effects on the molecular structure and gelation of βlactoglobulin concentrate and egg white 显示文摘 | Oscar E P Ana M R P | 2004 | Food Research International2004，37，： | 1 |
| 7 | Arabidopsis and tobacco plants ectopically expressing the soybean antiquitin-like ALDH7 gene display enhanced tolerance to drought,salinity,and oxidative stress显示文摘 | Simone M R Maxuel O A Ana P S G Fabio M D Maria C B P Elizabeth P B F | | 0，，： | 1 |
| 8 | Development and validation of a fast high-performance liquid chromatography method for the determination of microcncapsulated pyrethroid pesticides显示文摘 | ISABEL P R GIL-ALEGRE M E ANA ISABEL T S | 2006 | Analytica Chirnica Acta2006，557，12： | 1 |
| 9 | Effects of soybean Kunitz trypsin inhibitor on the cotton boll weevil (Anthonomus grandis)显示文摘 | FRANCOA O L DIASB S C MAGALHA_ESD C P MONTEIROA ANA C S JR C B MELOE F R OLIVEIRA-NETOA O B MONNERATA R G GROSSI-DE-SA M F | 2004 | Phytochernistry2004，65，1： | 1 |
| 10 | Organoclays:Properties,preparation and applications显示文摘 | Lucilene B P Ana R M Francisco R | 2008 | Applied Clay Science2008，42，12： | 1 |
| 11 | Influence of insoluble dietary cellulose on digestive enzyme activity, feed digestibility and survival in the red claw crayfish, Cherax quadricarinatus (von Martens)显示文摘 | Ana P Neil A R Peter B M | 2006 | Aquac Res2006，37，： | 1 |
| 12 | Optimizationof J3-glucosidase, |3-xylosidase and xylanase produc-tion by colletotrichum graminicoLa under solid-statefermentation and application in raw sugarcane trashsaccharification 显示文摘 | Ana L R L Z Cesar S?Luana P M | 2013 | Int J Mol Sci2013，14，2： | 1 |
| 13 | Physicochemical and biochemical characterization of starch granules isolated of pigmented maize hybrids显示文摘 | Edith A Ana P B R Guadalupe M | 2008 | Starch2008，60，8： | 1 |
| 14 | 显示文摘 | Ana M P Osvaldo A S Marian R D | 2004 | Journal of Alloys and Compounds2004，374，： | 1 |
| 15 | A novel approach for the oxidative catalysis employing polyoxometalate-laccase system:application to the oxygen bleaching of Kraft pulp显示文摘 | Ana P M Tavares Jose A F Gamelas Armindo R Gaspar | 2004 | Catalysis Communications2004，，5： | 1 |
| 16 | Release of NO from a nitrosyl ruthenium complexthrough oxidation of mitochondrial NADH and effects onmitochondria 显示文摘 | Femando P Rodrigues Cezar R Pestana Ana C M Polizello | 2012 | Nitric Oxide2012，26，13： | 1 |
| 17 | The rootstock effect on the tomato salinity response depends on the shoot genotype显示文摘 | ANA S C MARIA M M R FRANCISCO P A | 2002 | Plant Science2002，162，： | 1 |
| 18 | Influence of Maillard conjugation on structural characteristics and rheological properties of whey protein/dextran systems 显示文摘 | Maria J S Mafia J M Ana M R P | 2014 | Food Hydrocolloids2014，39，： | 1 |
| 19 | J Chromatogr A显示文摘 | Stoj anka V Bilj ana S Jelena V Ljilgana P A Goran R Dragan M | 2008 | 1202 (2) : 1552008，1202，2： | 1 |
| 20 | c-Myc proteinis stabilized by fibroblast grow th factor 2 and destabilizedby ACTH to control cell cycle in mouse Y1 adrenocorti-cal cells显示文摘 | Ana P L Miriam S M Katia M R | 2004 | J Mol Endocrinol2004，33，3： | 1 |
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