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| 1 | Vanishing bile duct syndrome in human immunodeficiency virus infected adults:A report of two cases显示文摘Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with medications,autoimmune disorders,cancer,transplantation,and infections,the specific mechanisms of disease are not known.To date,only 4 cases of VBDS have been reported in human immunodeficiency virus(HIV) infected patients.We report 2 additional cases of HIV-associated VBDS and review the features common to the HIV-associated cases.Presentation includes hyperbilirubinemia,normal liver imaging,and negative viral and autoimmune hepatitis studies.In HIV-infected subjects,VBDS occurred at a range of CD4+ T-cell counts,in some cases following initiation or change in antiretroviral therapy.Lymphoma was associated with two cases;nevirapine,antibiotics,and viral co-infection were suggested as etiologies in the other cases.In HIV-positive patients with progressive cholestasis,early identification of VBDS and referral for transplantation may improve outcomes. | Ana Paula Oppenheimer Christopher Koh Mary McLaughlin John C Williamson Thomas D Norton Jennifer Laudadio Theo Heller David E Kleiner Kevin P High Caryn G Morse | 2013 | World Journal of Gastroenterology2013，19，1： | 8 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Combined drug screening and confirmation by liquid chromatography time-of-flight mass spectrometry with reverse database search显示文摘 | Ana de C Merja G stman P | 2012 | Anal and Bioanal Chem2012，403，5： | 1 |
| 4 | Arabidopsis and tobacco plants ectopically expressing the soybean antiquitin-like ALDH7 gene display enhanced tolerance to drought,salinity,and oxidative stress显示文摘 | Simone M R Maxuel O A Ana P S G Fabio M D Maria C B P Elizabeth P B F | | 0，，： | 1 |
| 5 | Effects of soybean Kunitz trypsin inhibitor on the cotton boll weevil (Anthonomus grandis)显示文摘 | FRANCOA O L DIASB S C MAGALHA_ESD C P MONTEIROA ANA C S JR C B MELOE F R OLIVEIRA-NETOA O B MONNERATA R G GROSSI-DE-SA M F | 2004 | Phytochernistry2004，65，1： | 1 |
| 6 | Glutathione-mediated cadmium sequestration in Rhizobium leguminosarum显示文摘 | Ana I G L Sofia C C Etelvina M A P F | 2006 | Enzyme and Microbial Technology2006，39，4： | 1 |
| 7 | EDDS and EDTA-enhanced zinc accumulation by solanum nig- rum inoculated with arbuscular mycorrhizal fungi grown in contaminated soil显示文摘 | Ana P G C Marques Rui S Oliveira Kalina A Samardjieva | 2008 | Chemosphere2008，70，6： | 1 |
| 8 | Chromosome number in Bromeliaceae显示文摘 | Ana L P C José G A A Moema C B Jorge C S A Maria L S G | 2000 | Genetic and Molecular Biology2000，23，1： | 1 |
| 9 | Removal of heavy metals using different polymer matrixes as support for bacterial immobilization显示文摘 | Carlos P Ana P G C Marquesa A G | 2011 | Journal of Hazardous Materials2011，，191： | 1 |
| 10 | In vivo growth-inhibition of Sarcoma180 by an α-(1→4)-glucan-β-(1 →6)-glucan-protein complex polysaccharide obtained from Agaricus blazei Murill显示文摘 | MARIA L C G DANIEL P B ANA P N N A | 2009 | J Nat Med2009，63，： | 1 |
| 11 | Action of Microbial Transglutaminase (MTGase) in the Modification of Food Proteins : A Review 显示文摘 | Ana L C G Silvana P D G F | 2015 | Food Chem2015，171，2： | 1 |
| 12 | Glutathione-mediated cadmium sequestration in Rhizobium leguminosarum显示文摘 | Ana I G L Sofia C C Etelvina M A P F | 2006 | Enzyme and Microbial Technology2006，39，4： | 1 |
| 13 | Ice-cream as a probiotic food carrier显示文摘 | Adriano G Cruz Adriane E C Antunes Ana Lucia O P Sousa | 2009 | Food Research International2009，，42： | 1 |
| 14 | Vaccination against Taenia solium cysticercosis in pigs using native and recombinant oncosphere antigens显示文摘 | Agustin P Ana F Charles G C | 1999 | Int J Parasiol1999，，29： | 1 |
| 15 | Roles of climacteric ethylene in the development of chilling injury in plums 显示文摘 | Ana P C Jordi G Christian L | 2008 | Postharvest Biology and Technology2008，47，： | 1 |
| 16 | Antigenic and genomic relation detween human influenza A (H3N2) viruses circulating in Argentina during 1998 and the H3N2 vaccine component显示文摘 | Andrea V P Elsa G B Ana M C | 2001 | Rev Panam Salud Publica2001，4，： | 1 |
| 17 | Chromosome number in Brome liaeeae 显示文摘 | Ana L P C Josd G A A Moema C B | 2000 | Genetic and Molecular Biology2000，23，1： | 1 |
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