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| 1 | Successfulpreoperative localizationof a small pancreatic Insulinoma by diffusion-weightedMRI显示文摘 | Anass A Anne M Jean C | 2009 | JPancreas (Online)2009，10，5： | 1 |
| 2 | Hepatobiliary manifestations following two-stages elective laparoscopic restorative proctocolectomy for patients with ulcerative colitis:A prospective observational study显示文摘BACKGROUND Hepatobiliary manifestations occur in ulcerative colitis(UC)patients.The effect of laparoscopic restorative proctocolectomy(LRP)with ileal pouch anal anastomosis(IPAA)on hepatobiliary manifestations is debated.AIM To evaluate hepatobiliary changes after two-stages elective laparoscopic restorative proctocolectomy for patients with UC.METHODS Between June 2013 and June 2018,167 patients with hepatobiliary symptoms underwent two-stage elective LRP for UC in a prospective observational study.Patients with UC and having at least one hepatobiliary manifestation who underwent LRP with IPAA were included in the study.The patients were followed up for four years to assess the outcomes of hepatobiliary manifestations.RESULTS The patients'mean age was 36±8 years,and males predominated(67.1%).The most common hepatobiliary diagnostic method was liver biopsy(85.6%),followed by Magnetic resonance cholangiopancreatography(63.5%),Antineutrophil cytoplasmic antibodies(62.5%),abdominal ultrasonography(35.9%),and Endoscopic retrograde cholangiopancreatography(6%).The most common hepatobiliary symptom was Primary sclerosing cholangitis(PSC)(62.3%),followed by fatty liver(16.8%)and gallbladder stone(10.2%).66.4%of patients showed a stable course after surgery.Progressive or regressive courses occurred in 16.8%of each.Mortality was 6%,and recurrence or progression of symptoms required surgery for 15%.Most PSC patients(87.5%)had a stable course,and only 12.5%became worse.Two-thirds(64.3%)of fatty liver patients showed a regressive course,while one-third(35.7%)showed a stable course.Survival rates were 98.8%,97%,95.8%,and 94%at 12 mo,24 mo,36 mo,and at the end of the follow-up.CONCLUSION In patients with UC who had LRP,there is a positive impact on hepatobiliary disease.It caused an improvement in PSC and fatty liver disease.The most prevalent unchanged course was PSC,while the most common improvement was fatty liver disease. | Tamer A A M Habeeb Abdulzahra Hussain Mauro Podda Pasquale Cianci Bruce Ramshaw Khaled Safwat Wesam M Amr Tamer Wasefy Alaa A Fiad Mohamed Ibrahim Mansour Adel Mahmoud Moursi GamalOsman Anass Qasem Mohamed Fawzy Mohamed Ibrahim Abo Alsaad Abd-Elfattah Kalmoush MohammedShaaban Nassar Fawzy M Mustafa Mahmoud Hassib Morsi Badawy Ahmed Hamdy Hamdi Elbelkasi Bassam Mousa Abd-Elrahman M Metwalli Walid A Mawla Mostafa M Elaidy Muhammad Ali Baghdadi Ahmed Raafat | 2023 | World Journal of Gastrointestinal Surgery2023，15，2： | 0 |
| 3 | The Pyrenees as a cradle of plant diversity:phylogeny,phylogeography and niche modeling of Saxifraga longifolia显示文摘The current distribution of most species results from ecological niche,past distribution,and migrations during glacial–interglacial periods and in situ evolution.Here,we disentangle the colonization history of Saxifraga longifolia Lapeyr.,a limestone plant abundant in the Pyrenees and rare in other Iberian mountains and the African Atlas.Our working hypothesis is that the current distribution results from the shrinkage of a more extensive distribution in previous cold periods.We sampled 160 individuals of 32 populations across the whole distribution range and sequenced four DNA regions(rpl32-trnL,rps16-trnQ,trnS-trnG,and ITS).Ecological conditions were modeled to identify factors promoting high genetic diversity and long-term persistence areas for S.longifolia.In addition,we inferred phylogenetic relationships,phylogeographic divergence,genetic diversity,and migration routes.Seven plastid haplotypes were found,of which six occur in the Pyrenees and one in the High Atlas(Morocco).Discrete phylogeographic analysis(DPA)estimated migration routes predominantly from the Pyrenees to the other areas.Colonization events to those areas appear to have taken place recently given that the rest of the Iberian mountains do not harbor exclusive haplotypes.Iberian–Northern African distribution was inferred to be the result of long-distance dispersal because the split between Iberian and High Atlas haplotypes is estimated to have taken place in the last 4 million years ago when the Strait of Gibraltar was already open.Migrations from the Pyrenees to the south may have been favored by a corridor of predominant limestone rocks along Eastern Iberia,followed by successful overcoming the Strait of Gibraltar to reach northern Africa. | Fernando Pomeda-Gutiérrez María Begoña García María Leo Mario Fernández-Mazuecos Mostafa Lamrani Alaoui Anass Terrab Pablo Vargas | 2023 | Journal of Systematics and Evolution2023，61，2： | 0 |
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