|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Intraoperative cell salvage with autologous transfusion in liver transplantation显示文摘Liver transplant(LT) is the primary treatment for patients with end-stage liver disease. About 25000 LTs are performed annually in the world. The potential for intraoperative bleeding is quite variable. However, massive bleeding is common and requires blood transfusion. Allogeneic blood transfusion has an immunosuppressive effect and an impact on recipient survival, in addition to the risk of transmission of viral infections and transfusion errors, among others.Techniques to prevent excessive bleeding or to use autologous blood have been proposed to minimize the negative effects of allogeneic blood transfusion.Intraoperative reinfusion of autologous blood is possible through previous selfdonation or blood collected during the operation. However, LT does not normally allow autologous transfusion by prior self-donation. Hence, using autologous blood collected intraoperatively is the most feasible option. The use of intraoperative blood salvage autotransfusion(IBSA) minimizes the perioperative use of allogeneic blood, preventing negative transfusion effects without negatively impacting other clinical outcomes. The use of IBSA in patients with cancer is still a matter of debate due to the theoretical risk of reinfusion of tumor cells. However, studies have demonstrated the safety of IBSA in several surgical procedures, including LT for hepatocellular carcinoma. Considering the literature available to date, we can state that IBSA should be routinely used in LT, both in patients with cancer and in patients with benign diseases. | Marcelo A Pinto Marcio F Chedid Leo Sekine Andre P Schmidt Rodrigo P Capra Carolina Prediger Jo?o E Prediger Tomaz JM Grezzana-Filho Cleber RP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，1： | 16 |
| 2 | Systematic review: The placebo effect of psychological interventions in the treatment of irritable bowel syndrome显示文摘AIM To determine the placebo response rate associated with different types of placebo interventions used in psychological intervention studies for irritable bowel syndrome. METHODS Randomized controlled trials comparing psychological interventions(stress management/relaxation therapy(cognitive) behavioral therapy, short-term psychodynamic therapy, and hypnotherapy) for the treatment of adult patients with irritable bowel syndrome(IBS) diagnosed with the Manning or Rome criteria with an adequate placebo control treatment and reporting data on IBS symptom severity were identified by searching Pub Med, Embase, the Cochrane Library, CINAHL and Psyc INFO databases. Full-text articles that were written in English and published between 1966 and February 2016 in peer-reviewed journals were selected for the present review. Placebo interventions were considered to be adequate if the number of sessions and the amount of time spent with the therapist were the same as in the active treatment. The placebo response rate(PRR) was computed for IBS symptom severity(primary outcome measure) as well as for anxiety, depression and quality of life(secondary outcome measures). RESULTS Six studies, with a total of 555 patients met the inclusion criteria. Four studies used an educational intervention, whereas two studies used a form of supportive therapy as the placebo intervention. The PRR for IBS symptom severity ranged from 25% to 59%, with a pooled mean of 41.4%. The relative PRR for the secondary outcome measures ranged from 0% to 267% for anxiety, 6% to 52% for depression 20% to 125% for quality of life. The PRR associated with pharmacological treatments, treatment with dietary bran and complementary medicine ranged from 37.5% to 47%. Contrary to our expectations, the PRR in studies on psychological interventions was comparable to that in studies on pharmacological, dietary and alternative medical interventions.CONCLUSION The PRR is probably determined to a larger extent by patient-related factors, such as expectations and desire for the treatment to be effective, than the content of the placebo intervention. | Carla E Flik Laura Bakker Wijnand Laan Yanda R van Rood André JPM Smout Niek J de Wit | 2017 | World Journal of Gastroenterology2017，23，12： | 7 |
| 3 | Childhood Functional Gastrointestinal Disorders: Child/Adolescent显示文摘 | Andrée Rasquin Carlo Di Lorenzo David Forbes Ernesto Guiraldes Jeffrey S. Hyams Annamaria Staiano Lynn S. Walker | 2006 | Gastroenterology2006，，5： | 5 |
| 4 | 60d头低位卧床实验间中药对心血管控制的影响(英文)显示文摘目的本研究旨在通过头低位卧床60d试验,探讨中草药方剂太空养心丸(Tai Kong Yang Xin Prescription)对心血管自主神经功能控制及动脉压力反射功能的影响。方法14名健康志愿者,随机分为对照组(7名)和中草药治疗组(7名)。在卧床试验前、中、后,对志愿者的心血管变异性和动脉压力反射敏感度进行了详细评估。结果所有志愿者的心率都随卧床期的延长而逐步升高,并且在卧床后恢复期的第12天仍未恢复到卧床前的基础水平;平均动脉压也在卧床试验过程中逐渐升高,但在卧床结束后的第12天缓慢恢复到卧床前的水平;压力反射敏感度和呼吸性窦性心律不齐在卧床试验中明显下降,且在卧床结束后的恢复期仍保持很低水平;动脉收缩压的低频功率在卧床试验开始后升高,该值在整个卧床期及卧床后的恢复期均保持着较高的水平。虽然上述变化在对照组和中草药治疗组中没有显著性差异,并且两组的压力反射最佳延迟时间在卧床后均明显增加,但是在卧床期结束后的第12天,压力反射最佳延迟时间只在中草药治疗组中出现了部分的恢复。结论本研究首次探讨了太空养心丸对人体心脏自主神经功能影响的评价。研究结果表明该方剂对志愿者在模拟失重试验结束后的动脉压力反射最佳延迟时间的恢复有明显的帮助。 | 刘杰昕 李勇枝 Bart Verheyden 刘向昕 陈章煌 陈善广 谢琼 André E Aubert | 2009 | 航天医学与医学工程2009，22，6： | 4 |
| 5 | Numerical and safety considerations about the Daguangbao landslide induced by the 2008 Wenchuan earthquake显示文摘The 2008 Wenchuan earthquake resulted in a large number of fatalities and caused significant economic losses.Thousands of landslides,many of which are very large,were triggered by the earthquake.A majority of catastrophic landslides were distributed along the central Longmenshan fault system,at the eastern margin of the Tibetan Plateau.Some of the landslides resulted in sudden damming of rivers causing flooding,which in turn induced secondary sliding disasters.Among the most significant landslides,the Daguangbao landslide was the largest in volume with the maximum thickness.For this,a numerical model of the Daguangbao landslide,using the material point method(MPM),was developed to simulate the interaction of the seismic loads imposed on the slope.The numerical results then are compared with the post-earthquake profile.As a consequence of the landslide,a nearly vertical head scarp with a maximum height of about 700 m was generated.This is considered as a high risk situation that requires constant monitoring and evaluation.Finally,we propose a methodology based on Bayesian networks(BNs)to manage the risk associated with the stability of the rockwall at the Daguangbao landslide site. | Manchao He L.Ribeiro e Sousa AndréMüller Eurípedes Vargas Jr. R.L.Sousa C.Sousa Oliveira Weili Gong | 2019 | Journal of Rock Mechanics and Geotechnical Engineering2019，11，5： | 4 |
| 6 | Pancreaticβ-cell dysfunction in type 2 diabetes:Implications of inflammation and oxidative stress显示文摘Insulin resistance and pancreaticβ-cell dysfunction are major pathological mechanisms implicated in the development and progression of type 2 diabetes(T2D).Beyond the detrimental effects of insulin resistance,inflammation and oxidative stress have emerged as critical features of T2D that defineβ-cell dysfunction.Predominant markers of inflammation such as C-reactive protein,tumor necrosis factor alpha,and interleukin-1βare consistently associated withβ-cell failure in preclinical models and in people with T2D.Similarly,important markers of oxidative stress,such as increased reactive oxygen species and depleted intracellular antioxidants,are consistent with pancreaticβ-cell damage in conditions of T2D.Such effects illustrate a pathological relationship between an abnormal inflammatory response and generation of oxidative stress during the progression of T2D.The current review explores preclinical and clinical research on the pathological implications of inflammation and oxidative stress during the development ofβ-cell dysfunction in T2D.Moreover,important molecular mechanisms and relevant biomarkers involved in this process are discussed to divulge a pathological link between inflammation and oxidative stress duringβ-cell failure in T2D.Underpinning the clinical relevance of the review,a systematic analysis of evidence from randomized controlled trials is covered,on the potential therapeutic effects of some commonly used antidiabetic agents in modulating inflammatory makers to improveβ-cell function. | Phiwayinkosi V Dludla Sihle E Mabhida Khanyisani Ziqubu Bongani B Nkambule Sithandiwe E Mazibuko-Mbeje Sidney Hanser Albert Kotze Basson Carmen Pheiffer Andre Pascal Kengne | 2023 | World Journal of Diabetes2023，14，3： | 2 |
| 7 | A New Technique to Perform Epicardial Mapping in the Electrophysiology Laboratory显示文摘 | EDUARDOSOSA MAURICIOSCANAVACCA ANDRéD'AVILA EúLVIOPILLEGGI | 2007 | Journal of Cardiovascular Electrophysiology2007，，6： | 2 |
| 8 | Novel pharmacological therapy in type 2 diabetes mellitus with established cardiovascular disease: Current evidence显示文摘Cardiovascular diseases(CVDs) remain the leading cause of death in the world and in most developed countries. Patients with type 2 diabetes mellitus(T2DM)suffer from both microvascular and macrovascular diseases and therefore have higher rates of morbidity and mortality compared to those without T2DM. If current trends continue, the Center for Disease Control and Prevention estimates that 1 in 3 Americans will have T2DM by year 2050. As a consequence of the controversy surrounding rosiglitazone and the increasing prevalence of diabetes and CVDs, in 2008 the Food and Drug Administration(FDA) established new expectations for the evaluation of new antidiabetic agents, advising for pre and,in some cases, post-marketing data on major cardiovascular events. As a direct consequence, there has been a paradigm shift in new antidiabetic agents that has given birth to the recently published American Diabetes Association/European Association for the Study of Diabetes consensus statement recommending sodium-glucose cotransporter-2 inhibitors(SGLT2i) and glucagon like peptide-1 receptor agonists(GLP-1RA) in patients with T2DM and established CVD. As a result of over a decade of randomized placebo controlled cardiovascular outcome trials, the aforementioned drugs have received FDA approval for risk reduction of cardiovascular(CV) events in patients with T2DM and established CV disease.SGLT2i have been shown to have a stronger benefit in patients with congestiveheart failure and diabetic kidney disease when compared to their GLP-1RA counterparts. These benefits are not withstanding additional considerations such as cost and the multiple FDA Black Box warnings. This topic is currently an emerging research area and this mini-review paper examines the role of these two novel classes of drugs in patients with T2DM with both confirmed, and at risk for, CVD. | Leonardo Pozo Fatimah Bello Andres Suarez Francisco E Ochoa-Martinez Yamely Mendez Chelsea H Chang Salim Surani | 2019 | World Journal of Diabetes2019，10，5： | 2 |
| 9 | Mammalian defensins in the antimicrobial immune response显示文摘 | Michael E S Andre J O | 2005 | Nature Reviews Immunology2005，6，6： | 1 |
| 10 | Update of nutrient-deficiency ane- mia in elderly patients 显示文摘 | Andres E Federici L Serraj K | 2008 | Eur J Intern Med2008，19，7： | 1 |
| 11 | Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents显示文摘 | Andre E Campi B Materazzi S | 2008 | J Clin Invest2008，118，7： | 1 |
| 12 | Postexposure application of Fas receptor small-interfering RNA to suppress sulfur mustard-induced apoptosis in human airway epithelial cells:implication for a therapeutic approach显示文摘 | Keyser BM Andres DK Nealley E Holmes WW Benton B Paradiso D | 2013 | J Pharmacol Exp Ther2013，344，1： | 1 |
| 13 | An Introduction to Variable and Feature Selection显示文摘 | lsabelle G Andre E | 2003 | Journal of Machine Learning Research2003，，3： | 1 |
| 14 | Validation of the Pediatric Rome II Criteria for Functional Gastrointestinal Disorders Using the Questionnaire on Pediatric Gastrointestinal Symptoms显示文摘 | Arlene Caplan Lynn Walker Andrée Rasquin | 2005 | Journal of Pediatric Gastroenterology and Nutrition2005，，3： | 1 |
| 15 | Transcription of the gene coding for subunit 9 of ATP synthase in rice mitochondria 显示文摘 | Kaleikau E K Andre C P Walbot V | 1993 | Plant Mol Biol1993，22，： | 1 |
| 16 | Procalcitonin and C-reactive protein as markers of systemic inflammatory response syndrome severity in critically ill children 显示文摘 | Corsino Rey Marta Los Arcos Andr e s Concha | 2007 | Intensive Care Med2007，33，3： | 1 |
| 17 | Polygodial-induced noradrenaline release in human neuroblastoma SH-SYSY cells 显示文摘 | Andres M I Forsby A Walum E | 1997 | Toxicology in Vitro1997，11，： | 1 |
| 18 | Characterization of gold-titania catalysts via oxidation of propylene to propyleneoxide 显示文摘 | Stangland E E Stavens K B Andres R P etal | 2000 | Journal of Catalysis2000，191，： | 1 |
| 19 | Reconstitution of lethal y irradiated mice by cel s isolated from adipose tissue显示文摘 | Cousin B André M Arnaud E | | 0，，04： | 1 |
| 20 | Acetaminophen, via its reac- tive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflam- mation in the airways and other tissues in rodents显示文摘 | Nassini R Materazzi S Andre E | 2010 | FASEB J2010，24，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员