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| 1 | The influence of transforming growth factor‐α, cyclooxygenase‐2, matrix metalloproteinase (MMP)‐7, MMP‐9 and CXCR4 proteins involved in epithelial–mesenchymal transition on overall survival of patients with gastric cancer显示文摘 | Marcello Ferretti Fanelli Ludmilla T Domingos Chinen Maria Dirlei Begnami Wilson Luis Costa José Humberto T Fregnami Fernando A Soares André Luis Montagnini | 2012 | Histopathology2012，，2： | 2 |
| 2 | Therapeutic drug monitoring in patients with inflammatory bowel disease显示文摘Thiopurine analogs and anti-tumor necrosis factor(TNF)agents have dramatically changed the therapeutics of inflammatory bowel diseases(IBD),improving short and long-term outcomes.Unfortunately some patients do not respond to therapy and others lose response over time.The pharmacokinetic properties of these drugs are complex,with high inter-patient variability.Thiopurine analogs are metabolized through a series of pathways,which vary according to the patients’pharmacogenetic profile.This profile largely determines the ratios of metabolites,which are in turn associated with likelihoods of clinical efficacy and/or toxicity.Understanding these mechanisms allows for manipulation of drug dose,aiming to reduce the development of toxicity while improving the efficacy of treatment.The efficacy of anti-TNF drugs is influenced by many pharmacodynamic variables.Several factors may alter drug clearance,including the concomitant use of immunomodulators(thiopurine analogs and methotrexate),systemic inflammation,the presence of anti-drug antibodies,and body mass.The treatment of IBD has evolved with the understanding of the pharmacologic profiles of immunomodulating and TNF-inhibiting medications,with good evidence for improvement in patient outcomesobserved when measuring metabolic pathway indices.The role of routine measurement of metabolite/drug levels and antibodies warrants further prospective studies as we enter the era of personalized IBD care. | Andres J Yarur Maria T Abreu Amar R Deshpande David H Kerman Daniel A Sussman | 2014 | World Journal of Gastroenterology2014，20，13： | 2 |
| 3 | A review of GEBCOD trial of bimonthly leucovorin plus 5-fluorouracil 48h continuous infusion in advanced colorectal cancer: evolutions ofa regimen 显示文摘 | De Gramont A Louvet C Andre T | 1998 | Eur J Cancer1998，34，5： | 1 |
| 4 | Guardian maps and the generalized stability of parametrized families of matrices and polynomials显示文摘 | Saydy L Andre L T Eyad H A | 1990 | Mathe- matics of Control Signals and Systems1990，3，4： | 1 |
| 5 | Metal mesh foil bearing: Effect of motion amplitude, rotor speed, static load, and excita- tion frequency on force coefficients 显示文摘 | ANDRES L S CHIRATHADAM T A | 2011 | Journal of Engineering for Gas Turbines and Power2011，133，12： | 1 |
| 6 | Adjuvant treatment of colon cancer MOSAIC study's main results显示文摘 | De Gramont A Andre T Tournigand C | 2006 | Bull Cancer2006，93，1： | 1 |
| 7 | Liquid phase hydrogenation of cinnamaldehyde on Cu-based catalysts 显示文摘 | Alberto J M Diego A G Andres F T | 2003 | Applied Catalysis A : General2003，249，： | 1 |
| 8 | Streams, Structures, Spaces, Scenarios, Societies (5S) :A Formal Model for Digial Libraries显示文摘 | Edward A Fox Layne T Watson | 2004 | ACM Transactions on Information Systems2004，22，2： | 1 |
| 9 | Molecular phenotype of zebrafish ovarian follicle by serial analysis of gene expression and proteomic profiling, and comparison with the transcriptomes of other animals 显示文摘 | Knoll-Gellida A Andre M Gattegno T | 2006 | BMC Genomies2006，7，： | 1 |
| 10 | Molecular phenotype of zebrafish ovarian follicle by serial analysis of gene expression and proteomie prof'ding, and comparison with the transcfiptomes of other animals 显示文摘 | KNOLL-GELLIDA A ANDRE M GATYEGNO T | 2006 | BMC Genomics2006，7，： | 1 |
| 11 | Nanostructure of nafion membrane at different states of hydration: an IR and Raman study显示文摘 | Gruger A André Régis Schmatko T | 2001 | Vibrational Spectroscopy2001，26，： | 1 |
| 12 | OPTIMOX study:FOLFOX 7/LV5FU2 compared to FOLFOX 4 in patients with advanced colorectal cancer显示文摘 | De Gramont A Cervantes A Andre T | 2004 | J Clin Oncol2004，22，35： | 1 |
| 13 | Effects of hydrogen peroxide and nitric oxide on both salt and heat stress tolerance in rice显示文摘 | UCHIDA A ANDRE T J TAKASHI H | 2002 | Plant Science2002，163，： | 1 |
| 14 | Similarities and differences between the adjuvant oxaliplatin-based trials MOSAIC and NSABP C-07 显示文摘 | De Gramont A Boni C Andre T | 2009 | Current Colorectal Cancer Reports2009，5，3： | 1 |
| 15 | Effects of hydrogen peroxide and nitricoxideon both salt and heat stress tolerance in rice显示文摘 | Uchida A Andre T I Takashi H | | 0，，： | 1 |
| 16 | Pesticide Residues and Vertical Integration in Florida Strawberries and Tomatoes显示文摘 | Kilmer R Andre A Stevens T | | 0，，17： | 1 |
| 17 | Forecasting models for interval-valued time series 显示文摘 | Andre Luis S Maia Francisco de A T de Carvalho Teresa B Ludermir | 2008 | Neurocomputing2008，71，： | 1 |
| 18 | Effect of salt stress on antioxidative enzymes and lipid peroxidation in leaves and roots of salt-tolerant and salt-sensitive maize genotypes显示文摘 | ANDR(E) A D N A JOS(E)T P JOAOUIM E F | 2006 | Environmental and Experimental Botany2006，56，： | 1 |
| 19 | Gadolinium free cardiovascular magnetic resonance with 2-point Cine balanced steady state free precession显示文摘 | Stromp T A Leung S W Andres K N | 2015 | Journal of Cardiovascular Magnetic Resonance2015，17，1： | 1 |
| 20 | Synthesis and Characterization of Star Polymers Made from Simple, Multifunctional Initiators 显示文摘 | D R Robello A Andre T A McCovick | 2002 | Macromolecules2002，35，25： | 1 |
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