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1篇 您的检索式：作者名="Andri Cherninskyi"

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		题名	作者	年代	出处	被引量
	1	Triggering of Major Brain Disorders by Protons and ATP:The Role of ASICs and P2X Receptors显示文摘Adenosine triphosphate(ATP)is well-known as a universal source of energy in living cells.Less known is that this molecule has a variety of important signaling func-tions:it activates a variety of specific metabotropic(P2Y)and ionotropic(P2X)receptors in neuronal and non-neu-ronal cell membranes.So,a wide variety of signaling func-tions well fits the ubiquitous presence of ATP in the tissues.Even more ubiquitous are protons.Apart from the unspe-cific interaction of protons with any protein,many physi-ological processes are affected by protons acting on specific ionotropic receptors--acid-sensing ion channels(ASICs).Both protons(acidification)and ATP are locally elevated in various pathological states.Using these fundamentally important molecules as agonists,ASICs and P2X receptors signal a variety of major brain pathologies.Here we briefly outline the physiological roles of ASICs and P2X receptors,focusing on the brain pathologies involving these receptors.	Andri Cherninskyi Maksim Storozhuk Oleksandr Maximyuk Vyacheslav Kulyk Oleg Krishtal	2023	Neuroscience Bulletin2023，39，5：	0

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