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| 1 | Use of Sorghum Crops for in Situ Phytoremediation of Polluted Soils显示文摘 | V. R. Angelova R. V. Ivanova V. A. Delibaltova K. I. Ivanov | 2011 | Journal of Agricultural Science and Technology(A)2011，1，5： | 10 |
| 2 | Interleukin-6 compared to the other Th17/Treg related cytokines in inflammatory bowel disease and colorectal cancer显示文摘BACKGROUND The connection between inflammatory bowel disease(IBD)and colorectal cancer(CRC)is well-established,as persistent intestinal inflammation plays a substantial role in both disorders.Cytokines may further influence the inflammation and the carcinogenesis process.AIM To compare cytokine patterns of active IBD patients with early and advanced CRC.METHODS Choosing a panel of cytokines crucial for Th17/Treg differentiation and behavior,in colon specimens,as mRNA biomarkers,and their serum protein levels.RESULTS We found a significant difference between higher gene expression of FoxP3,TGFb1,IL-10,and IL-23,and approximately equal level of IL-6 in CRC patients in comparison with IBD patients.After stratification of CRC patients,we found a significant difference in FoxP3,IL-10,IL-23,and IL-17A mRNA in early cases compared to IBD,and IL-23 alone in advanced CRC.The protein levels of the cytokines were significantly higher in CRC patients compared to IBD patients.CONCLUSION Our findings showed that IL-6 upregulation is essential for both IBD and CRC development until the upregulation of other Th17/Treg related genes(TGFb1,IL-10,IL-23,and transcription factor FoxP3)is a crucial primarily for CRC development.The significantly upregulated IL-6 could be a potential drug target for IBD and prevention of CRC development as well. | Tsvetelina Veselinova Velikova Lyuba Miteva Noyko Stanilov Zoya Spassova Spaska Angelova Stanilova | 2020 | World Journal of Gastroenterology2020，26，16： | 10 |
| 3 | 英语口语语法在教学中的适应性分析显示文摘本文分析了口语语法作为应用语法与核心语法具有统一性,应该强调语域意识在口语教学中的重要性,口语教学应重视会话语法与语言功能,应该针对口语语言的不同特点,如省略、词语脱位、递加结构等,采用不同的教学策略。 | 李凤华 Maria Angelova | 2010 | 山东外语教学2010，，4： | 9 |
| 4 | Regulation of the New Arabidopsis Imprinted Gene AtBMI1C Requires the Interplay of Different Epigenetic Mechanisms显示文摘最近,植物包含相当或相同的事物到动物 Polycomb 压抑的建筑群,这被显示出 1 (PRC1 ) 部件 BMI1 和 RING1A/B。在 Arabidopsis,有三象 BMI1 一样基因,哪个中的二个, AtBMI1A 和 B,在 embryonic 以后植物生长期间被要求镇压胚胎的特点并且允许房间区别。然而,很少对第三象 BMI1 一样基因被知道, AtBMI1C。在这个工作,我们证明 AtBMI1C 仅仅在内乳和雄蕊开发期间被表示。AtBMI1C 是在内乳从母亲的等位基因表示,但是 biallelically 在雄蕊表示了的印的基因。我们发现 AtBMI1C 的典型表示模式是包含 CG DNA methylation,指导 RNA 的 non-CG DNA methylation (RdDM ) ,和 PcG 活动的一条复杂 epigenetic 规定的结果。我们的结果在在整个开发调整基因表示显示出不同 epigenetic 机制的安排相互影响,使为在工厂内乳印的起源和机制的当前的假设清楚些。 | Fabian Bratzel ChaoYang Alexandra Angelova Gema Lopez-Torrejon Marcus Koch Juan Carlos del Pozo Myriam Calonje | 2012 | Molecular Plant2012，5，1： | 4 |
| 5 | Optimization problems for one-impulsive models from population dynamics显示文摘 | J. Angelova A. Dishliev | 2000 | Nonlinear Analysis2000，，4： | 3 |
| 6 | Dual and multi-drug delivery nanoparticles towards neuronal survival and synaptic repair显示文摘Among the macromolecular drug targets in neurodegenerative disorders, the neurotrophin brain-derived neurotrophic factor(BDNF) and its high-affinity tropomyosin-related kinase receptor(Trk B) present strong interest for nanomedicine development aiming at neuronal and synaptic repair. Currently, BDNF is regarded as the neurotrophic factor of highest therapeutic significance. However, BDNF has delivery problems as a protein drug. The enhanced activation of the transcription factor CREB(c AMP response element-binding protein) has been evidenced to increase the BDNF gene expression and hence the production of endogenous BDNF. We assume that BDNF delivery by nanocarriers and mitochondrial protection may provide high potential for therapeutic amelioration of the neuroregenerative strategies. Beneficial therapeutic outcomes may be expected for synergistic dual or multi-drug action aiming at(i) neurotrophic protein regulation in the central and peripheral nervous systems, and(ii) diminishment of the production of reactive oxygen species(ROS) and the oxidative damage in mitochondria. Our research strategy is based on a nanoarchitectonics approach for the design of nanomedicine assemblies by hierarchical self-assembly. We explore nanoarchitectonics concepts in soft-matter nanotechnology towards preparation of biodegradable self-assembled lipid nanostructures for safe neuro-therapeutic applications of multi-target nanomedicines. | Angelina Angelova Borislav Angelov | 2017 | Neural Regeneration Research2017，12，6： | 3 |
| 7 | The effect of flutamide on the physical working capacity and activity of some of the key enzymes for the energy supply in adult rats显示文摘学习的目的是在老鼠为精力供应在一些关键肌肉酶的物理工作能力和活动上估计雄激素受体对手的效果。年轻成年男 Wistar 老鼠被划分成二个组。一个组一个星期和作为控制为服务 8 个星期的另外的组每天收到了 flutamide 的 15 mg kg-1 6 天。在开始并且在实验的结束,所有老鼠受到 submaximal 跑耐力(SRE ) ,疲劳(MTE ) 的最大的时间,和最大的疾跑速度(女士) 测试。在试用的结束,最大的氧消费(VO2max ) 测试被执行并且睾丸激素,红血球,血红素以及 succinate 脱氢酶(同步数字系列) 的酶活动的层次,喂奶脱氢酶(LDH ) ,和 gastrocnemius 肌肉的 NAD.H2-cytochrome-c reductase (NAD.H2 ) 被测量。对待 flutamide 的老鼠的浆液睾丸激素比控制的高,它验证选择的剂量的有效性。anti-androgen-treated 组的 MTE 和 SRE 与起始的价值相比是更低的。Flutamide 处理减少了同步数字系列和 NAD.H2 的活动与控制相比。我们没在女士, VO2max,跑的经济, LDH 活动,和 hematological 变量上发现反雄激素处理的效果。我们的调查结果显示象一些关键酶的活动一样的 submaximal 和最大的跑耐力的维护把氧化能力与肌肉联系了与雄激素效果被连接由雄激素受体调停了。 | Katerina N Georgieva Penka A Angelova Fani D Gerginska Dora D Terzieva Mihaela S Shishmanova-Doseva Slavi D Delchev Valentine V Vasilev | 2017 | Asian Journal of Andrology2017，19，4： | 2 |
| 8 | 电场或电磁场和光动力的协同效应对癌细胞失活和坏死的作用(英文)显示文摘 应用弱正弦波电磁场改变细胞膜的穿透性并引起其失活和坏死.研究中,将人类癌细胞U 937和K 562放置于强度为10mT和39mT(50Hz)的正弦波电磁场内,并依次结合细胞毒素放线菌素 C以及其独特的光动力活性分别进行试验. | Maria Radeva Maya Lambrera Plamena Angelova Nelly Traitcheva Hermann Berg | 2004 | 电化学2004，10，3： | 2 |
| 9 | Structure-function relationships of the luteinizing hormone receptor显示文摘 | Puett D Li Y Angelova K | 2005 | Ann N Y Acad Sci2005，1061，2： | 1 |
| 10 | Alterations in p53, BRCA1, ATM, PIK3CA, and HER2 genes and their effect in modifying clinicopathological characteristics and overall survival of Bulgarian patients with breast cancer 显示文摘 | Bozhanov SS Angelova SG Krasteva ME | 2010 | J Cancer IRes Clin Oncol2010，136，11： | 1 |
| 11 | Polycrystalline Silicon Thin Films Obtained by Ni-induced Crystallization on Glass Substrate显示文摘 | Dimova-malinovskaa D Angelova O Sendova-vassilevaa M | 2004 | Vacuum2004，76，： | 1 |
| 12 | Design and comparison of mode-set adaptive IMM algorithms for maneuvering target tracking显示文摘 | JILKOV V P ANGELOVA D S SEMERDJIEV T A | | 0，，01： | 1 |
| 13 | Interaction of neurons and astrocytesunderlies the mechanism of Ap-induced neurotoxicity 显示文摘 | Angelova PR Abramov AY | 2014 | Biochem SocTrans2014，42，5： | 1 |
| 14 | Bio - accumulation and distribution of heavy metals in fibre crops (flax, cotton and hemp) 显示文摘 | Angelova V Ivanova R Ddlibahova V | 2004 | In- dustrial Crops and Products2004，19，： | 1 |
| 15 | Bio-accumulation and distribution of heavy metals in fiber crops(flax,cotton and hemp)显示文摘 | ANGELOVA V IVANOVA R DELIBALTOVA V | 2004 | Ind Crops Prod2004，19，： | 1 |
| 16 | Design and comparison of mode-set adaptive IMM algorithms for maneuvering target tracking显示文摘 | Jilkov V P Angelova D S Semerdjiev T A | 1999 | IEEE Trans on Aerospace and Electronic Systems1999，35，1： | 1 |
| 17 | A note on modelling short fatigue crack behaviour显示文摘 | Akid R | 1998 | Fatigue Fract Engng Mater Struct1998，21，1： | 1 |
| 18 | Bio-accumulation and distribution of heavy metals in fibre crops( flax, cotton and hemp) 显示文摘 | Angelova V Ivanova R Delibaltova V | 2004 | Industrial Crops and Products2004，19，： | 1 |
| 19 | Bio-accumulation and distribution of heavy met- als in black mustard (Brassiea nigra Koch) 显示文摘 | Angelova V Ivanov K | 2009 | Environ Monit Assess2009，，153： | 1 |
| 20 | Design and comparison of model-set adaptive IMM algorithms for maneuvering target tracking显示文摘 | V P Jilkov D S Angelova TZ A Semerdjiev | 1999 | IEEE Trans AES1999，35，1： | 1 |
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