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| 1 | Role of live microbial feed supplements with reference to anaerobic fungi in ruminant productivity: A review显示文摘To keep the concept of a safe food supply to the consumers, animal feed industries world over are showing an increasing interest in the direct-fed microbials(DFM) for improved animal performance in terms of growth or productivity. This becomes all the more essential in a situation, where a number of the residues of antibiotics and/or other growth stimulants reach in milk and meat with a number of associated potential risks for the consumers. Hence, in the absence of growth stimulants, a positive manipulation of the rumen microbial ecosystem to enhance the feedstuff utilization for improved production efficiency by ruminants has become of much interest to the researchers and entrepreneurs. A few genera of live microbes(i.e., bacteria, fungi and yeasts in different types of formulations from paste to powder) are infrequently used as DFM for the domestic ruminants. These DFM products are live microbial feed supplements containing naturally occurring microbes in the rumen. Among different DFM possibilities, anaerobic rumen fungi(ARF) based additives have been found to improve ruminant productivity consistently during feeding trials. Administration of ARF during the few trials conducted, led to the increased weight gain, milk production, and total tract digestibility of feed components in ruminants. Anaerobic fungi in the rumen display very strong cell-wall degrading cellulolytic and xylanolytic activities through rhizoid development, resulting in the physical disruption of feed structure paving the way for bacterial action. Significant improvements in the fiber digestibility were found to coincide with increases in ARF in the rumen indicating their role. Most of the researches based on DFM have indicated a positive response in nutrient digestion and methane reducing potential during in vivo and/or in vitro supplementation of ARF as DFM. Therefore, DFM especially ARF will gain popularity but it is necessary that all the strains are thoroughly studied for their beneficial properties to have a confirmed ‘generally regarded as safe' status for ruminants. | Anil K Puniya Abdelfattah Z M Salem Sanjay Kumar Sumit S Dagar Gareth W Griffith Monica Puniya Sreenivas R Ravella Nikhil Kumar Tejpal Dhewa Ravinder Kumar | 2015 | Journal of Integrative Agriculture2015，14，3： | 17 |
| 2 | Staining for p53 and Ki-67 increases the sensitivity of EUS-FNA to detect pancreatic malignancy显示文摘AIM:To investigate whether tumor marker staining can improve the sensitivity of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)to diagnose pancreatic malignancy. METHODS:Patients who underwent EUS-FNA were retrospectively identified.Each EUS-FNA specimen was evaluated by routine cytology and stained for tumor markers p53,Ki-67,carcinoembryonic antigen(CEA) and CA19-9.Sensitivity,specificity,positive and negative predictive values(PPV and NPV),and positive and negative likelihood ratios(PLR and NLR)were calculated in order to evaluate the performance of each test to detect malignancy. RESULTS:Sixty-one specimens had complete sets of stains,yielding 49 and 12 specimens from pancreatic adenocarcinomas and benign pancreatic lesions due to pancreatitis,respectively.Cytology alone had sensitivity and specificity of 41%and 100%to detect malignancy, respectively.In 46%of the specimens,routine cytology alone was deemed indeterminate.The addition of either p53 or Ki-67 increased the sensitivity to 51%and 53%,respectively,with perfect specificity,PPV and PLR (100%,100%and infinite).Both stains in combination increased the sensitivity to 57%.While additional staining with CEA and CA19-9 further increased the sensitivity to 86%,the specificity,PPV and PLR were significantly reduced(at minimum 42%,84%and 1,respectively).Markers in all combinations performed poorly as a negative test(NPV 26%to 47%,and NLR 0.27 and 0.70).CONCLUSION:Immunohistochemical staining for p53 and Ki-67 can improve the sensitivity of EUS-FNA to diagnose pancreatic adenocarcinoma. | Alexander W Jahng Sonya Reicher David Chung Donna Varela Rahul Chhablani Anil Dev Binh Pham Jose Nieto Rose J Venegas Samuel W French Bruce E Stabile Viktor E Eysselein | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，11： | 3 |
| 3 | Tumor targeted mesoporous silica-coated gold nanorods facilitate detection of pancreatic tumors using Multispectral optoacoustic tomography显示文摘Multispectral optoacoustic 断层摄影术(MSOT ) 是在传统的形式上提供几个优点的一种新兴的成像技术,特别地处于它解决在显微镜的规模上的深度的光对比的能力。当潜在的应用包括临床的阀值由当前的技术设置了的下面的肿瘤的早察觉时,肿瘤特定的对比代理人的缺乏限制 MSOT 成像的使用。因此,我们与 polyacrylic 酸(泛美航空公司) 或 aminefunctionalized mesoporous 硅石(MS ) 由涂层金牌 nanorods (GNR ) 构造了高度稳定的 nano 对比代理人。Syndecan-1,被显示了指向像胰岛素的生长因素 1 受体(IGF1-R )( 在胰腺的肿瘤的 upregulated ) ,在泛美航空公司涂的 GNR (PAA-GNRs ) 或 MS 涂的 GNR (MS-GNRs ) 的表面上被结合创造指向肿瘤的 nanoparticles。在 vitro, nanoparticles 指向的肿瘤与流动 cytometry 被估计。在 S2VP10L 房间(为 IGF1-R 积极) , syndecan-1 MS-GNRs (Syndecan-MS-GNRs ) 在 OA 信号表明了增加, 10x,与 syndecan-1 PAAGNR (Syndecan-PAA-GNRs ) 相比。最小的绑定在 MiaPaca-2 房间被观察(为 IGF1-R 否定) 。在 vivo,肿瘤 Syndecan-MS-GNRs 的特定的指向用鼠科的 orthotopic 被评估胰腺的癌症模型。Syndecan- MS-GNRs 比在象肝那样的离开目标机关在胰腺的肿瘤以内表明了显著地更大的累积。与 IGF1-R 否定 MiaPaca-2 房间植入的老鼠没表明指向的特定的肿瘤。在摘要,我们报导指向的 nano 对比代理人(Syndecan-MS-GNRs ) 能成功地检测 orthotopic 有在用 MSOT 的 vivo 有约束力的最小的离开目标的胰腺的肿瘤。 | Anil Khanal Christopher Ullum Charles W Kimbrough Nichola C. Garbett Joseph A. Burlison Molly W. McNally Phillip Chuong Ayman S. EI-Baz Jacek B. Jasinski Lacey R. McNally | 2015 | Nano Research2015，8，12： | 2 |
| 4 | A novel approach to bulk synthesis of carbon nanotubes filled whti metal by a catalytic chemical vapor deposition method显示文摘 | Sinha Anil K Hwang Dennis W Hwang Lianpin | 2000 | Chem Plays Lett2000，332，56： | 1 |
| 5 | Structural and functional organization of the animal fatty acid synthase显示文摘 | STUART S ANDRZEJ W ANIL K J | 2003 | Prog Lipid Res2003，40，： | 1 |
| 6 | Statistical pattern recognition:a review显示文摘 | Anil K Jain Robert P W Duin Mao Jianchang | 2000 | IEEE Trans2000，22，1： | 1 |
| 7 | Statistical pattern recognition: A review显示文摘 | Anil K Jain Robert P W Duin Mao Jianchang | 2000 | IEEE Trans on Pattern Analysis and Machine Intelligence2000，22，1： | 1 |
| 8 | Structural and functionalorgani- zation of the animalfatty acid synthase 显示文摘 | Stuart S Andrzej W Anil KJ | 2003 | Prog Lipid Res2003，40，： | 1 |
| 9 | Conducting and Integrating Strategy Research at the International,Corporate,and BusinessLevels: Issues and Directions 显示文摘 | Dess Gregory G Anil Gupta Jean-Francois Hennart and Charles W L Hill | 1995 | Journal of Management1995，21，： | 1 |
| 10 | Instability of BaCeO3 in H2O-containing Atmospheres显示文摘 | Cameron W T Anil V V | 1996 | J Electrochem Soc1996，143，4： | 1 |
| 11 | HZSM-5 catalyzed cyclodehydration of diethylene glycol and its derivatives 显示文摘 | Anil W Muthukumaru P S Unnikrishnan S | 1996 | J Mol Catal A: Chemical1996，109，2： | 1 |
| 12 | Responses in the voluntary intake of hay or silage by lactating cows to intra- ruminal infusions of sodium acetate or sodium propionate, the tonicity of rumen fluid or rumen distension显示文摘 | Anil M H Mbanya J N Symonds H W | 1993 | British Journal of Nutrition1993，69，： | 1 |
| 13 | Current aspects in pharmacology of modified hemoglobins显示文摘 | Rameshraja P Huashan W Anil G | 2000 | Adv Drug Deliv Review2000，40，： | 1 |
| 14 | Serum leptin levels in children and adolescents with insulin dependent diabetes mellitus in relative to metabolitic control and body mass index显示文摘 | Kiess W Anil M Blum WF | 1998 | Eur J Endocrinal1998，138，5： | 1 |
| 15 | Deregu-lation, Disintermediation and Agency Costs of Debt:Eevi-dence From Japan显示文摘 | Christopher W Anderson Anil K.Makhija | | 0，，02： | 1 |
| 16 | Statistical pattern recognition:a view显示文摘 | FELLOW J ROBERT P W | 2000 | IEEE Transactions on pattern analysis and machine intelligence2000，22，2： | 1 |
| 17 | Statistical Pattern Recognition: A Review显示文摘 | Anil K Jain Robert P W Duin and Jianchang Mao | 2000 | IEEE Transaction on Pattern Analysis and Machine Intelligence2000，22，1： | 1 |
| 18 | Board Composition and Corporate Control: Evidence from the Insurance Industry 显示文摘 | Mayers David & Shivdasani Anil & Smith Clifford W Jr | 1997 | Journal of Business University of Chicago Press1997，70，1： | 1 |
| 19 | Direct trajectory optimization using a variable low-order adaptive pseudospectral method 显示文摘 | CHRISTOPHER L D W LLLAM W H ANIL V R | 2011 | Journal of Spacecraft and Rockets2011，48，3： | 1 |
| 20 | An hp-adaptive pseudospectral method for solving optimal control problems显示文摘 | DARBY C L HAGER W W ANIL V R | 2011 | Optimal Control Applications and Methods2011，32，4： | 1 |
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