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| 1 | Beta-blocker therapy in elderly patients with renal dysfunction and heart failure显示文摘OBJECTIVE To assess the role of beta-blockers(BB)in patients with chronic kidney disease(CKD)aged≥75 years.METHODS AND RESULTS From January 2008 to July 2014,we included 390 consecutive patients≥75 years of age with ejection fraction≤35%and glomerular filtration rate(GFR)≤60 m L/min per 1.73 m^2.We analyzed the relationship between treatment with BB and mortality or cardiovascular events.The mean age of our population was 82.6±4.1 years.Mean ejection fraction was 27.9%±6.5%.GFR was 60-45 m L/min per 1.73 m^2 in 50.3%of patients,45-30 m L/min per 1.73 m^2 in 37.4%,and<30 m L/min per 1.73 m^2 in 12.3%.At the conclusion of follow-up,67.4%of patients were receiving BB.The median follow-up was28.04(IR:19.41-36.67)months.During the study period,211 patients(54.1%)died and 257(65.9%)had a major cardiovascular event(death or hospitalization for heart failure).BB use was significantly associated with a reduced risk of death(HR=0.51,95%CI:0.35-0.74;P<0.001).Patients receiving BB consistently showed a reduced risk of death across the different stages of CKD:stage IIIa(GFR=30-45 m L/min per 1.73 m^2;HR=0.47,95%CI:0.26-0.86,P<0.0001),stage IIIb(GFR 30-45 m L/min per 1.73 m^2;HR=0.55,95%CI:0.26-1.06,P=0.007),and stages IV and V(GFR<30 m L/min per 1.73 m~2;HR=0.29,95%CI:0.11-0.76;P=0.047).CONCLUSIONS The use of BB in elderly patients with HFr EF and renal impairment was associated with a better prognosis.Use of BB should be encouraged when possible. | Juan Martínez-Milla Marcelino Cortés García Julia Anna Palfy Mikel Taibo Urquía Marta López Castillo Ana Devesa Arbiol Ana Lucía Rivero Monteagudo María Luisa Martín Mariscal Inés Jiménez-Varas Sem Briongos Figuero Juan Antonio Franco-Pelaéz JoséTuñón | 2021 | Journal of Geriatric Cardiology2021，18，1： | 3 |
| 2 | Te-seeded growth of few-quintuple layer Bi2Te3 nanoplates显示文摘 | Yanyuan Zhao Maria de la Mata Richard L. J. Qiu Jun Zhang Xinglin wen Cesar Magen Xuan P. A. Gao Jordi Arbiol Qihua Xiong | 2014 | Nano Research2014，7，9： | 2 |
| 3 | Insights into the structural and chemical modifications of Nb additive on TiO2 nanopar- titles 显示文摘 | ANA M RUIZ DEZANNEAU G ARBIOL J | 2004 | Chem Mater2004，16，5： | 1 |
| 4 | Effects of Nb doping on the TiO2 natase-to-rutile phase transition显示文摘 | ARBIOL J CERDA J DEZANNEAU G | 2002 | J Appl Phys2002，92，2： | 1 |
| 5 | A Permanent Test Field for Digital Photogrammetric Systems显示文摘 | Honkavaara E Arbiol R Markelin L | | 0，，01： | 1 |
| 6 | Effects of Nb doping on the TiO2 natase-to-rutile phase transition显示文摘 | Arbiol J Cerda J Dezanneau G | 2002 | J Appl Phys2002，92，2： | 1 |
| 7 | Synthesis of nanocrystalline materials for SOFC applications by acrylamide polymerization显示文摘 | Tarancón A Dezanneau G Arbiol J | 2003 | J Power Sources2003，118，12： | 1 |
| 8 | Morphological and structural characterization of WO3 and Cr-WO3 thin films synthesized by so1 gel process 显示文摘 | Mauro Epifani Jordi Arbiol Rafil D i az | 2009 | Thin Solid Films2009，1016，1： | 1 |
| 9 | Synthesis of nanocrystalline materials for SOFC applications by acrylamide polymerization 显示文摘 | Tarancon A Dezanneau G Arbiol J | 2003 | J Power Sources2003，118，12： | 1 |
| 10 | Crystalline structure, defects and gas sensor response to NO2 and H2S of tungsten trioxide nanopowders显示文摘 | Jimenez I Arbiol J Dezanneau G | 2003 | Sensors and Actuators B: Chemical2003，93，13： | 1 |
| 11 | Crystalline structure, defects and gas sensor response to NO2 and H2S of tungsten trioxide nanopowders 显示文摘 | Jimenez I Arbiol J Dezanneau G | 2003 | Sensors and Actuators B2003，93，： | 1 |
| 12 | Crystalline structure, defects and gas sensor response to NO2 and H2S of tungsten trioxide nanopowders显示文摘 | JIME'NEZ I ARBIOL J DEZANNEAU G | 2003 | Sensors and Actuators2003，93，13： | 1 |
| 13 | Analysis of the Noble Metal Catalytic Additives Introduced by Impregnation of as Obtained Sn O2Sol-gel Nanocrystals for Gas Sensors显示文摘 | Cabot A Arbiol J Morante J R | 2000 | Sensors&Actuators B Chemical2000，70，： | 1 |
| 14 | Distributions of noble metal Pd and Pt in mesoporous silica显示文摘 | ARBIOL J CABOT A MORANTE J R | 2002 | Appl Phys Lett2002，81，18： | 1 |
| 15 | Structural and Gas-Sensing Properties of WO3 Nanocrystalline Powders Obtained by a Sol-Gel Method From Tungstic Acid显示文摘 | Jiménez I Arbiol J | 2002 | IEEE SENSORS JOURNAL2002，2，4： | 1 |
| 16 | Perovskite-type BaSnO3 powders for high temperature gas sensor applications 显示文摘 | Cerda J Arbiol J Dezanneau G | 2002 | Sensors and Actualors B2002，84，： | 1 |
| 17 | Analysis of the noble metal catalytic additives introduced by impregnation of as obtained SnO2 so-gel nanocrystals for gas sensor显示文摘 | Cabot A Arbiol J Morante J R | 2000 | Sensor and Actuators B2000，，70： | 1 |
| 18 | Crystalline structure,defects and gas sensor response to NO2 and H2S of tungsten trioxide nanopowders显示文摘 | Jimenez I Arbiol J Dezanneau G | 2003 | Sensors and Actuators B2003，93，： | 1 |
| 19 | Nanostructured metal oxides synthesized by hard template method for gas sensing applications 显示文摘 | ROSSINYOL E ARBIOL J PEIR0 F | 2005 | Sens Actuaors B2005，109，1： | 1 |
| 20 | Bi2O3 as a selective sensing material for NO detection显示文摘 | Cabot A Marsal A Arbiol J | 2004 | Sensors and Actuators B2004，99，： | 1 |
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