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| 1 | Association of Helicobacter pylori IgA antibodies with the risk of peptic ulcer disease and gastric cancer显示文摘AIM: To compare the prevalence of Helicobacter pylori (Hpylori) IgG and IgA antibodies between adult subjects,with defined gastric diseases, nondefined gastric disorders and those representing the population.METHODS: Data on H pylori IgG and IgA antibodies,determined by enzyme immunoassay, were analyzed in 3 252 subjects with DGD including 482 patients with gastric ulcer, 882 patients with duodenal ulcer, 1 525patients with chronic gastritis only and 363 subjects with subsequent gastric cancer, 19 145 patients with NoDg and4 854 POPUL subjects. The age-adjusted prevalences were calculated for 1- and 20-year age cohorts.RESULTS: The prevalences of IgG antibodies were equally high (89-96%) in all 20-year age cohorts of the DGD groups, whereas the prevalences of IgG antibodies were lower and increased by age in the POPUL and NoDg groups. The prevalences of IgA antibodies were also higher in the DGD groups; among them CA (84-89%) and GU groups (78-91%) showed significantly higher prevalences than DU (68-77%) and CG patients (59-74%) (OR 2.49, 95%CI 1.86-3.34 between the GU and DU groups). In the CA, GU, and DU groups, the IgA prevalences showed only minor variation according to age, while they increased by age in the CG, POPUL, and NoDg groups (P≤0.0001). The IgA response, but not the IgG response, was associated with an increased risk of CA (OR 2.41, 95%CI 1.79-3.53) and GU (OR 2.57,95%CI 1.95-3.39) in comparison with CG patients.CONCLUSION: An IgA antibody response during H pylori infection is significantly more common in CA and GU patients as compared with CG patients. | Timo U Kosunen Kari Seppl Seppo Sarna Arpo Aromaa Paul Knekt Jarmo Virtamo Anniina Salomaa-Rsnen Hilpi Rautelin | 2005 | World Journal of Gastroenterology2005，11，43： | 3 |
| 2 | Evaluation of the electrochemical activity of a Ti-RuO2-TiO2 permanent anode 显示文摘 | AROMAA J FORSI~N O | 2006 | Electrochimica Acta2006，51，27： | 1 |
| 3 | Vitarmn E and cancer prevention 显示文摘 | Knekt P Aromaa A Maatela J | 1991 | Am J Clin Nutr1991，53，： | 1 |
| 4 | Comparison of pethidine and tilidine in man显示文摘 | Tammisto T Takki S Aromaa U | | 0，，： | 1 |
| 5 | Tumour markers and screening for gastrointestinal cancer: a follow up study in Finland显示文摘 | Hakama M Stenman UH Knekt P Jarvisalo J Leino A Hakulinen T Maatela J Aromaa A | 1994 | J Med Screen1994，1，1： | 1 |
| 6 | Serious complications associated with spinal and epidural anaesthesia in Finland from 2000 to 2009 显示文摘 | PITKANEN M T AROMAA U COZANITIS D A | 2013 | Acta Anaesthesiol Scand2013，57，5： | 1 |
| 7 | Development of superhydrophobic coating on paperboard surface using the liquid flame spray显示文摘 | Teisala H Tuominen M Aromaa M | 2010 | Surface andCoatingsTechnology2010，205，2： | 1 |
| 8 | Evaluation of the electrochemical activity of a Ti-RuO2-TiO2 permanent anode 显示文摘 | Jari Aromaa Forsen Olof | 2006 | Electrochimica Acta2006，51，27： | 1 |
| 9 | Evaluation of the Electrochemical Activity of a Ti - RuOz- TiO2 Permanent Anode 显示文摘 | Aromaa J Forsen O | 2006 | Electrochimica Acta2006，51，27： | 1 |
| 10 | Evaluation of the electrochemical activity of a Ti- RuO2-TiO2 permanent anode显示文摘 | Aromaa J Forsen O | 2006 | Electrochimica Acta2006，51，27： | 1 |
| 11 | Depression and cardiovascular diseases显示文摘 | Aromaa A Raitasalo R Reunanen A | 1994 | Act Psychiatr Stand suppl1994，377，： | 1 |
| 12 | The IL- 1beta genotype carries asthma susceptibility only in men显示文摘 | Karjalainen J Nieminen MM Aromaa A | 2002 | J Allergy Clin Immunol2002，109，： | 1 |
| 13 | Prevalence of stroke in Finland显示文摘 | Aho K Reunanen A Aromaa A | 1986 | Stroke1986，17，4： | 1 |
| 14 | ARNTL (BMAL1) and NPAS2 gene variants contribute to fertility and seasonality 显示文摘 | Kovanen L Saarikoski S T Aromaa A | 2010 | Plops One2010，5，10： | 1 |
| 15 | Development of su- perhydrophobic coating on paperboard surface using the liquid flame spray显示文摘 | TEISALA H TUOMINEN M AROMAA M | 2010 | Surface and Coatings Technology2010，205，2： | 1 |
| 16 | Leakage of fluid around low-pressure tracheal tube cuffs显示文摘 | Oikkon M Aromaa U | 1997 | Anaes-thesia1997，52，： | 1 |
| 17 | Evalyation of the electrochemical activity of a Ti-RuO2-TiO2 permanent anode显示文摘 | Jari Aromaa Olof Fors6n | 2006 | Electrochim- ica Acta2006，51，： | 1 |
| 18 | Determinants of Sciatica and Low-Back Pain显示文摘 | MARKKU HELI?VAARA MATTI M?KEL? PAUL KNEKT OLLI IMPIVAARA APRO AROMAA | 1991 | Spine1991，，6： | 1 |
| 19 | Evaluation of the electrochemical activity of a Ti-RuO2-TIO2 permanent anode 显示文摘 | Aromaa J Forsen O | 2006 | Electro- chemica Acta2006，51，27： | 1 |
| 20 | Comparison of etomidate in combination with fentanyl or diazepam, with thiopentone as an induction agent for general anaesthesia 显示文摘 | KORTTILA K TAMMISTO T AROMAA U | 1979 | Br J Anaesth1979，51，12： | 1 |
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