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| 1 | Stem cell therapy in the management of shoulder rotator cuff disorders显示文摘Rotator cuff tears are frequent shoulder problems that are usually dealt with surgical repair. Despite improved surgical techniques, the tendon-to-bone healing rate is unsatisfactory due to difficulties in restoring the delicate transitional tissue between bone and tendon. It is essential to understand the molecular mechanisms that determine this failure. The study of the molecular environment during embryogenesis and during normal healing after injury is key in devising strategies to get a successful repair. Mesenchymal stem cells(MSC) can differentiate into different mesodermal tissues and have a strong paracrine, anti-inflammatory, immunoregulatory and angiogenic potential. Stem cell therapy is thus a potentially effective therapy to enhance rotator cuff healing. Promising results have been reported with the use of autologous MSC of different origins in animal studies: they have shown to have better healing properties, increasing the amount of fibrocartilage formation and improving the orientation of fibrocartilage fibers with less immunologic response and reduced lymphocyte infiltration. All these changes lead to an increase in biomechanical strength. However, animal research is still inconclusive and more experimental studies are needed before human application. Future directions include expanded stem cell therapy in combination with growth factors or different scaffolds as well as new stem cell types and gene therapy. | Maria Valencia Mora Miguel A Ruiz Ibán Jorge Díaz Heredia Raul Barco Laakso Ricardo Cuéllar Mariano García Arranz | 2015 | World Journal of Stem Cells2015，7，4： | 6 |
| 2 | Governance structures in R&D networks: An analysis in the European context 显示文摘 | ARRANZ N ARROYABE J C F D | 2007 | Technological Forecasting and Social Change2007，74，5： | 1 |
| 3 | Changes in phenolic content of tomato products during storage显示文摘 | Vallverdú-Queralt A Arranz S Medina-Remón A | 2011 | J Agric Food Chem2011，59，17： | 1 |
| 4 | Effect of formal contracts, rela- tional norms and trust on performance of joint re- search and development projects显示文摘 | Arranz N Arroyabe J | 2012 | British Journal of Management2012，23，4： | 1 |
| 5 | Protective effects of orga nosulfur compounds towards N-nitrosamine-induced DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay 显示文摘 | Arranz N Haza A I Garcia A | 2007 | Food and Chemical Toxicology2007，45，9： | 1 |
| 6 | Total homocysteine levels relation with chronic complications of diabetes,body composition, and other cardiovascular risk factors in a population of patients with diabetes mellitus type 2显示文摘 | de Luis DA Fernandez N Arranz ML | 2005 | J Diabet Complicat2005，19，： | 1 |
| 7 | A QTL affecting milk yield and composition maps to bovine chromosome 20: A confirmation 显示文摘 | Arranz J J Coppieters W Berzi P Cambisano N Grisart B Karim L Marcq F Moreau L Mezer C Riquet J Simon P Vanmanshoven P Wagenaar D and Georges M | 1998 | Animal Genetics1998，29，： | 1 |
| 8 | Effect of cis-resveratuol ongenes involved ni nuclear factor kappa B signaling 显示文摘 | Leiro J Arranz JA Fraiz N | 2005 | Int Innunophar- macol2005，5，2： | 1 |
| 9 | Effect of cis-resveratrol on genes involved in nuclear factor kappa B signaling显示文摘 | Leiro J Arranz JA Fraiz N | 2005 | Int Immunopharmacol2005，5，2： | 1 |
| 10 | Total homocysteine levels relation with chronic complications of diabetes,body composition,and other cardiovascular risk factors in a population of patients with diabetes mellitus type 2显示文摘 | de Luis D A Fernandez N Arranz M L | | 0，，01： | 1 |
| 11 | Effect of acu- puncture treatment on the immune function impair- ment found in anxious women显示文摘 | Arranz L Guayerbas N Siboni L | 2007 | Am J Chin Med2007，35，1： | 1 |
| 12 | A comparative clinical study of short-term results of laparoscopic surgery for rectal cancer during the learning curve显示文摘 | Ivan Arteaga González Hermógenes Díaz Luis Antonio Martín Malagón Eudaldo M. López-Tomassetti Fernández Javier Arranz Duran ángel Carrillo Pallares | 2006 | International Journal of Colorectal Disease2006，，6： | 1 |
| 13 | Total homocysteine levels relation with chronic complications of diabetes,body composition,and other cardiovascular risk factors in a population of patients with diabetes mellitus type 2显示文摘 | De Luis DA Fernandez N Arranz ML | 2005 | J Diabetes Complications2005，19，1： | 1 |
| 14 | Total homocysteine levels relation with chronic complications of diabetes, body composition, and other cardiovascular risk factors in a population of patients with diabetes mellitus type 2 显示文摘 | de Luis DA Fernandez N Arranz ML | 2005 | J Diabetes Complications2005，19，1： | 1 |
| 15 | Effect of cis-resveratrol on genes involved in nuclear factor kappa B signaling显示文摘 | Leiro J Arranz JA Fraiz N | 2005 | Int Immunopharmacol2005，5，2： | 1 |
| 16 | Genetic variation at microsatellite loci in Spanish Sheep显示文摘 | Arranz J J Bayón Y Primitivo F S | 2001 | Small Ruminant Research2001，39，1： | 1 |
| 17 | Genetic Relationships among Spanish Sheep Using Microsatellites显示文摘 | Arranz J J Bayón Y Primitivo F S | 1998 | Animal Genetics1998，29，： | 1 |
| 18 | VIP reverses the expression profiling of TLR4-stimulated signaling pathway in rheumatoid arthritis synovial fibroblasts显示文摘 | Arranz A Gutiérrez-Canas I Carrión M | 2008 | Mol Immunol2008，45，11： | 1 |
| 19 | Protective effects of organosulfur compounds towards N - nitrosamine - induced DNA damage in the single - cell gel electrophoresis (SCGE)/HepG2 assay 显示文摘 | Arranz N Haza A I Garcia A | 2007 | Food and Chemical Toxicology2007，45，9： | 1 |
| 20 | The choice of partners in R&I) cooperation: an empirical analysis of Spanish firms显示文摘 | Arranz N de Arroyabe J C F | 2008 | Technovation2008，28，88： | 1 |
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