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| 1 | Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultra structural changes of pancreatic beta - cells in experimental diabetes in rats 显示文摘 | Arulselvan P Subramanian S P | 2007 | Chem Biol Interact2007，165，2： | 1 |
| 2 | Effect of mangiferin isolated from Salacia chinensis regulates the kidney carbohydrate metabolism in streptozotocin-induced diabetic rats 显示文摘 | Sellamuthu P S Arulselvan P Muniappan B P | 2012 | Asian Pac J Trop Biomed2012，2，3： | 1 |
| 3 | Anticancer potential of Alternanthera sessilis extract on HT-29 human colon cancer cells显示文摘Objective: To identify the bioactive extracts from Alternanthera sessilis and investigate its cytotoxicity potential against colon cancer cells, HT-29. Methods: This study examined the effects of three parts(aerial, leaf, stem) of whole plant on HT-29 colon cancer cell lines. Three different extracts from the plant parts were prepared by maceration technique using 80% ethanol. The anticancer activities were determined using MTT, clonogenic, cell motility and AOPI assay. The chemical composition profiling was analyzed by GC-MS. Results: Among three plant part extracts, leaf extract greatly suppressed the growth of colon cancer cells in time and dosage-dependent manner, followed by aerial and stem. The cytotoxicity results were rationalized with clonogenic, cell motility and AO/PI assay, where extract showed the most active activity compared to aerial and stem extracts. GC-MS analysis of leaf extract showed there were various recognized anti-cancer, anti-oxidant and anti-inflammatory compounds. Conclusions: Amid the screened extracts, the leaf extract exhibits the credible cytotoxic, anti-proliferative and apoptotic activity and hence, our findings call for additional research to conclude the active compounds and their mechanisms determining the apoptotic activity. | Sivapragasam Gothai Katyakyini Muniandy Norhaizan Mohd Esa Suresh Kumar Subbiah Palanisamy Arulselvan | 2018 | Asian Pacific Journal of Tropical Biomedicine2018，8，8： | 1 |
| 4 | Anti-diabtic activity of fruits of Terminalia chebula on streptozotocin induced diabetic rats 显示文摘 | Kumar GPS Arulselvan P Kumar DS | 2006 | J Health sci2006，52，3： | 1 |
| 5 | Drug delivery system for an anticancer agent, chlorogenate-Zn/Al-layered double hydroxide nanohybrid synthesised using direct co-precipitation and ion exchange methods显示文摘 | Farahnaz Barahuie Mohd Zobir Hussein Palanisamy Arulselvan Sharida Fakurazi Zulkarnain Zainal | 2014 | Journal of Solid State Chemistry2014，，： | 1 |
| 6 | RC infilled frame-RC plane frame interaction for seismic resistance显示文摘 | Suyamburaja Arulselvan Subramanian K Perumal Pillai E B Santhakumar A R | 2007 | Journal of Applied Sciences2007，7，7： | 1 |
| 7 | Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultra structural changes of pancreatic β-cells in experimental diabetes in rats 显示文摘 | ARULSELVAN P SUBRAMANIAN S P | 2007 | Chem-Biol Interact2007，165，2： | 1 |
| 8 | Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultra structural changes of pancreatic β-cells in experimental diabetes in rats显示文摘 | Palanisamy Arulselvan Sorimuthu Pillai Subramanian | 2006 | Chemico-Biological Interactions2006，，2： | 1 |
| 9 | Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimen?tal rats through their antioxidant nature 显示文摘 | Fakurazi S Sharifudin SA Arulselvan P | 2012 | Molecules2012，17，7： | 1 |
| 10 | Attenuation of lipopolysaccharide-induced neuroinflammatory events in BV-2 microglial cells by Moringa oleifera leaf extract显示文摘Objective: To determine the anti-neuroinflammatory activity of Moringa oleifera leaf extract(MLE) under lipopolysaccharide stimulation of mouse murine microglia BV2 cells in vitro. Methods: The cytotoxicity effect of MLE was investigated by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide assay. The inflammatory response of BV-2 cells were induced with lipopolysaccharide. The generation of nitric oxide levels was determined by using Griess assay and the level of pro-inflammatory cytokines(IL-1β, IL-6 and TNF-α) was evaluated by ELISA kit. The expression of iNOS, COX-2 as well as IκB-ααwas carried out by immunoblot analysis. Results: MLE reduced the nitric oxide production in concentration-dependent manner, and maintained the viability of BV-2 microglial cells which indicated absence of toxicity. In addition, MLE repressed the activation of nuclear factor kappa B by arresting the deterioration of IκB-α, consequently resulted in suppression of cytokines expression such as COX-2 and iNOS. Conclusions: MLE inhibitory activities are associated with the inhibition of nuclear factor kappa B transcriptional activity in BV2 microglial cells. Thus MLE may offer a substantial treatment for neuroinflammatory diseases. | Gothai Sivaprakasam Palanivel Ganesan Katyakyini Muniandy Shin-Young Park Duk-Yeon Cho Joon-So Kim Palanisamy Arulselvan Dong-Kug Choi | 2019 | Asian Pacific Journal of Tropical Biomedicine2019，9，3： | 0 |
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