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9篇 您的检索式:作者名="Ashok Kumar L"
    题名 作者 年代 出处 被引量
1Methanolic extract of Momordica cymbalaria enhances glucose uptake in L6 myotubes in vitro by up-regulating PPAR-γ and GLUT-4显示文摘The present study was undertaken to evaluate the influence of the methanolic fruit extract of Momordica cymbalaria(MFMC) on PPARγ(Peroxisome Proliferator Activated Receptor gamma) and GLUT-4(Glucose transporter-4) with respect to glucose transport. Various concentrations of MFMC ranging from 62.5 to 500 μg·mL-1 were evaluated for glucose uptake activity in vitro using L6 myotubes, rosiglitazone was used as a reference standard. The MFMC showed significant and dose-dependent increase in glucose uptake at the tested concentrations, further, the glucose uptake activity of MFMC(500 μg·mL-1) was comparable with rosigilitazone. Furthermore, MFMC has shown up-regulation of GLUT-4 and PPARγ gene expressions in L6 myotubes. In addition, the MFMC when incubated along with cycloheximide(CHX), which is a protein synthesis inhibitor, has shown complete blockade of glucose uptake. This indicates that new protein synthesis is required for increased GLUT-4 translocation. In conclusion, these findings suggest that MFMC is enhancing the glucose uptake significantly and dose dependently through the enhanced expression of PPARγ and GLUT-4 in vitro.Puttanarasaiah Mahesh Kumar Marikunte V Venkataranganna Kirangadur Manjunath Gollapalle L Viswanatha Godavarthi Ashok 2014Chinese Journal of Natural Medicines2014,12,12:2
2Exploiting rice-sorghum synteny for targeted devel- opment of EST-SSRs to enrich the sorghum gene- tic linkage map 显示文摘Ramu P Kassahun B Senthilvel S Ashok Kumar C Jayashree B Folkertsma RT Ananda Reddy L Kuruvinashetti MS Haussmann BIG Hash CT 2009Theor Appl Genet2009,119,7:1
3In vitro alpha-amylase inhibition and in vivo antioxidant potential ofAmaranthus spinosus in alloxan-induced oxidative stress in diabetic rats 显示文摘Kumar B S Ashok L K Nandeesh R 2009JPlant Biol2009,36,3:1
4A Model for Activity Coef- ficient of Pz 05 in BOF Slag and Phosphorus Distribution Between Liquid Steel and Slag 显示文摘Somnath B Ashok Kumar L Seshadri S 2007ISIJ International2007,47,8:1
5Activity of Iron Ox- ide in Steelmaking Slag 显示文摘Somnath B Ashok Kumar L Seshadri S 2008Metallurgical and Materials Trans- actions2008,39,6:1
6Serf-healing coatings for steel 显示文摘Kumar Ashok Stephenson L D 2006Progress in Organic Coatings2006,55,:1
7The role of template in the enzymatic synthesis of conducting polyaniline显示文摘Wei Liu Ashok L Cholli Ramaswamy Nagarajan Jayant Kumar Sukant Tripathy Ferdinando F Bruno Lynne Samuelson 1999J Am Chem Soc1999,121,11:1
8Deposition and characterization of titanium carbide coatings using laser ablation method 显示文摘Ashok Kumar Chan H L Kapat J S 1998Applied Surface Science1998,,:1
9Activity of iron oxide in steelmaking slag显示文摘Somnath B Ashok Kumar L Seshadri S 2008Metallurgical and Materials Transactions B2008,39,6:1
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