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| 1 | Photodynamic therapy vs radiofrequency ablation for Barrett's dysplasia: Efficacy,safety and cost-comparison显示文摘AIM:To compare effectiveness,safety,and cost of photodynamic therapy(PDT)and radiofrequency ablation(RFA)in treatment of Barrett’s dysplasia(BD).METHODS:Consecutive case series of patients undergoing either PDT or RFA treatment at single center by a single investigator were compared.Thirty-three patients with high-grade dysplasia(HGD)had treatment with porfimer sodium photosensitzer and 630 nm laser(130 J/cm),with maximum of 3 treatment sessions.Fifty-three patients with BD(47 with low-grade dysplasia-LGD,6 with HGD)had step-wise circumferential and focal ablation using the HALO system with maximum of 4 treatment sessions.Both groups received proton pump inhibitors twice daily.Endoscopic biopsies were acquired at 2 and 12 mo after enrollment,with 4-quadrant biopsies every 1 cm of the original BE extent.A complete histological resolution response of BD(CR-D)was defined as all biopsies at the last endoscopy session negative for BD.Fisher’s exact test was used to assess differences between the two study groups for primary outcomes.For all outcomes,a two-sided P value of less than 0.05 was considered to indicate statistical significance.RESULTS:Thirty(91%)PDT patients and 39(74%)RFA were men(P=0.05).The mean age was 70.7±12.2 and 65.4±12.7(P=0.10)year and mean length of BE was 5.4±3.2 cm and 5.7±3.2 cm(P=0.53)for PDT and RFA patients,respectively.The CR-D was(18/33)54.5%with PDT vs(47/53)88.7%with RFA(P=0.001).One patient with PDT had an esophageal perforation and was managed with non-surgical measures and no perforation was seen with RFA.PDT was five times more costly than RFA at our institution.The two groups were not randomized and had different BD grading are the limitations of the study.CONCLUSION:In our experience,RFA had higher rate of CR-D without any serious adverse events and was less costly than PDT for endoscopic treatment of BD. | Atilla Ertan Irum Zaheer Arlene M Correa Nirav Thosani Shanda H Blackmon | 2013 | World Journal of Gastroenterology2013，19，41： | 7 |
| 2 | Surgical treatment of eyelidtunlors显示文摘 | Kurt RA Yalcindag N Atilla H | | 0，，3： | 1 |
| 3 | Recent advances in nanoparticles and nanospheres显示文摘 | Hincal A Atilla Kas H | 1997 | Miomed Sci Technol1997，12，1： | 1 |
| 4 | Pattern electroretinog- raphy and visual evoked potentials in optic nerve diseases 显示文摘 | Atilla H Tekeli O Ornek K | 2006 | J Clin Neurosci2006，13，1： | 1 |
| 5 | Effects of intracameral lidocaine on ocular tissues显示文摘 | Atilla H Tekeli O Can B | 2003 | Clin Experiment Ophthalmol2003，31，1： | 1 |
| 6 | Gingival crevicular fluid monocyte chemoattractant protein-1 and RANTES levels in patients with generalized aggressive periodontitis显示文摘 | Emingil G Atilla G Hüseyinov A | 2004 | J Clin Periodontol2004，31，10： | 1 |
| 7 | Position of the acetabular component determines the fate of femoral head autografts in totalhip replacement for acetabular dysplasia 显示文摘 | Atilla B Ali H Aksoy M C | 2007 | J Bone Joint Surg Br2007，89，7： | 1 |
| 8 | TLR2 Arg753Gly, TLR4 Asp299Gly and Thr399Ile gene polymorphisms are not associated with chronic periodontitis in a Turkish population显示文摘 | Berdeli A Emingil G Han Saygan B Gtirkan A Atilla G Kose T Baylas H | 2007 | J Clin Periodontol2007，34，7： | 1 |
| 9 | Position of the ace- tabular component determines the fate of femoral head au- tografts in total hop replacement for acetabular dysplasia 显示文摘 | Atilla B Ali H Aksoy M C | 2007 | J Bone Joint Surg(Br)2007，89，7： | 1 |
| 10 | The hirsutism scoring system should be population specific显示文摘 | Hikmet Hass H Mete Tanir Atilla Yidirim | 2005 | Fertil Steri12005，84，3： | 1 |
| 11 | Uhrastruetural analysis of metallic debris and tissue reaction around spinal implants in patients with late operative site pain 显示文摘 | Senaran H Atilla P Kaymaz F | 2004 | Spine2004，29，15： | 1 |
| 12 | Undescended testes in adults : clinical significance of resistive index values of the testicular artery measured by Doppler ultrasound as a predictor of testicular histology 显示文摘 | Atilla MK Sargin H Ylmaz Y | 1997 | J Urol1997，158，31： | 1 |
| 13 | The oph- thalmology surgical competency assessment rubric for strabismus surgery显示文摘 | Golnik KC Motley WW Atilla H | 2012 | J AAPOS2012，16，4： | 1 |
| 14 | Intraocular Pressure Values Obtained by Ocular Response Analyzer, Dynamic Contour Tonometry, and Goldmann Tonometry in Keratokonic Corneas显示文摘 | Atilla Bayer Afsun Sahin Volkan Hürmeri? G?khan ?zge | 2010 | Journal of Glaucoma2010，，8： | 1 |
| 15 | Inflammatory pigmented paravenous retinochoroidal atrophy显示文摘 | Batioglu F Atmaca LS Atilla H | 2002 | Eye (Lond)2002，16，1： | 1 |
| 16 | Assoeiations of plasma natriuretic peptide, adrenomedullin,and homocysteine levels with alterations in arterial stiffuess:the framingham heart study显示文摘 | Daniel L Shih - Jen H Atilla K | 2007 | Circulation2007，115，： | 1 |
| 17 | Uhrastructural analysis of metallic debris and tissue reaction around spinal implants in patients with late operative site pain显示文摘 | Senaran H Atilla P Kaymaz F | 2004 | Spine2004，29，15： | 1 |
| 18 | Effects of intracameral lidocain on ocular tissues显示文摘 | Atilla H Tekeli O Can B el al | 2003 | Clin Experimem Ophthalmo12003，31，1： | 1 |
| 19 | Recent advances in nanoparticles and nanospheres显示文摘 | Atilla H A Suheyla K H | 1997 | Biomed Sci Technol1997，3139，： | 1 |
| 20 | Changes of micronutrients, dry weight and chlorophyll contents in strawberry plants under salt stress condi- tions 显示文摘 | Esechie H Ece T Atilla E | 2005 | Commun Soil Sci Plan2005，36，： | 1 |
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