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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | FunctiOnal MRI-BOLD of brainstem structures during visually triggered migraine 显示文摘 | Cao Y Aurora SK Naqesh V | 2002 | Neurology2002，59，1： | 1 |
| 3 | HYPERAGGREGATING EFFECT OF HYDROXYETHYL STARCH COMPONENTS AND UNIVERSITY OF WISCONSIN SOLUTION ON HUMAN RED BLOOD CELLS: A RISK OF IMPAIRED GRAFT PERFUSION IN ORGAN PROCUREMENT?显示文摘 | Aurora M. Morariu Arjan vd Plaats Wim v Oeveren Nils A. ?t Hart Henri G.D. Leuvenink Reindert Graaff Rutger J. Ploeg Gerhard Rakhorst | 2003 | Transplantation2003，，1： | 1 |
| 4 | Functional MRI - BOLD of brainstem structures during visually triggered migraine显示文摘 | Cao Y Aurora SK Nagesh V | 2002 | Neurology2002，59，1： | 1 |
| 5 | Glycation of lysinecontaining dipeptide 显示文摘 | Cannela M Marianna V Aurora N | 2006 | J Peptide Sci2006，12，4： | 1 |
| 6 | Functional MRI-BOLD of brainstem structures during visually triggered migraine 显示文摘 | Cao Y Aurora SK Nagesh V | 2002 | Neurology2002，59，： | 1 |
| 7 | Molecular Epidemiology of Escherichia coli Producing Extended - spectrum β- Laetamases Isolated in Rome ,Italy显示文摘 | Alessandra C Aurora G F Paola V | 2008 | J Clin Mierob2008，46，1： | 1 |
| 8 | High-temperature laser interferometer for thermal expansion and optical length measurements 显示文摘 | Aurora T S Day S M King V | 1984 | Rev Sci Instrum1984，55，2： | 1 |
| 9 | Alleleohemical stress cau- ses inhibition of growth and oxidative damage in Lyeopersicon escuien- turn Mizz显示文摘 | Aurora L N Teresa R R Joseluis V | 2006 | Plant Cell and Environment2006，，29： | 1 |
| 10 | Periaque- ductal gray matter dysfunction in migraine: cause or the burden of illness? 显示文摘 | Welch K M Nagesh V AuroraS K | 2001 | Headache2001，41，： | 1 |
| 11 | High-pressure processing technologies for the pasteurization and sterilization of foods显示文摘 | Hugo M P Aurora V F Carole T S | 2011 | Food Bioprocess Techenology2011，4，6： | 1 |
| 12 | Periaqueductal gray matter dysfunction in mrgraine:cause or the burden of illness显示文摘 | Welch KM Nagesh V Aurora SK | | 0，，07： | 1 |
| 13 | 1, 10- Phenanthroline-cuprous ion complex, a potent inhibitor of DNA and RNA polymerases显示文摘 | D'Aurora V Stern A M Sigman D S | 1978 | Biochem Biophys Res Communications1978，80，41： | 1 |
| 14 | Oxygen- dependent cleavage of DNA by the 1,10-phenanthroline- cuprous complex 显示文摘 | Sigman D S Graham D R Aurora V D | 1979 | J Bio Chem1979，254，12： | 1 |
| 15 | A symbolic fault-prediction model based on multiobjective particle swarm optimization 显示文摘 | Andre B C Aurora P Silvia R V | 2010 | The Journal of Systems and Software2010，83，5： | 1 |
| 16 | Oxygen - dependent cleavage of DNA by the 1, 10 - phenanthroline - cuprous complex显示文摘 | SIGMAN D S GRAHAM D R AURORA V D | 1979 | J Biol Chem1979，254，12： | 1 |
| 17 | Periaqueductal gray matter dysfunction in migraine:cause or the burden of illness显示文摘 | Welch K M Nagesh V Aurora S K | 2001 | Headache2001，41，7： | 1 |
| 18 | High-pressure pro- cessing technologies for the pasteurization and sterilization of foods显示文摘 | Hugo M P Aurora V F Carole T S | 2011 | Food Bioprocess Technology2011，4，96： | 1 |
| 19 | Molecular epidemiology of Escherichia coli producing extended-spectrum β -Lactamases isolated in Rome,Italy显示文摘 | Alessandra C Aurora G F Paola V | 2008 | J Clin Microb2008，46，1： | 1 |
| 20 | Functional MRI-BOLD of brainstem structures during visually triggered migraine显示文摘 | Cao Y Aurora SK Naqesh V | | 0，，01： | 1 |
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